Results 71 to 80 of about 2,218,817 (239)

A mechanism by which gut microbiota elevates permeability and inflammation in obese/diabetic mice and human gut

Gut, 2023
Objective Ample evidence exists for the role of abnormal gut microbiota composition and increased gut permeability (‘leaky gut’) in chronic inflammation that commonly co-occurs in the gut in both obesity and diabetes, yet the detailed mechanisms involved
S. Mishra, Bo Wang, Shalini Jain, Jingzhong Ding, Jared J. Rejeski, C. Furdui, D. Kitzman, S. Taraphder, C. Bréchot, Ambuj Kumar, H. Yadav   +10 more
semanticscholar   +1 more source

An application of deep learning model InceptionTime to predict nausea, vomiting, diarrhoea, and constipation using the gastro-intestinal pacemaker activity drug database (GIPADD)

Scientific Reports
The accurate preclinical prediction of adverse drug reactions (ADRs), such as nausea and vomiting, remains a challenge. The Gastro-Intestinal Pacemaker Activity Drug Database (GIPADD) ( http://www.gutrhythm.com/public_database ) is a new source of ...
Hephaes Chuen Chau, Julia Yuen Hang Liu, John Anthony Rudd   +2 more
doaj   +1 more source

Genomic variability of lipooligosaccharide biosynthesis locus and sequence type among Campylobacter jejuni isolated from patients with Guillain-Barré syndrome

Microbiology Spectrum
Lipooligosaccharide (LOS) is a crucial component of the Campylobacter jejuni (C. jejuni) cell membrane that mimics human gangliosides and can induce autoimmune neuropathies like Guillain-Barré syndrome (GBS). Approximately one in 1,000 C.
Md. Abu Jaher Nayeem, Shoma Hayat, Asaduzzaman Asad, Md. Golam Mostafa, Shah Nayeem Faruque, Ruma Begum, Mosabbir Ahmed, Yearul Kabir, Israt Jahan, Zhahirul Islam   +9 more
doaj   +1 more source

Trastornos de la interacción cerebro-intestino (trastornos funcionales digestivos): neuromoduladores en la práctica clínica (parte I)

Revista Colombiana de Gastroenterología
Introducción: en este artículo de revisión se desarrollan los principios básicos para el uso y los mecanismos de acción de los neuromoduladores utilizados en la práctica clínica y su papel en el tratamiento de los diferentes trastornos de la interacción
Luis Fernando Pineda Ovalle, David Benigno Páramo Hernández, Laura Marcela Moya Valenzuela, Alejandro Concha Mejía, Juan David Páramo Díaz   +4 more
doaj   +1 more source

Gauge-mediated supersymmetry breaking with generalized messenger sector at LHC [PDF]

, 2010
We consider the generalized gauge mediated supersymmetry breaking (GMSB) models with the messenger elds which do not form the complete multiplets of SU(5) GUT symmetry.
Kawase, H, Maekawa, N, Sakurai, K
core   +2 more sources

Gauge Coupling Unification in GUT with Anomalous U(1) Symmetry [PDF]

, 2002
We show that in the framework of grand unified theory (GUT) with anomalous $U(1)_A$ gauge symmetry, the success of the gauge coupling unification in the minimal SU(5) GUT is naturally explained, even if the mass spectrum of superheavy fields does not ...
C. D. Froggatt, C. H. Albright, E. Witten, J. J. Atick, J. L. Chkareuli, M. Bando, M. Bando, M. Bando, M. Dine, M. Dine, M. Green, M. Kakizaki, N. Maekawa, N. Maekawa, N. Maekawa, N. Maekawa, Nobuhiro Maekawa, Q. Shafi, Toshifumi Yamashita, Y. Kawamura, Y. Kawamura   +20 more
core   +2 more sources

Introduction to the human gut microbiota

Biochemical Journal, 2017
The human gastrointestinal (GI) tract harbours a complex and dynamic population of microorganisms, the gut microbiota, which exert a marked influence on the host during homeostasis and disease.
E. Thursby, N. Juge
semanticscholar   +1 more source

PD-1/PD-L1 Axis Downregulation in Guillain-Barré Syndrome: A Potential Mechanism Driving the Autoimmune Pathogenesis

International Journal of Infectious Diseases
Introduction: Guillain-Barré syndrome (GBS), an immune-mediated disorder of the peripheral nervous system characterized by progressive muscle weakness, is often triggered by Campylobacter jejuni infection. Molecular mimicry between C.
Mr Rasel Ahmed, Mrs Israt Jahan, Mrs Pritha Biswash, Miss Mehjabeen Haque, Miss Sarah Khurshid, Mr Jigishu Ahmed, Mr Sayed Akib Hossain, Dr Zhahirul Islam   +7 more
doaj   +1 more source

Ustawowe podstawy działania archiwów niemieckich. Federalne i krajowe ustawy archiwalne

Archeion, 2020
Statutory grounds for the activity of German archives. Federal and national laws on archives Laws on archives lay down the purposes and tasks of archives.
Gut, Paweł
doaj   +1 more source

Discrimination of Supersymmetric Grand Unified Models in Gaugino Mediation

, 2011
We consider supersymmetric grand unified theory (GUT) with the gaugino mediated supersymmetry breaking and investigate a possibility to discriminate different GUT models in terms of predicted sparticle mass spectra.
Okada, Nobuchika, Tran, Hieu Minh
core   +1 more source