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Current Opinion in Clinical Nutrition and Metabolic Care, 2008 To summarize recent studies on the regulation and the functions of the gut-brain axis.Visual cues of food and food intake interact with the gut-brain axis at the level of the hypothalamus. However, the hypothalamic response to glucose intake is considerably altered in patients with type 2 diabetes mellitus, indicating involvement of the hypothalamus in
Romijn, Johannes A. +3 more
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Annual Review of Medicine, 2022
Preclinical evidence has firmly established bidirectional interactions among the brain, the gut, and the gut microbiome. Candidate signaling molecules and at least three communication channels have been identified. Communication within this system is nonlinear, is bidirectional with multiple feedback loops, and likely involves interactions between ...
Emeran A, Mayer +2 more
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Preclinical evidence has firmly established bidirectional interactions among the brain, the gut, and the gut microbiome. Candidate signaling molecules and at least three communication channels have been identified. Communication within this system is nonlinear, is bidirectional with multiple feedback loops, and likely involves interactions between ...
Emeran A, Mayer +2 more
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Acta Endocrinologica (Bucharest), 2023
Epidemic of obesity is ongoing and did not slow down. Causes of obesity are numerous and very complex. Among them, the concept of bidirectional signaling within the brain-gut-microbiome axis was recently proposed as possible pathophysiological mechanism and become a hot topic in the explanations for the control of food intake.
Dr, Micic +3 more
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Epidemic of obesity is ongoing and did not slow down. Causes of obesity are numerous and very complex. Among them, the concept of bidirectional signaling within the brain-gut-microbiome axis was recently proposed as possible pathophysiological mechanism and become a hot topic in the explanations for the control of food intake.
Dr, Micic +3 more
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Science Signaling, 2023
Stress-induced changes in gut microbiota cause γδ T cell migration to the meninges, where they affect behavior in mice.
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Stress-induced changes in gut microbiota cause γδ T cell migration to the meninges, where they affect behavior in mice.
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Best Practice & Research Clinical Gastroenterology, 2014
Currently the only effective treatment for morbid obesity with a proven mortality benefit is surgical intervention. The underlying mechanisms of these surgical techniques are unclear, but alterations in circulating gut hormone levels have been demonstrated to be at least one contributing factor.
Buhmann, Helena +2 more
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Currently the only effective treatment for morbid obesity with a proven mortality benefit is surgical intervention. The underlying mechanisms of these surgical techniques are unclear, but alterations in circulating gut hormone levels have been demonstrated to be at least one contributing factor.
Buhmann, Helena +2 more
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Microbes and the gut‐brain axis
Neurogastroenterology & Motility, 2012AbstractBackground The ‘gut‐brain’ or ‘brain‐gut axis’, depending on whether we emphasize bottom‐up or top‐bottom pathways, is a bi‐directional communication system, comprised of neural pathways, such as the enteric nervous system (ENS), vagus, sympathetic and spinal nerves, and humoral pathways, which include cytokines, hormones, and neuropeptides ...
P, Bercik, S M, Collins, E F, Verdu
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SnapShot: The microbiota-gut-brain axis
Cell, 2021Animals have co-evolved with a vast diversity of microorganisms, collectively named the microbiome, which are important modulators of host gastrointestinal, immune, metabolic, and behavioral functions. In this SnapShot, we provide an overview of the neurodevelopmental and functional influence of host-microbial interactions in the "microbiota-gut-brain ...
Gulistan, Agirman, Elaine Y, Hsiao
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Debugging the gut-brain axis in depression
Cell Host & Microbe, 2022In this issue of Cell Host & Microbe, Li et al. take a step toward a better understanding of the microbiome-gut-brain axis in mental health. They report gastrointestinal testosterone degradation by a specific bacterial strain as a potential mechanism impacting symptom expression in males with depression.
Cassandra E, Gheorghe +2 more
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Schizophrenia and the gut–brain axis
Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2015Several risk factors for the development of schizophrenia can be linked through a common pathway in the intestinal tract. It is now increasingly recognized that bidirectional communication exists between the brain and the gut that uses neural, hormonal, and immunological routes.
Katlyn, Nemani +3 more
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