Results 131 to 140 of about 40,840 (280)

Increased adhesive properties of neutrophils in sickle cell disease may be reversed by pharmacological nitric oxide donation

open access: yesHaematologica, 2008
Increased leukocyte adhesion to vascular endothelium contributes to vaso-occlusion in sickle cell disease. Since nitric oxide bioavailability is decreased in sickle cell disease and nitric oxide may inhibit leukocyte adhesion, we investigated whether ...
Andreia A. Canalli   +4 more
doaj   +1 more source

Modulation of swimming in the gastropod Melibe leonina by nitric oxide [PDF]

open access: yes, 2002
Nitric oxide (NO) is a gaseous intercellular messenger produced by the enzyme nitric oxide synthase. It has been implicated as a neuromodulator in several groups of animals, including gastropods, crustaceans and mammals.
Newcomb, James M.   +1 more
core   +1 more source

Comparison of sGC activator and sGC stimulator in 5/6 nephrectomized rats on high-salt-diet

open access: yesFrontiers in Pharmacology
IntroductionSoluble guanylate cyclase (sGC) stimulators and activators are known to enhance kidney function in various models of chronic kidney disease (CKD) by increasing cyclic guanosine monophosphate (cGMP).
Xin Chen   +17 more
doaj   +1 more source

Activation of guanylate cyclase by sodium azide in rat adipocytes [PDF]

open access: bronze, 1976
Jacqueline Levilliers   +3 more
openalex   +1 more source

Management of Pulmonary Arterial Hypertension: Current Strategies and Future Prospects

open access: yesLife
Primary pulmonary hypertension (PPH), now known as pulmonary arterial hypertension (PAH), has induced significant treatment breakthroughs in the past decade.
Munish Sharma   +5 more
doaj   +1 more source

YC-1, a Nitric Oxide-Independent Activator of Soluble Guanylate Cyclase, Inhibits the Spontaneous Contractions of Isolated Pregnant Rat Myometrium

open access: yesJournal of Pharmacological Sciences, 2004
The aim of this study was to investigate the effect of YC-1 (3-(5′-hydroxymethyl-2′-furyl)-1-benzyl indazole) on spontaneous contractions and levels of cyclic GMP (cGMP) of myometrial strips isolated from pregnant rats.
Ali Cetin   +5 more
doaj  

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