Results 41 to 50 of about 9,087 (209)
The human gut virome database [PDF]
ABSTRACTThe gut microbiome profoundly impacts human health and disease, but viruses that infect these microbes are likely also important. Problematically, viral sequences are often missed due to insufficient reference viral genomes. Here we (i) built a human gut virome database, GVD, from 648 viral particle metagenomes or microbial metagenomes from 572
Gregory, Ann C. +4 more
openaire +1 more source
Hypervariable loci in the human gut virome [PDF]
Genetic variation is critical in microbial immune evasion and drug resistance, but variation has rarely been studied in complex heterogeneous communities such as the human microbiome. To begin to study natural variation, we analyzed DNA viruses present in the lower gastrointestinal tract of 12 human volunteers by determining 48 billion bases of viral ...
Samuel, Minot +4 more
openaire +2 more sources
Transmission of viruses via our microbiomes. [PDF]
BackgroundBacteria inhabiting the human body have important roles in a number of physiological processes and are known to be shared amongst genetically-related individuals.
Abeles, Shira R +7 more
core +1 more source
Phages and human health: More than idle hitchhikers [PDF]
Bacteriophages, or phages, are viruses that infect bacteria and archaea. Phages have diverse morphologies and can be coded in DNA or RNA and as single or double strands with a large range of genome sizes. With the increasing use of metagenomic sequencing
Baldridge, Megan T +2 more
core +2 more sources
Fecal Viral Community Responses to High-Fat Diet in Mice. [PDF]
Alterations in diet can have significant impact on the host, with high-fat diet (HFD) leading to obesity, diabetes, and inflammation of the gut.
Blaser, Martin J +6 more
core +1 more source
Viral metagenomics of the gut virome of diarrheal children with Rotavirus A infection
Diarrhea is a leading cause of morbidity and mortality in children worldwide and represents a major dysbiosis event. Rotavirus has been recognized as a global leading pathogen of diarrhea.
Siwen Bao +16 more
doaj +1 more source
ΦCrAss001 represents the most abundant bacteriophage family in the human gut and infects Bacteroides intestinalis [PDF]
peer-reviewedCrAssphages are an extensive and ubiquitous family of tailed bacteriophages, predicted to infect bacteria of the order Bacteroidales. Despite being found in ~50% of individuals and representing up to 90% of human gut viromes, members of this
Draper, Lorraine A. +6 more
core +5 more sources
454-Pyrosequencing: A Molecular Battiscope for Freshwater Viral Ecology [PDF]
Viruses, the most abundant biological entities on the planet, are capable of infecting organisms from all three branches of life, although the majority infect bacteria where the greatest degree of cellular diversity lies.
Ackermann +13 more
core +3 more sources
Urinary virome perturbations in kidney transplantation [PDF]
The human microbiome is important for health and plays a role in essential metabolic functions and protection from certain pathogens. Conversely, dysbiosis of the microbiome is seen in the context of various diseases. Recent studies have highlighted that
Carrie D. Nicora +7 more
core +9 more sources
Does the Human Gut Virome Contribute to Host Health or Disease?
The human gastrointestinal (GI) tract harbors eukaryotic and prokaryotic viruses and their genomes, metabolites, and proteins, collectively known as the “gut virome”.
Grazia Pavia +3 more
doaj +1 more source

