Results 51 to 60 of about 372,196 (191)

The human gut virome: Composition, colonisation, interactions, and impacts on human health

, 2022
The gut virome is an incredibly complex part of the gut ecosystem. Gut viruses play a role in many disease 9 states, but it is not yet known to what extent the gut virome impacts everyday human health. New 10 experimental and bioinformatic approaches are
Sarah Giles, Michael Roach, Amber Skye, Robert Edwards, Evan Pargin   +4 more
core   +1 more source

Expanding the Role of the Virome: Commensalism in the Gut [PDF]

Journal of Virology, 2015
ABSTRACT Viruses affect host physiology beyond causing acute disease, thereby giving rise to the concept that the virome is a component of the microbiome. However, the role of the enteric virome is understudied relative to the fast-paced research examining commensal bacteria in the intestine.
openaire   +2 more sources

Fecal Virome Transplantation in Human Disease and Livestock Production: Evidence, Mechanisms, and Translational Challenges

Animal Research and One Health, EarlyView.
Fecal virome transplantation may reshape bacterial communities and host responses while reducing viable bacterial transfer. Preclinical evidence suggests biological activity, but human efficacy remains uncertain, and translation requires product standardization, causal validation, donor–recipient matching, and rigorous biosafety assessment.
Luanyang Shi, Yongjuan Guan, Guanxiang Liang   +2 more
wiley   +1 more source

The human gut virome database [PDF]

, 2019
ABSTRACT The gut microbiome profoundly impacts human health and disease, but viruses that infect these microbes are likely also important. Problematically, viral sequences are often missed due to insufficient reference viral genomes. Here we (i) built a human gut virome database, GVD, from 648 viral particle metagenomes or microbial ...
Gregory, Ann C., Zablocki, Olivier, Howell, Allison, Bolduc, Benjamin, Sullivan, Matthew B.   +4 more
openaire   +1 more source

Gut virome in inflammatory bowel disease and beyond

Gut, 2023
Objective The gut virome is a dense community of viruses inhabiting the gastrointestinal tract and an integral part of the microbiota. The virome coexists with the other components of the microbiota and with the host in a dynamic equilibrium, serving as a key contributor to the maintenance of intestinal ...
Hein Min Tun, Ye Peng, Luca Massimino, Zhen Ye Sin, Tommaso Lorenzo Parigi, Amanda Facoetti, Shaila Rahman, Silvio Danese, Federica Ungaro   +8 more
openaire   +2 more sources

Metabolic Dysfunction‐Associated Steatotic Liver Disease and Obesity: Pathogenesis, Diagnostics, Risk Stratification, and Therapeutic Approach

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) has emerged as the most prevalent chronic liver disease worldwide, closely linked to the global rising incidence of obesity and metabolic syndrome. This review synthesizes current evidence on the pathogenesis, gut–liver axis, and multidisciplinary management of MASLD within the ...
Beom Kyung Kim
wiley   +1 more source

The Kenyan Human Gut Virome Catalogue reveals extensive viral diversity and age-dependent community structure

Scientific Reports
The human gut virome is a critical yet understudied component of the microbiome that shapes microbial community structure and host-microbe interactions. However, most existing human gut virome reference databases have been constructed predominantly from ...
Simeon Nthuku, James Mordecai, Abiola A. Babajide, David Makoko, Yacouba Sawadogo, Olaitan I. Awe   +5 more
doaj   +1 more source

Gut virome alterations in patients with chronic obstructive pulmonary disease

Microbiology Spectrum
Chronic obstructive pulmonary disease (COPD) is one of the primary causes of mortality and morbidity worldwide. The gut microbiome, particularly the bacteriome, has been demonstrated to contribute to the progression of COPD. However, the influence of gut
Yue Liu, Qingsong Huang, Zhenhua Zhuang, Hongjing Yang, Xiaoling Gou, Tong Xu, Ke Liu, Jun Wang, Bo Liu, Peiyang Gao, Feng Cao, Bin Yang, Chuantao Zhang, Mei Chen, Gang Fan   +14 more
doaj   +1 more source

A Previously Undescribed Highly Prevalent Phage Identified in a Danish Enteric Virome Catalog

mSystems, 2021
Gut viruses are important, yet often neglected, players in the complex human gut microbial ecosystem. Recently, the number of human gut virome studies has been increasing; however, we are still only scratching the surface of the immense viral diversity ...
Lore Van Espen, Emilie Glad Bak, Leen Beller, Lila Close, Ward Deboutte, Helene Bæk Juel, Trine Nielsen, Deniz Sinar, Lander De Coninck, Christine Frithioff-Bøjsøe, Cilius Esmann Fonvig, Suganya Jacobsen, Maria Kjærgaard, Maja Thiele, Anthony Fullam, Michael Kuhn, Jens-Christian Holm, Peer Bork, Aleksander Krag, Torben Hansen, Manimozhiyan Arumugam, Jelle Matthijnssens   +21 more
doaj   +1 more source

Microbiota as the candidate biomarker in pediatric obstructive sleep apnea

Sleep Research, EarlyView.
Abstract Pediatric obstructive sleep apnea (OSA) is a form of sleep‐disordered breathing in children. Recent studies have focused on characterizing microbiota alterations associated with pediatric OSA and identifying microbial features that may have potential value as future biomarkers. The most commonly used approach for microbiota profiling is second‐
Xiaoyan Li, Jingxuan Bai, Ying Xu, Min Yu, Xuemei Gao   +4 more
wiley   +1 more source