Results 71 to 80 of about 804,908 (352)

Eotaxin: a potent eosinophil chemoattractant cytokine detected in a guinea pig model of allergic airways inflammation. [PDF]

, 1994
Eosinophil accumulation is a prominent feature of allergic inflammatory reactions, such as those occurring in the lung of the allergic asthmatic, but the endogenous chemoattractants involved have not been identified.
Collins, PD, Griffiths-Johnson, DA, Hsuan, JJ, Jose, PJ, Moqbel, R, Totty, NF, Truong, O, Walsh, DT, Williams, TJ   +8 more
core   +1 more source

Macrophage Targeting Protects Nerve Structure and Improves Muscle Innervation in a Mouse Model of Charcot‐Marie‐Tooth 2J

Glia, EarlyView.
Hemizygous P0T124M mice develop a late‐onset axonopathy at 18 months of age. Pharmacological macrophage targeting with PLX5622 prevents distal axon degeneration in P0T124M mutant mice and mitigates motor impairment. ABSTRACT In several previous studies, we have shown that macrophage targeting with the CSF‐1 receptor specific kinase (c‐FMS) inhibitor ...
Dennis Klein, Neslim Ercan, Xidi Yuan, Ghjuvan' Ghjacumu Shackleford, Anke Claessens, M. Laura Feltri, Lawrence Wrabetz, Maurizio D'Antonio, Rudolf Martini   +8 more
wiley   +1 more source

Postexposure Protection of Guinea Pigs against a Lethal Ebola Virus Challenge Is Conferred by RNA Interference

Journal of Infectious Diseases, 2006
BackgroundEbola virus (EBOV) infection causes a frequently fatal hemorrhagic fever (HF) that is refractory to treatment with currently available antiviral therapeutics.
T. Geisbert, L. Hensley, E. Kagan, E. Z. Yu, J. Geisbert, Kathleen M. Daddario-DiCaprio, Elizabeth A. Fritz, P. Jahrling, K. Mcclintock, Janet R. Phelps, Amy C. H. Lee, A. Judge, L. Jeffs, I. Maclachlan   +13 more
semanticscholar   +1 more source

Effects of Financial Development on Investments: New Evidence Considering Different Aspects of Financial Development

International Journal of Finance &Economics, EarlyView.
ABSTRACT This paper provides new evidence and insights about the finance‐investment nexus by assessing and comparing the impacts of different aspects of financial development on investment. The study uses data for 88 countries from 1996 to 2019, and the estimates are based on dynamic panel data methodology.
Gabriel Caldas Montes, Vinícius Oliveira   +1 more
wiley   +1 more source

Characterization of a Second Bovine Rotavirus Serotype [PDF]

, 1987
Bovine rotavirus (BRV) V 1005 was characterized by two-way cross-neutralization tests as a second serotype of BRV. Virions and inner shell particles of 65 nm and 55 nm diameter respectively, and empty capsids of 65 nm and 55 nm diameter were separated by
Büssow, Harald, Eichhorn, Werner, Fryder, V., Marc-Martin, S., Sidoti, J.   +4 more
core   +1 more source

Dextromethorphan versus Dextrorphan: A Quantitative Comparison of Antitussive Potency following Separate Administration of Metabolite

The Journal of Clinical Pharmacology, EarlyView.
Abstract To assess the antitussive effects of dextrorphan (DOR) relative to its parent compound, dextromethorphan (DEX) a double‐blind, randomized, placebo‐controlled crossover study was conducted in 23 healthy volunteers using citric acid cough challenge test after administering placebo, DEX, or DOR.
Saeed Rezaee, Caroline E. Wright, Alyn H. Morice, Amin Rostami‐Hodjegan   +3 more
wiley   +1 more source

College Kids with Guns: Hidden in Plain Sight [PDF]

, 2012
Sunday morning found me out in the field with a stalwart group of Gettysburg devotees: the Gettysburg Discussion Group\u27s annual spring Muster. When the coordinator of this year\u27s Muster put out the call for something a bit different, perhaps ...
Rudy, John M.
core   +1 more source

Multiomics Reveal Associations Between CpG Methylation, Histone Modifications and Transcription in a Species That has Lost DNMT3, the Colorado Potato Beetle

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Despite lacking DNMT3, EM‐seq revealed CpG methylation in the Colorado potato beetle. CUT&Tag analysis showed an association of H3K36me3 and H3K27ac with transcription, with H3K36me3 mirroring CpG methylation, demonstrating epigenetic flexibility.
Zoe M. Länger, Elisa Israel, Jan Engelhardt, Agata I. Kalita, Claudia I. Keller Valsecchi, Joachim Kurtz, Sonja J. Prohaska   +6 more
wiley   +1 more source

A Nation of Guinea Pigs. By Marshall S. Shapo [PDF]

, 1981
Empati mellan interaktionsdesigners och utvecklare är viktigt för att samarbetet ska fungera och för att parterna ska kunna kommunicera med varandra. Detta tillsammans med förmågan att se situationer ur varandras perspektiv är något som påverkar ...
Furrow, Barry R.
core   +1 more source

Otopathologic Patterns of Cellular Degeneration in the Peripheral Vestibular Organ Secondary to Head Trauma

The Laryngoscope, EarlyView.
This study examines vestibular degeneration following head trauma, comparing cases with and without fractures. Histopathological analysis of 26 temporal bones showed more severe damage in nonfracture cases, particularly in Scarpa's ganglion cells and vestibular hair cells.
Tomotaka Shimura, Mio Takeuchi, Nevra Keskin Yilmaz, Dilshan Rajan, Sebahattin Cureoglu, Sei Kobayashi, Rafael da Costa Monsanto   +6 more
wiley   +1 more source