Results 41 to 50 of about 172,085 (298)

Probiotic prophylaxis in predicted severe acute pancreatitis: a randomised, double-blind, placebo-controlled trial [PDF]

, 2008
: Background Infectious complications and associated mortality are a major concern in acute pancreatitis. Enteral administration of probiotics could prevent infectious complications, but convincing evidence is scarce. Our aim was to assess the effects of
van Eijck, Casper H. J., Rosman, Camiel, Schaapherder, Alexander F. M., Brink, M.A., van Ramshorst, B, Cuesta, Miguel A., van Santvoort, H.C., van Goor, H., Schaapherder, AFM, Besselink, Marc G. H., van der Harst, E, Cuesta, MA, Boermeester, Marja A., Boermeester, MA, van Eijck, CH, Witteman, Ben J. M., Schaapherder, A.F.M., Besselink, MGH, van der Harst, E., Akkermans, Louis M. A., van der Harst, Erwin, Buskens, E., Rosman, C., Dejong, C.H.C., Wahab, Peter J., Laarhoven, C.J.H.M. van, Nieuwenhuijs, V.B., Ploeg, RJ, Besselink, M.G.H., Witteman, BJM, Bollen, TL, Timmerman, Harro M., Timmerman, H.M., van Laarhoven, CJ, Ploeg, R.J., Dejong, CH, Buskens, Erik; id_orcid, Besselink, M.G., van Eijck, Casper, Van Eijck, GHJ, Timmerman, HM, Buskens, E, Gooszen, H.G., Van Laarhoven, CJHM, Akkermans, L.M., Grp, DAPS, Schaapherder, AF, Santvoort, H.C. van, Nieuwenhuijs, VB, Boermeester, M.A., Cuesta, M.A., Nieuwenhuijs, Vincent B., Bollen, T.L., Akkermans, LM, Wahab, PJ, Dejong, CHC, Gooszen, Hein G., van Ramshorst, B., Witteman, B.J., Akkermans, L.M.A., van Laarhoven, C.J.H.M., Dejong, C.H., Dejong, Cornelis H. C., Wahab, P.J., Eijck, C.H. van, van Laarhoven, C.J., Gooszen, HG, van der Harst, E (Erwin), Witteman, B.J.M., Bollen, Thomas L., Harst, E. van der, van Goor, H, Brink, M., van Ramshorst, Bert, Rosman, C, Buskens, Erik, van Laarhoven, Cees J. H. M., Brink, Menno A., Ramshorst, B. van, Ploeg, Rutger, van Goor, Harry, van Eijck, C.H.J., Goor, H. van, Besselink, MG, Brink, MA, Schaapherder, A.F., Akkermans, LMA, van Eijck, C.H., van Santvoort, HC, van Santvoort, Hjalmar C., Witteman, BJ, van Eijck, van, Ploeg, Rutger J.   +92 more
core   +1 more source

E-cigarettes compromise the gut barrier and trigger inflammation

iScience, 2021
Summary: E-cigarette usage continues to rise, yet the safety of e-cigarette aerosols is questioned. Using murine models of acute and chronic e-cigarette aerosol inhalation, murine colon transcriptomics, and murine and human gut-derived organoids in co ...
Aditi Sharma, Jasper Lee, Ayden G. Fonseca, Alex Moshensky, Taha Kothari, Ibrahim M. Sayed, Stella-Rita Ibeawuchi, Rama F. Pranadinata, Jason Ear, Debashis Sahoo, Laura E. Crotty-Alexander, Pradipta Ghosh, Soumita Das   +12 more
doaj   +1 more source

Role of Gut Barrier Function in the Pathogenesis of Nonalcoholic Fatty Liver Disease

Gastroenterology Research and Practice, 2015
Nonalcoholic fatty liver disease (NAFLD) is one of the most common forms of chronic liver disease, and its incidence is increasing year by year. Many efforts have been made to investigate the pathogenesis of this disease.
Xin Dai, Bangmao Wang
doaj   +1 more source

Comparison of Efavirenz and Dolutegravir on Gut Microbiome and Gut Barrier Functions. [PDF]

ACS Omega
Dolutegravir (DTG) is increasingly replacing efavirenz (EFV) as the recommended first-line antiretroviral therapy (cART) component due to its superior tolerance. However, both EFV-based and DTG-based cART regimens are associated with metabolic and neuropsychiatric disorders through mechanisms that remain poorly understood.
Huang YX, Tang Q, Fu SH, Zhong HJ, Liu Z, Zhong QY, Wang YH, Luo YD, Li XY, Chen S, Zhu HP.   +10 more
europepmc   +4 more sources

Salmonella transiently reside in luminal neutrophils in the inflamed gut. [PDF]

