Results 91 to 100 of about 9,087 (209)
This review synthesises current knowledge on gut microbiome involvement in obesity and hypertension, evaluates microbiome‐based therapeutic strategies, and identifies critical research gaps to guide future investigations aimed at mitigating the dual pandemics.
Andrej Belančić +7 more
wiley +1 more source
Phage therapy: An alternative to antibiotics in the age of multi-drug resistance. [PDF]
The practice of phage therapy, which uses bacterial viruses (phages) to treat bacterial infections, has been around for almost a century. The universal decline in the effectiveness of antibiotics has generated renewed interest in revisiting this practice.
Koskella, Britt, Lin, Derek, Lin, Henry
core +1 more source
Gut virome in inflammatory bowel disease and beyond. [PDF]
ObjectiveThe gut virome is a dense community of viruses inhabiting the gastrointestinal tract and an integral part of the microbiota. The virome coexists with the other components of the microbiota and with the host in a dynamic equilibrium, serving as a key contributor to the maintenance of intestinal homeostasis and functions.
Tun HM +8 more
europepmc +3 more sources
Hi‐C sequencing was used to link viral sequences with microbial metagenome assembled genomes in the largely uncultivated waters of an oxygen‐deficient zone's secondary chlorophyll maximum within the Eastern Tropical North Pacific Ocean. ABSTRACT Oxygen‐deficient zones (ODZs) influence global nitrogen cycling as key sites for the removal of bioavailable
Christina Rathwell +2 more
wiley +1 more source
Eubiosis and dysbiosis: the two sides of the microbiota [PDF]
The microbial ecosystem of the gastrointestinal tract is characterized by a great number of microbial species living in balance by adopting mutualistic strategies. The eubiosis/dysbiosis condition of the gut microbiota strongly influences our healthy and
Cacciotti, Fatima +10 more
core
Speculations on the clinical significance of asymptomatic viral infections [PDF]
A detailed understanding of asymptomatic chronic viral infections is critical to analyse their pathogenesis, assess the severity and burden of disease and, where required, optimize public health control measures.
Gentile, Giuseppe, Micozzi, Alessandra
core +1 more source
Activity‐Informed Network Analysis Reveals Keystone Microbes Shaping Freshwater Ecosystem Function
Graphical abstract illustrating the workflow and key findings of this study. We first applied SPIEC‐EASI to metagenomic abundance data to construct microbial co‐occurrence networks and selected the top 15 MAGs based on degree centrality. We then used CARlasso to detect relationships between the top MAGs and environmental features.
Qiyao Yang +4 more
wiley +1 more source
Commentary : Bacteriophage transfer during faecal microbiota transplantation in Clostridium difficile infection is associated with treatment outcome [PDF]
Fecal microbiota transplantation (FMT) has been used as a treatmentof last resort for recurrent C. difficile infections (CDI) with a cure rate of 85–90% after the first FMT (van Nood et al., 2013; Jiang et al., 2017).
Anonye, Blessing
core +1 more source
Studying the gut virome in the metagenomic era: challenges and perspectives [PDF]
Abstract The human gut harbors a complex ecosystem of microorganisms, including bacteria and viruses. With the rise of next-generation sequencing technologies, we have seen a quantum leap in the study of human-gut-inhabiting bacteria, yet the viruses that infect these bacteria, known as bacteriophages, remain underexplored. In this review,
Garmaeva, Sanzhima +5 more
openaire +4 more sources
Viral Diversity of Coastal Restinga Soils From Southern Brazil
This study revealed high viral diversity in Restinga soils of southern Brazil, identifying over 6000 species (half unclassified) across 261 families. Dominant families included Mimiviridae, Phycodnaviridae, Peduoviridae and Kyanoviridae. While diversity was consistent among sites, urbanization and landscape isolation influenced viral richness and ...
Janaína Paula Back +10 more
wiley +1 more source

