Results 61 to 70 of about 872,080 (309)

Relationship between psychological state and level of activity of extrinsic gut innervation in patients with a functional gut disorder [PDF]

, 2001
Background: Anxiety and depression are known to be associated with alterations in central autonomic activity, and this may manifest as a functional gut disturbance.
Emmanuel, A.V., Kamm, M.A., Mason, H.J.
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The role of the mucin-glycan foraging Ruminococcus gnavus in the communication between the gut and the brain

Gut Microbes, 2022
Ruminococcus gnavus is a prevalent member of the human gut microbiota, which is over-represented in inflammatory bowel disease and neurological disorders. We previously showed that the ability of R.
Erika Coletto, Dimitrios Latousakis, Matthew G. Pontifex, Emmanuelle H. Crost, Laura Vaux, Estella Perez Santamarina, Andrew Goldson, Arlaine Brion, Mohammad K. Hajihosseini, David Vauzour, George M Savva, Nathalie Juge   +11 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The therapeutic management of gut barrier leaking: the emerging role for mucosal barrier protectors [PDF]

, 2015
OBJECTIVE: Gut barrier is a functional unit organized as a multi-layer system and its multiple functions are crucial for maintaining gut homeostasis. Numerous scientific evidences showed a significant association between gut barrier leaking and gastro ...
Bruno, G, Franceschi, F, Gasbarrini, A, Lopetuso, Lr, Petito, V, Scaldaferri, F   +5 more
core  

Health benefits and health claims of probiotics: bridging science and marketing [PDF]

, 2011
Health claims for probiotics are evaluated by the Panel on Dietetic Products, Nutrition and Allergies of the European Food Safety Authority. Despite a substantial amount of basic and clinical research on the beneficial effects of probiotics, all of the ...
Brummer, R.J., Rijkers, G.T., Vos, W.M., de   +2 more
core   +2 more sources

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Overweight and obesity are associated with colorectal neoplasia in an Australian outpatient population

Scientific Reports
Colorectal cancer is a major cause of cancer-related deaths within the Australian population. Colonoscopy and polypectomy represent effective forms of prevention.
Rina Kumar, Allison Brown, Satomi Okano, Lisa Simms, Anton Lord, Timothy O’Sullivan, Gunter Hartel, Graham L. Radford-Smith   +7 more
doaj   +1 more source

Bacterial chondronecrosis with osteomyelitis related Enterococcus cecorum isolates are genetically distinct from the commensal population and are more virulent in an embryo mortality model

Veterinary Research, 2023
Bacterial chondronecrosis with osteomyelitis (BCO) is a common cause of broiler lameness. Bacteria that are found in BCO lesions are intestinal bacteria that are proposed to have translocated through the intestinal epithelium and have spread systemically.
Yue Huang, Venessa Eeckhaut, Evy Goossens, Geertrui Rasschaert, Johan Van Erum, Geert Roovers, Richard Ducatelle, Gunther Antonissen, Filip Van Immerseel   +8 more
doaj   +1 more source

Acidification increases abundances of Vibrionales and Planctomycetia associated to a seaweed-grazer system: potential consequences for disease and prey digestion efficiency [PDF]

, 2018
Ocean acidification significantly affects marine organisms in several ways, with complex interactions. Seaweeds might benefit from rising CO2 through increased photosynthesis and carbon acquisition, with subsequent higher growth rates.
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core   +4 more sources