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The human gut virome: composition, colonization, interactions, and impacts on human health
Frontiers in Microbiology, 2023 The gut virome is an incredibly complex part of the gut ecosystem. Gut viruses play a role in many disease states, but it is unknown to what extent the gut virome impacts everyday human health.
Evan Pargin +9 more
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Beyond the gut bacterial microbiota: The gut virome [PDF]
Journal of Medical Virology, 2016 The gastrointestinal tract is colonized with a highly different population of bacterial, viral, ad fungal species; viruses are reported to be dominant. The composition of gut virome is closely related to dietary habits and surrounding environment. Host and their intestinal microbes live in a dynamic equilibrium and viruses stimulate a low degree of ...
Columpsi, P +7 more
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Prophages are gut virome pioneers [PDF]
Nature Reviews Microbiology, 2020 A recent study shows that assembly of gut viral communities in early life occurs in distinct steps and is modulated by breastfeeding.
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Journal of Immunology Research, 2022 In recent years, there has been ample evidence illustrating the effect of microbiota on gut immunity, homeostasis, and disease. Most of these studies have engaged more efforts in understanding the role of the bacteriome in gut mucosal immunity and ...
Njinju Asaba Clinton +5 more
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The human gut virome: form and function [PDF]
Emerging Topics in Life Sciences, 2017 Advances in next-generation sequencing technologies and the application of metagenomic approaches have fuelled an exponential increase in our understanding of the human gut microbiome. These approaches are now also illuminating features of the diverse and abundant collection of viruses (termed the virome) subsisting with the microbial ecosystems ...
Ogilvie, Lesley, Jones, Brian
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Alterations in the Composition of Intestinal DNA Virome in Patients With COVID-19
Frontiers in Cellular and Infection Microbiology, 2021 Patients with Coronavirus Disease 2019 (COVID-19), due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection mainly present with respiratory issues and related symptoms, in addition to significantly affected digestive system ...
Zhen-Hua Lu +11 more
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Rapid evolution of the human gut virome [PDF]
Proceedings of the National Academy of Sciences, 2013 Humans are colonized by immense populations of viruses, which metagenomic analysis shows are mostly unique to each individual. To investigate the origin and evolution of the human gut virome, we analyzed the viral community of one adult individual over 2.5 y by extremely deep metagenomic sequencing (56 billion bases of purified ...
Samuel, Minot +5 more
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Altered human gut virome in patients undergoing antibiotics therapy for Helicobacter pylori
Nature Communications, 2023 Transient gut microbiota alterations have been reported after antibiotic therapy for Helicobacter pylori. However, alteration in the gut virome after H. pylori eradication remains uncertain. Here, we apply metagenomic sequencing to fecal samples of 44 H.
Lingling Wang +6 more
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Comparative analysis of gut DNA viromes in wild and captive Himalayan vultures
Frontiers in Microbiology, 2023 IntroductionHimalayan vultures (Gyps hinalayensis) are widely distributed on the Qinghai-Tibetan Plateau and play a crucial role in maintaining the ecological balance by feeding on decayed corpses of wild and domestic animals.
Jundie Zhai +20 more
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The human gut virome: a multifaceted majority [PDF]
Frontiers in Microbiology, 2015 Here, we outline our current understanding of the human gut virome, in particular the phage component of this ecosystem, highlighting progress, and challenges in viral discovery in this arena. We reveal how developments in high-throughput sequencing technologies and associated data analysis methodologies are helping to illuminate this abundant ...
Lesley Ann Ogilvie +3 more
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