Results 61 to 70 of about 5,749 (189)

The human gut virome database [PDF]

, 2019
ABSTRACT The gut microbiome profoundly impacts human health and disease, but viruses that infect these microbes are likely also important. Problematically, viral sequences are often missed due to insufficient reference viral genomes. Here we (i) built a human gut virome database, GVD, from 648 viral particle metagenomes or microbial ...
Gregory, Ann C., Zablocki, Olivier, Howell, Allison, Bolduc, Benjamin, Sullivan, Matthew B.   +4 more
openaire   +1 more source

Alterations in the gut virome in patients with ankylosing spondylitis

Frontiers in Immunology, 2023
IntroductionAnkylosing spondylitis (AS), a chronic autoimmune disease, has been linked to the gut bacteriome.MethodsTo investigate the characteristics of the gut virome in AS, we profiled the gut viral community of 193 AS patients and 59 healthy subjects based on a metagenome-wide analysis of fecal metagenomes from two publicly available datasets ...
Chen Li, Yan Zhang, Qiulong Yan, Ruochun Guo, Changming Chen, Shenghui Li, Yue Zhang, Jinxin Meng, Jie Ma, Wei You, Zhisong Wu, Wen Sun, Wen Sun, Wen Sun   +13 more
openaire   +3 more sources

A Previously Undescribed Highly Prevalent Phage Identified in a Danish Enteric Virome Catalog

mSystems, 2021
Gut viruses are important, yet often neglected, players in the complex human gut microbial ecosystem. Recently, the number of human gut virome studies has been increasing; however, we are still only scratching the surface of the immense viral diversity ...
Lore Van Espen, Emilie Glad Bak, Leen Beller, Lila Close, Ward Deboutte, Helene Bæk Juel, Trine Nielsen, Deniz Sinar, Lander De Coninck, Christine Frithioff-Bøjsøe, Cilius Esmann Fonvig, Suganya Jacobsen, Maria Kjærgaard, Maja Thiele, Anthony Fullam, Michael Kuhn, Jens-Christian Holm, Peer Bork, Aleksander Krag, Torben Hansen, Manimozhiyan Arumugam, Jelle Matthijnssens   +21 more
doaj   +1 more source

Integrated gut virome and bacteriome dynamics in COVID-19 patients

, 2021
SARS-CoV-2 is the cause of the current global pandemic of COVID-19; this virus infects multiple organs, such as the lungs and gastrointestinal tract. The microbiome in these organs, including the bacteriome and virome, responds to infection and might ...
Fanping Meng, Jin Yan, Jingjing Lu, Kun Xu, Changqing Bai, Jiabao Cao, Shaogeng Zhang, Lianpan Dai, Linxiang Yu, Na Zhao, Jun Wang, Penghui Yang, Cheng Wang, Yi Shi, Yuhai Bi, Yuhuan Gong, Ning Zhang, Zhu Chen, Yuqing Zhang, Guanglin Lei   +19 more
core   +1 more source

Expanding the Role of the Virome: Commensalism in the Gut [PDF]

Journal of Virology, 2015
ABSTRACT Viruses affect host physiology beyond causing acute disease, thereby giving rise to the concept that the virome is a component of the microbiome. However, the role of the enteric virome is understudied relative to the fast-paced research examining commensal bacteria in the intestine.
openaire   +2 more sources

Gut virome alterations in patients with chronic obstructive pulmonary disease

Microbiology Spectrum
Chronic obstructive pulmonary disease (COPD) is one of the primary causes of mortality and morbidity worldwide. The gut microbiome, particularly the bacteriome, has been demonstrated to contribute to the progression of COPD. However, the influence of gut
Yue Liu, Qingsong Huang, Zhenhua Zhuang, Hongjing Yang, Xiaoling Gou, Tong Xu, Ke Liu, Jun Wang, Bo Liu, Peiyang Gao, Feng Cao, Bin Yang, Chuantao Zhang, Mei Chen, Gang Fan   +14 more
doaj   +1 more source

Table_2_Alterations of the gut virome in patients with systemic lupus erythematosus.xlsx

, 2023
BackgroundSystemic lupus erythematosus (SLE) is a systemic autoimmune disease that has been linked to the dysbiosis of the gut microbiome and virome.
Xueming Yao (6517202), Dan Zhu (139675), Zhengqi Liu (5947079), Ying Huang (53474), Qiongyu Zhang (13451737), Qingbo Lv (11631289), Hufan Li (14377224), Qiulong Yan (4522912), Guangyang Wang (3001269), Can Liu (205007), Yue Zhang (30585), Changming Chen (275732), Jing Zhou (168494), Qin Zhong (566779), Aiqin Zhang (620075), Wukai Ma (10939086), Yang An (326217), Shenghui Li (432673), Fang Tang (116243), Wen Sun (273647), Hayan Ullah (14377221)   +20 more
core   +1 more source

The gut virome and the relevance of temperate phages in human health [PDF]

, 2023
Alterations in the gut virome impact human health. Bacteriophages, viruses that infect bacteria, dominate the gut virome and are mainly composed by virulent and temperate phages. While virulent phages exclusively replicate within and lyse their bacterial
Jeremy J. Barr, Sofia Dahlman, Laura Avellaneda-Franco   +2 more
core   +1 more source

Shotgun Metagenomic Profiling of the Gut Virome in Prodromal and Confirmed Parkinson's Disease

Annals of Neurology, EarlyView.
We conducted a nested case‐control study within the Nurses’ Health Study and the Health Professionals Follow‐up Study to examine the role of the gut virome (GV) in Parkinson's disease (PD). We applied a novel metagenomic virome profiling approach, Bioinformatic Application for Quantification and Labeling of Viral taxonomy (BAQLaVa), to prospectively ...
Deepika Dinesh, Xochitl C. Morgan, Jordan Jensen, Kjetil Bjornevik, Michael A. Schwarzschild, Alberto Ascherio, Curtis Huttenhower, Natalia Palacios   +7 more
wiley   +1 more source

Diversity and potential function of pig gut DNA viruses

Heliyon, 2023
Viruses are ubiquitous in the gut of animals and play an important role in the ecology of the gut microbiome. The potential effects of these substances on the growth and development of the body are not fully known.
Junjun Qin, Bingzhen Ji, Yijia Ma, Xin Liu, Tian Wang, Guiming Liu, Bugao Li, Guoliang Wang, Pengfei Gao   +8 more
doaj   +1 more source