Results 81 to 90 of about 12,827,422 (265)

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Optimisation of 16S rRNA gut microbiota profiling of extremely low birth weight infants

BMC Genomics, 2017
Background Infants born prematurely, particularly extremely low birth weight infants (ELBW) have altered gut microbial communities. Factors such as maternal health, gut immaturity, delivery mode, and antibiotic treatments are associated with microbiota ...
Cristina Alcon-Giner, Shabhonam Caim, Suparna Mitra, Jennifer Ketskemety, Udo Wegmann, John Wain, Gusztav Belteki, Paul Clarke, Lindsay J. Hall   +8 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Synergistic Effect of Microorganisms and Enzymes on Nutritional Value of Corn Stover and Wheat Straw

Fermentation
In this study, Candida utilis, Lactobacillus plantarum, and non-starch polysaccharide enzymes (cellulase, laccase, β-glucanase, xylanase, and mannanase) were employed to examine the effects of various microorganism–enzyme combinations on the nutritional ...
Binglong Chen, Jiancheng Liu, Mengjian Liu, Huiling Zhang, Xuanyue Li, Congcong Tian, Yong Chen   +6 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Development of the preterm gut microbiome in twins at risk of necrotising enterocolitis and sepsis [PDF]

, 2013
The preterm gut microbiome is a complex dynamic community influenced by genetic and environmental factors and is implicated in the pathogenesis of necrotising enterocolitis (NEC) and sepsis.
Christopher J Stewart, Berrington, Janet E., Andrew Nelson, Cummings Stephen P., Nelson Andrew, Stewart, Christopher, Janet E Berrington, Marrs, Emma, Stephen P Cummings, Embleton, Nicholas D., Janet E. Berrington (452418), Lanyon Clare, Stewart, Christopher J., Perry John D., Berrington, Janet, Stephen P. Cummings (106316), Cummings, Stephen, Emma C. L. Marrs (452415), Perry, John, Nicholas D. Embleton (177535), Embleton Nicholas D., Berrington Janet E., Nelson, Andrew, Cummings, Stephen P., Christopher J. Stewart (452414), Clare Lanyon (452416), Stewart Christopher J., Embleton, Nicholas, Andrew Nelson (209359), Perry, John D., Emma C L Marrs, John D Perry, Clare Lanyon, Marrs, Emma C.L., Lanyon, Clare, John D. Perry (452417), Nicholas D Embleton, Marrs Emma C. L.   +37 more
core   +1 more source

Consumers’ Perspectives and Experiences of Prebiotics and Probiotics for Gut Health in Chronic Kidney Disease

, 2022
Objectives: Nutrition supplementation, including prebiotics and probiotics, is a therapeutic strategy for modulating the gut microbiome in chronic kidney disease (CKD).
Kelly, JT, Conley, M, Johnson, DW, McFarlane, C, Campbell, KL, Jaimon T. Kelly, Katrina L. Campbell, Catherine McFarlane, David W. Johnson, Marguerite Conley   +9 more
core   +1 more source

Screening, Identification, and Whole-Genome Sequencing of Ferulic Acid Esterase-Producing Lactic Acid Bacteria from Sheep Rumen

Microorganisms
Ferulic acid esterase (FAE) plays an important role in plant fiber degradation by catalyzing the hydrolysis of lignocellulosic structures. FAE-producing lactic acid bacteria (LAB), as potential probiotics, can improve ruminant digestion and gut health ...
Mingxin Qiu, Yong Chen, Lei Wang, Luyu Li, Xiao Zhang, Zhuang Ma, Jiancheng Liu   +6 more
doaj   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source