Results 71 to 80 of about 5,749 (189)

Table_3_Alterations of the gut virome in patients with systemic lupus erythematosus.xlsx

, 2023
BackgroundSystemic lupus erythematosus (SLE) is a systemic autoimmune disease that has been linked to the dysbiosis of the gut microbiome and virome.
Xueming Yao (6517202), Dan Zhu (139675), Zhengqi Liu (5947079), Ying Huang (53474), Qiongyu Zhang (13451737), Qingbo Lv (11631289), Hufan Li (14377224), Qiulong Yan (4522912), Guangyang Wang (3001269), Can Liu (205007), Yue Zhang (30585), Changming Chen (275732), Jing Zhou (168494), Qin Zhong (566779), Aiqin Zhang (620075), Wukai Ma (10939086), Yang An (326217), Shenghui Li (432673), Fang Tang (116243), Wen Sun (273647), Hayan Ullah (14377221)   +20 more
core   +1 more source

Multi‐omics biomarkers for intestinal infection and inflammation in inflammatory bowel disease: Current evidence, translational challenges, and diagnostic opportunities

Interdisciplinary Medicine, EarlyView.
Prospective multi‐site cohorts, multi‐omics profiling, and computational analysis may help identify biomarker patterns across clinical settings in IBD and superimposed infections. With further mechanistic and clinical validation, these signals could support the development of practical multi‐analyte tools for more precise diagnosis and management ...
Ziyu Yang, Jiayi Yao, Xinxian Zhao, Yan Xu, Yifan Chen, Tianchi Chen, Ying Jian, Min Li   +7 more
wiley   +1 more source

Distinct gut virome profile of pregnant women with type 1 diabetes in the ENDIA study [PDF]

, 2019
Background:The importance of gut bacteria in human physiology, immune regulation, and disease pathogenesis is well established. In contrast, the composition and dynamics of the gut virome are largely unknown; particularly lacking are studies in pregnancy.
Harris, M., Isaacs, S.R., Harrison, L.C., Morahan, G., Lipkin, W.I., Horton, J.L., Morbey, C., Haynes, A., Barry, S.C., Papenfuss, A.T., Wook Kim, K., Couper, J.J., Colman, P.G., Jain, K., Davis, E.A., Giles, L.C., Briese, T., Allen, D.W., Pang, I.C.N., Cotterill, A.M., et al.   +20 more
core   +4 more sources

Metabolic Dysfunction‐Associated Steatotic Liver Disease and Obesity: Pathogenesis, Diagnostics, Risk Stratification, and Therapeutic Approach

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) has emerged as the most prevalent chronic liver disease worldwide, closely linked to the global rising incidence of obesity and metabolic syndrome. This review synthesizes current evidence on the pathogenesis, gut–liver axis, and multidisciplinary management of MASLD within the ...
Beom Kyung Kim
wiley   +1 more source

From HBV to MASLD Cirrhosis: Mechanistic Insights and Therapeutic Strategies

Portal Hypertension &Cirrhosis, EarlyView.
This review examines the epidemiological shift from hepatitis B virus (HBV) to metabolic dysfunction‐associated steatotic liver disease (MASLD) as the leading cause of cirrhosis globally. It highlights the distinct pathogenic mechanisms between HBV and MASLD cirrhosis and discusses evolving diagnostic tools and therapeutic strategies tailored to the ...
Hanqi Yu, Hongfan Ding, Yang Huang, Haoze Cao, Yuan Ding, Weilin Wang   +5 more
wiley   +1 more source

Transmission and dynamics of mother-infant gut viruses during pregnancy and early life

Nature Communications
Early development of the gut ecosystem is crucial for lifelong health. While infant gut bacterial communities have been studied extensively, the infant gut virome remains under-explored. To study the development of the infant gut virome over time and the
Sanzhima Garmaeva, Trishla Sinha, Anastasia Gulyaeva, Nataliia Kuzub, Johanne E. Spreckels, Sergio Andreu-Sánchez, Ranko Gacesa, Arnau Vich Vila, Siobhan Brushett, Marloes Kruk, Lifelines NEXT cohort study, Jackie Dekens, Jan Sikkema, Folkert Kuipers, Andrey N. Shkoporov, Colin Hill, Sicco Scherjon, Cisca Wijmenga, Jingyuan Fu, Alexander Kurilshikov, Alexandra Zhernakova   +20 more
doaj   +1 more source

Validation and development of sequence-based tools to analyse the human gut virome [PDF]

, 2019
The gut microbiome is a complex community of microorganisms that interacts closely with the human host and is believed to play an important role in the maintenance of human health.
Sutton, Thomas D. S.
core  

Gut Virome: Role and Distribution in Health and Gastrointestinal Diseases

, 2022
The study of the intestinal microbiome is an evolving field of research that includes comprehensive analysis of the vast array of microbes – bacterial, archaeal, fungal, and viral.
Olawuni, Babatunde, Spencer, Laurie, Singh, Pallavi   +2 more
core   +1 more source

Uric Acid in Metabolic Dysfunction‐Associated Steatotic Liver Disease

Portal Hypertension &Cirrhosis, EarlyView.
MASLD is the most prevalent chronic liver disease worldwide, yet effective pharmacological treatments remain limited. Hyperuricemia is now recognized as a key driver of hepatic steatosis, inflammation, and fibrosis, with elevated serum uric acid levels independently predicting hepatocellular carcinoma and liver‐related mortality.
Rong Wang, Zhenyu Liu, Jun Lin, Weijing Zhang, Xianzhi Liu, Tong Zhang   +5 more
wiley   +1 more source

Iflaviruses in arthropods: when small is mighty

Insect Science, EarlyView.
Many arthropod species harbor iflaviruses, which often cause covert (asymptomatic) infections, but may still affect host fitness. We review the impact of iflaviruses on arthropod fitness, immunity, behaviour as well as the iflavirus’ host range, transmission, tissue tropism and the interactions with other microorganisms within arthropods.
Annamaria Mattia, Hannah‐Isadora Huditz, Monique M. van Oers, Vera I.D. Ros   +3 more
wiley   +1 more source