Results 41 to 50 of about 5,207 (162)

Gut virome profile in healthy Saudi children

Saudi Journal of Gastroenterology, 2023
Background: The role of viruses is well known in health and disease. The aim of this report was to describe the profile of viruses in the gut of healthy Saudi children. Methods: In 20 randomly selected school age children from Riyadh, stool samples were collected in cryovials and ...
Mohammad I. El Mouzan, Asaad A. Assiri, Ahmed A. Al Sarkhy, Mona M. Alasmi   +3 more
openaire   +3 more sources

Dynamic changes occur in the DNA gut virome of female cynomolgus macaques during aging

MicrobiologyOpen, 2021
Aging is a critical factor affecting physical health and disease in mammals. Emerging evidence indicates that aging may affect the gut bacteriome in cynomolgus macaques, but little is known about whether or how the gut virome changes with age.
Xunmin Tan, Tingjia Chai, Jiajia Duan, Jing Wu, Hanping Zhang, Yifan Li, Yu Huang, Xi Hu, Peng Zheng, Jinlin Song, Ping Ji, Xin Jin, Hongmei Zhang, Peng Xie   +13 more
doaj   +1 more source

Gut virome in inflammatory bowel disease and beyond

Gut, 2023
Objective The gut virome is a dense community of viruses inhabiting the gastrointestinal tract and an integral part of the microbiota. The virome coexists with the other components of the microbiota and with the host in a dynamic equilibrium, serving as a key contributor to the maintenance of intestinal ...
Hein Min Tun, Ye Peng, Luca Massimino, Zhen Ye Sin, Tommaso Lorenzo Parigi, Amanda Facoetti, Shaila Rahman, Silvio Danese, Federica Ungaro   +8 more
openaire   +2 more sources

The human gut virome database [PDF]

, 2019
ABSTRACT The gut microbiome profoundly impacts human health and disease, but viruses that infect these microbes are likely also important. Problematically, viral sequences are often missed due to insufficient reference viral genomes. Here we (i) built a human gut virome database, GVD, from 648 viral particle metagenomes or microbial ...
Gregory, Ann C., Zablocki, Olivier, Howell, Allison, Bolduc, Benjamin, Sullivan, Matthew B.   +4 more
openaire   +1 more source

Alterations in the gut virome in patients with ankylosing spondylitis

Frontiers in Immunology, 2023
IntroductionAnkylosing spondylitis (AS), a chronic autoimmune disease, has been linked to the gut bacteriome.MethodsTo investigate the characteristics of the gut virome in AS, we profiled the gut viral community of 193 AS patients and 59 healthy subjects based on a metagenome-wide analysis of fecal metagenomes from two publicly available datasets ...
Chen Li, Yan Zhang, Qiulong Yan, Ruochun Guo, Changming Chen, Shenghui Li, Yue Zhang, Jinxin Meng, Jie Ma, Wei You, Zhisong Wu, Wen Sun, Wen Sun, Wen Sun   +13 more
openaire   +3 more sources

Expanding the Role of the Virome: Commensalism in the Gut [PDF]

Journal of Virology, 2015
ABSTRACT Viruses affect host physiology beyond causing acute disease, thereby giving rise to the concept that the virome is a component of the microbiome. However, the role of the enteric virome is understudied relative to the fast-paced research examining commensal bacteria in the intestine.
openaire   +2 more sources

A Previously Undescribed Highly Prevalent Phage Identified in a Danish Enteric Virome Catalog

mSystems, 2021
Gut viruses are important, yet often neglected, players in the complex human gut microbial ecosystem. Recently, the number of human gut virome studies has been increasing; however, we are still only scratching the surface of the immense viral diversity ...
Lore Van Espen, Emilie Glad Bak, Leen Beller, Lila Close, Ward Deboutte, Helene Bæk Juel, Trine Nielsen, Deniz Sinar, Lander De Coninck, Christine Frithioff-Bøjsøe, Cilius Esmann Fonvig, Suganya Jacobsen, Maria Kjærgaard, Maja Thiele, Anthony Fullam, Michael Kuhn, Jens-Christian Holm, Peer Bork, Aleksander Krag, Torben Hansen, Manimozhiyan Arumugam, Jelle Matthijnssens   +21 more
doaj   +1 more source

A Comprehensive Microbial Gene Catalog of the Human Airway Microbiome Across Anatomical Sites and Geographic Regions

Advanced Science, EarlyView.
An integrated Human Airway Microbiome Gene Catalog (iHAMGC) is constructed from 12,273 metagenomic airway samples, providing a high‐resolution reference of respiratory microbial genes. The catalog enables systematic exploration of taxonomic and functional variation across airway niches and geographic regions, revealing site‐specific and region ...
Qing Zhang, Dashu Li, Bo Liu, Yue Zhang, Min Li, Ruochun Guo, Yawen Ni, Shibin Chen, Biao Ni, Lijie Qiu, Guorui Xing, He Dong, Qiulong Yan, Shenghui Li, Xiaohui Zou, Bin Cao   +15 more
wiley   +1 more source

Fecal Microbiota Transplantation and Microbiota‐Based Therapeutics in Allogeneic Hematopoietic Stem Cell Transplantation: Current Evidence and Future Directions

Clinical Pharmacology &Therapeutics, EarlyView.
The intestinal microbiome is a key regulator of immune homeostasis, metabolism, and epithelial barrier integrity. In patients with malignant hematological diseases, particularly those undergoing hematopoietic stem cell transplantation, microbiome perturbations by reduced diversity, pathobiont expansion, and loss of beneficial metabolites are common as ...
Bálint Gergely Szabó, Dorina Korózs, Michal Bator, Krisztina Jeszenszky, Viktor Lakatos, László Gopcsa, Péter Reményi, János Sinkó   +7 more
wiley   +1 more source

Diversity and potential function of pig gut DNA viruses

Heliyon, 2023
Viruses are ubiquitous in the gut of animals and play an important role in the ecology of the gut microbiome. The potential effects of these substances on the growth and development of the body are not fully known.
Junjun Qin, Bingzhen Ji, Yijia Ma, Xin Liu, Tian Wang, Guiming Liu, Bugao Li, Guoliang Wang, Pengfei Gao   +8 more
doaj   +1 more source