Results 31 to 40 of about 5,207 (162)
Frontiers in Microbiology, 2022 Depression is a heterogeneous mental disorder that has been linked to disturbances in the gut microbiome. As an essential part of the gut microbiome, gut virome may play critical roles in disease progression and development.
Jiajia Duan +4 more
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Metagenomic-based characterization of the gut virome in patients with polycystic ovary syndrome
Frontiers in Microbiology, 2022 BackgroundPolycystic ovary syndrome (PCOS) is a complex disease that afflicts women of reproductive age, and its pathological mechanism has not been well explained. The gut microbiota is believed to be closely related to the development of PCOS. Although
Liansha Huang +9 more
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Hypervariable loci in the human gut virome [PDF]
Proceedings of the National Academy of Sciences, 2012 Genetic variation is critical in microbial immune evasion and drug resistance, but variation has rarely been studied in complex heterogeneous communities such as the human microbiome. To begin to study natural variation, we analyzed DNA viruses present in the lower gastrointestinal tract of 12 human volunteers by determining 48 billion bases of viral ...
Samuel, Minot +4 more
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The gut virome in two indigenous populations from Malaysia
Scientific Reports, 2022 The human gut contains a complex microbiota dominated by bacteriophages but also containing other viruses and bacteria and fungi. There are a growing number of techniques for the extraction, sequencing, and analysis of the virome but currently no ...
Chuen Zhang Lee +6 more
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Viral metagenomics of the gut virome of diarrheal children with Rotavirus A infection
Gut Microbes, 2023 Diarrhea is a leading cause of morbidity and mortality in children worldwide and represents a major dysbiosis event. Rotavirus has been recognized as a global leading pathogen of diarrhea.
Siwen Bao +16 more
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Putting the Virome on the Map: The Influence of Host Geography and Ethnicity on the Gut Virome [PDF]
Cell Host & Microbe, 2020 We know little about factors that ordain the composition of the diverse community of viruses (virome) in the human gut. In this issue of Cell Host & Microbe, Zuo et al. highlight the importance of geography, urbanization, ethnicity, and diet on the shape of the adult gut DNA virome.
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The gut virome in association with the bacteriome in gastrointestinal diseases and beyond: roles, mechanisms, and clinical applications [PDF]
Precision Clinical MedicineAnna Philips, Tao Zuo, Philips Anna
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Studying the gut virome in the metagenomic era: challenges and perspectives [PDF]
BMC Biology, 2019 Abstract The human gut harbors a complex ecosystem of microorganisms, including bacteria and viruses. With the rise of next-generation sequencing technologies, we have seen a quantum leap in the study of human-gut-inhabiting bacteria, yet the viruses that infect these bacteria, known as bacteriophages, remain underexplored. In this review,
Garmaeva, Sanzhima +5 more
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Gut mucosal virome alterations in ulcerative colitis [PDF]
Gut, 2019 Objective The pathogenesis of UC relates to gut microbiota dysbiosis. We postulate that alterations in the viral community populating the intestinal mucosa play an important role in UC pathogenesis. This study aims to characterise the mucosal virome and their functions in health and UC.
Tao Zuo +15 more
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Characteristics of the tree shrew gut virome
PLOS ONE, 2019 The tree shrew (Tupaia belangeri) has been proposed as an alternative laboratory animal to primates in biomedical research in recent years. However, characteristics of the tree shrew gut virome remain unclear. In this study, the metagenomic analysis method was used to identify the features of gut virome from fecal samples of this animal. Results showed
Linxia Chen +11 more
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