Results 51 to 60 of about 172,085 (298)
Intestinal barrier function and absorption in pigs after waeaning: a review
, 2011 Under commercial conditions, weaning of piglets is associated with social, environmental and dietary stress. Consequently, small-intestinal barrier and absorptive functions deteriorate within a short time after weaning.
Wijtten, P.J.A. +2 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Protective Mechanism against Gut Barrier Dysfunction in Mesenteric Ischemia/Reperfusion
, 2012 Intestinal ischemia/reperfusion (I/R) results in mucosal barrier impairment and enhanced bacterial translocation (BT) into systemic circulation and extraintestinal visceral organs.
YU, LINDA CHIA-HUI, 余佳慧
core +1 more source
Frontiers in Immunology, 2019 The intestinal barrier provides the host with a strong defense line against the external environment playing also a pivotal role in the crosstalk between the gut microbiota and the immune system.
Martina Antonini +3 more
doaj +1 more source
Molecules, 2021 The gut epithelium is a mechanical barrier that protects the host from the luminal microenvironment and interacts with the gut microflora, which influences the development and progression of ulcerative colitis (UC).
Juan Zhang +7 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Bugs and the gut: breaking barriers to understanding [PDF]
Gut, 2001 See article on page 503 There has been a re-emergence of interest in the interplay between the faecal microbiota and its associated metabolisms and gastrointestinal function. This has recently been driven by the current interest in human and veterinary probiotics, and in the recent past by hypotheses which linked gut bacterial metabolism of ingested ...
openaire +2 more sources
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
, 2010 Background Although micronutrient supplementation can reduce morbidity and mortality due to diarrhoea, nutritional influences on intestinal host defence are poorly understood.
Sanderson, IR +20 more
core +1 more source
Polyphenols in Alzheimer’s Disease and in the Gut–Brain Axis
, 2020 Polyphenolic antioxidants, including dietary plant lignans, modulate the gut–brain axis, which involves transformation of these polyphenolic compounds into physiologically active and neuroprotector compounds (called human lignans) through gut ...
Prakash Reddy, V. +12 more
core +1 more source