Results 31 to 40 of about 9,087 (209)
The human gut virome: form and function [PDF]
Emerging Topics in Life Sciences, 2017 Advances in next-generation sequencing technologies and the application of metagenomic approaches have fuelled an exponential increase in our understanding of the human gut microbiome. These approaches are now also illuminating features of the diverse and abundant collection of viruses (termed the virome) subsisting with the microbial ecosystems ...
Ogilvie, Lesley, Jones, Brian
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Altered human gut virome in patients undergoing antibiotics therapy for Helicobacter pylori
Nature Communications, 2023 Transient gut microbiota alterations have been reported after antibiotic therapy for Helicobacter pylori. However, alteration in the gut virome after H. pylori eradication remains uncertain. Here, we apply metagenomic sequencing to fecal samples of 44 H.
Lingling Wang +6 more
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Comparative analysis of gut DNA viromes in wild and captive Himalayan vultures
Frontiers in Microbiology, 2023 IntroductionHimalayan vultures (Gyps hinalayensis) are widely distributed on the Qinghai-Tibetan Plateau and play a crucial role in maintaining the ecological balance by feeding on decayed corpses of wild and domestic animals.
Jundie Zhai +20 more
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Gut as viral reservoir: lessons from gut viromes, HIV and COVID-19 [PDF]
Gut, 2021 The gut microbiota is composed of bacteria, fungi and viruses.1–3 While the presence and composition of the bacteriome have been extensively studied in recent years, the ‘dark matter’ of microbiomes including viruses (viral microbiome or virome) remains incompletely understood.4 Analysis of microbiotic communities in the gut showed that bacteria ...
Markus F Neurath +2 more
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Gut mucosal virome alterations in ulcerative colitis [PDF]
Gut, 2019 Objective The pathogenesis of UC relates to gut microbiota dysbiosis. We postulate that alterations in the viral community populating the intestinal mucosa play an important role in UC pathogenesis. This study aims to characterise the mucosal virome and their functions in health and UC.
Tao Zuo +15 more
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Frontiers in Microbiology, 2022 Depression is a heterogeneous mental disorder that has been linked to disturbances in the gut microbiome. As an essential part of the gut microbiome, gut virome may play critical roles in disease progression and development.
Jiajia Duan +4 more
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The human gut virome: a multifaceted majority [PDF]
Frontiers in Microbiology, 2015 Here, we outline our current understanding of the human gut virome, in particular the phage component of this ecosystem, highlighting progress, and challenges in viral discovery in this arena. We reveal how developments in high-throughput sequencing technologies and associated data analysis methodologies are helping to illuminate this abundant ...
Lesley Ann Ogilvie +3 more
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Molecular bases and role of viruses in the human microbiome. [PDF]
, 2014 Viruses are dependent biological entities that interact with the genetic material of most cells on the planet, including the trillions within the human microbiome.
Abeles, Shira R, Pride, David T
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Rapid evolution of the human gut virome [PDF]
Proceedings of the National Academy of Sciences, 2013 Humans are colonized by immense populations of viruses, which metagenomic analysis shows are mostly unique to each individual. To investigate the origin and evolution of the human gut virome, we analyzed the viral community of one adult individual over 2.5 y by extremely deep metagenomic sequencing (56 billion bases of purified viral ...
Samuel, Minot +5 more
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Metagenomic-based characterization of the gut virome in patients with polycystic ovary syndrome
Frontiers in Microbiology, 2022 BackgroundPolycystic ovary syndrome (PCOS) is a complex disease that afflicts women of reproductive age, and its pathological mechanism has not been well explained. The gut microbiota is believed to be closely related to the development of PCOS. Although
Liansha Huang +9 more
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