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Does the Human Gut Virome Contribute to Host Health or Disease?

open access: yesViruses, 2023
The human gastrointestinal (GI) tract harbors eukaryotic and prokaryotic viruses and their genomes, metabolites, and proteins, collectively known as the “gut virome”.
Angela Quirino   +2 more
exaly   +4 more sources

Gut Inflammation and Immunity: What Is the Role of the Human Gut Virome? [PDF]

open access: yesMediators of Inflammation, 2015
The human virome comprises viruses that infect host cells, virus-derived elements in our chromosomes, and viruses that infect other organisms, including bacteriophages and plant viruses.
Alfredo Focà   +5 more
doaj   +5 more sources

Emerging roles of gut virome in pediatric diseases [PDF]

open access: yesInternational Journal of Molecular Sciences, 2021
In the last decade, the widespread application of shotgun metagenomics provided extensive characterization of the bacterial “dark matter” of the gut microbiome, propelling the development of dedicated, standardized bioinformatic pipelines and the ...
Salvatore Cucchiara   +4 more
core   +5 more sources

The human gut virome: composition, colonization, interactions, and impacts on human health [PDF]

open access: yesFrontiers in Microbiology, 2023
The gut virome is an incredibly complex part of the gut ecosystem. Gut viruses play a role in many disease states, but it is unknown to what extent the gut virome impacts everyday human health.
Evan Pargin   +9 more
doaj   +2 more sources

A metagenomic catalog of the early-life human gut virome [PDF]

open access: yesNature Communications
Early-life human gut microbiome is a pivotal driver of gut homeostasis and infant health. However, the viral component (known as “virome”) remains mostly unexplored.
Shuqin Zeng   +11 more
doaj   +10 more sources

The human gut virome: a multifaceted majority [PDF]

open access: yesFrontiers in Microbiology, 2015
Here we outline our current understanding of the human gut virome, in particular the phage component of this ecosystem, highlighting progress and challenges in viral discovery in this arena.
Lesley Ann Ogilvie   +6 more
core   +5 more sources

The human gut virome: form and function [PDF]

open access: yesEmerging Topics in Life Sciences, 2017
Advances in next generation sequencing technologies and the application of metagenomic approaches have fuelled an exponential increase in our understanding of the human gut microbiome.
Lesley A. Ogilvie   +3 more
core   +4 more sources

The human gut microbiota and virome: Potential therapeutic implications [PDF]

open access: yesDigestive and Liver Disease, 2015
Human gut microbiota is a complex ecosystem with several functions integrated in the host organism (metabolic, immune, nutrients absorption, etc.).
Scarpellini, Emidio   +2 more
core   +5 more sources

Viral metagenomics of the gut virome of diarrheal children with Rotavirus A infection

open access: yesGut Microbes, 2023
Diarrhea is a leading cause of morbidity and mortality in children worldwide and represents a major dysbiosis event. Rotavirus has been recognized as a global leading pathogen of diarrhea.
Siwen Bao   +16 more
doaj   +2 more sources

Gut virome-wide association analysis identifies cross-population viral signatures for inflammatory bowel disease

open access: yesMicrobiome
Background The gut virome has been implicated in inflammatory bowel disease (IBD), yet a full understanding of the gut virome in IBD patients, especially across diverse geographic populations, is lacking.
Xiangge Tian   +11 more
doaj   +2 more sources

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