, 2012
Enteric pathogens need to grow efficiently in the gut lumen in order to cause disease and ensure transmission. The interior of the gut forms a complex environment comprising the mucosal surface area and the inner gut lumen with epithelial cell debris and
Mathias Heikenwalder (79126), Patrick Kaiser, Schubert Sören, Stecher, Bärbel, Wieser, Andreas, Kaiser, Patrick, Jette Lengefeld (172749), Schubert, Sören, Stecher, B., Andreas Wieser, Sören Schubert, Loetscher, Yvonne, Stecher Bärbel, Patrick Kaiser (172750), Wolf-Dietrich Hardt, Heikenwalder, Mathias, Lengefeld, J., Bärbel Stecher (78807), Jette Lengefeld, Schubert, S., Andreas Wieser (172747), Wieser Andreas, Loetscher, Y., Loetscher Yvonne, Wolf-Dietrich Hardt (46235), Lengefeld Jette, Heikenwälder, M., Yvonne Loetscher, Kaiser Patrick, Hardt Wolf-Dietrich, Wieser, A., Kaiser, P., Sören Schubert (172752), Bärbel Stecher, Heikenwalder Mathias, Hardt, W.D., Mathias Heikenwalder, Lengefeld, Jette, Hardt, Wolf-Dietrich; id_orcid, Yvonne Loetscher (172745), Hardt, Wolf-Dietrich   +40 more
core   +1 more source

Beyond allergic progression: From molecules to microbes as barrier modulators in the gut-lung axis functionality

, 2023
The “epithelial barrier hypothesis” states that a barrier dysfunction can result in allergy development due to tolerance breakdown. This barrier alteration may come from the direct contact of epithelial and immune cells with the allergens, and indirectly,
Turnay Abad, Francisco Javier, Batanero Cremades, Eva, García Gordo, Rubén, Villalba Díaz, María Teresa, Olmo López, Nieves, López Rodríguez, Juan Carlos, Parrón Ballesteros, Jorge   +6 more
core   +1 more source

Strain-specific effects of Akkermansia muciniphila on the regulation of intestinal barrier

Food Science and Human Wellness, 2023
Akkermansia muciniphila, one of the most promising next-generation probiotics, was reported to exhibit beneficial modulatory effects on the gut barrier.
Yang Liu, Qing Liu, Chengcheng Zhang, Jianxin Zhao, Hao Zhang, Wei Chen, Qixiao Zhai   +6 more
doaj   +1 more source

Crossing barriers: infections of the lung and the gut [PDF]

Mucosal Immunology, 2009
Although known as respiratory pathogens, severe acute respiratory syndrome (SARS) and its sister coronaviruses frequently cause enteric symptoms. In addition, other classically non-enteric viruses (such as HIV and influenza) may also have enteric effects that are crucial in their pathogeneses.
openaire   +3 more sources

Gut Microbiota and Immune System Interactions

, 2020
Dynamic interactions between gut microbiota and a host’s innate and adaptive immune systems are essential in maintaining intestinal homeostasis and inhibiting inflammation.
Maureen Groer, Anujit Sarkar, Ji Yoo, Samia Dutra, Daniel McSkimming   +4 more
core   +1 more source

Mesalazine in the initial management of severely acutely malnourished children with environmental enteric dysfunction : a pilot randomized controlled trial [PDF]

, 2014
Background: Environmental enteric dysfunction (EED) is an acquired syndrome of impaired gastrointestinal mucosal barrier function that is thought to play a key role in the pathogenesis of stunting in early life. It has been conceptualized as an adaptive
Simon H Murch, Hünten-Kirsch, B, Mulongo, MM, Mulongo, Musa M., Berkley, James, Laving, AM, Sullivan, Peter, Odera, D, Ahmed MR Laving, Berkley, J, Barbara Hünten-Kirsch, Hünten-Kirsch, Barbara, Caroline W Munyi, James A Berkley, Murch, SH, Mikusa, Jenifer, Sullivan, PB, Owino, Moses, Ngari, M, Dennis Odera, John O Warner, Sullivan, P, Fegan, G, Timbwa, Molline, Moses Owino, Mikusa, J, Nassir, HS, Munyi, Caroline W., H Samira Nassir, Berkley, James A., Laving, Ahmed M. R., Peter B Sullivan, Odera, Dennis, Ngari, Moses, Owino, M, Warner, JO, Jones, Kelsey D. J., Warner, J. O. (John O.), Musa M Mulongo, Jones, KDJ, Berkley, JA, Kelsey DJ Jones, Greg Fegan, Laving, AMR, Nassir, H. Samira, Huenten-Kirsch, B, Munyi, CW, Molline Timbwa, Sullivan, Peter B., Moses Ngari, Jenifer Mikusa, Timbwa, M, Fegan, Greg, Murch, Simon, Jones, KD   +54 more
core   +1 more source