Results 101 to 110 of about 8,960 (210)
Studying the gut virome in the metagenomic era: challenges and perspectives [PDF]
Abstract The human gut harbors a complex ecosystem of microorganisms, including bacteria and viruses. With the rise of next-generation sequencing technologies, we have seen a quantum leap in the study of human-gut-inhabiting bacteria, yet the viruses that infect these bacteria, known as bacteriophages, remain underexplored. In this review,
Garmaeva, Sanzhima +5 more
openaire +4 more sources
Virome Sequencing of the Human Intestinal Mucosal–Luminal Interface
While the human gut virome has been increasingly explored in recent years, nearly all studies have been limited to fecal sampling. The mucosal–luminal interface has been established as a viable sample type for profiling the microbial biogeography of the ...
Austin Yan +4 more
doaj +1 more source
Viruses as living processes [PDF]
John Dupre University of Exeter Egenis Byrne House, St German's Road Exeter EX4 4PJ UK Guttinger University of Exeter Egenis Byrne House, St German's Road Exeter EX4 4PJ United KingdomThe view that life is composed of distinct entities with well-defined ...
Dupré, John, Guttinger, S
core +1 more source
Mechanism of action of the intestinal microbiota on CNS autoimmune diseases. Environmental factors shape gut microbiota composition; dysbiosis alters microbial metabolites and antigenic signals. These modulate innate and adaptive immunity, affect barrier integrity, and influence CNS‐resident cells such as microglia and astrocytes, contributing to ...
Matteo Ceccon, Francesca Ronchi
wiley +1 more source
Clinical metagenomic next-generation sequencing (mNGS), the comprehensive analysis of microbial and host genetic material (DNA and RNA) in samples from patients, is rapidly moving from research to clinical laboratories. This emerging approach is changing
Chiu, Charles Y, Miller, Steven A
core
Microbial metabolites in tumor epigenetic regulation
The gut microbiome modulates tumor epigenetic regulation through bioactive metabolites derived from dietary substrates. Microbiota‐produced SCFAs, secondary BAs, one‐carbon metabolites, and tryptophan‐derived ligands regulate histone acetylation, DNA methylation, and chromatin remodeling via HDAC, DNMT, AhR, and metabolic cofactor‐dependent pathways ...
Wangzheqi Zhang +31 more
wiley +1 more source
Outlook Magazine, Winter 2018 [PDF]
https://digitalcommons.wustl.edu/outlook/1206/thumbnail ...
core +1 more source
We provide the first comprehensive analysis of changes in the gut bacteriome at different clinical stages of HTLV‐1 infection. HTLV‐1 infection is associated with a dysbiosis that includes reduced bacterial diversity and an inverted Firmicutes/Bacteroidetes ratio.
Lorena Abreu Fernandes +8 more
wiley +1 more source
ABSTRACT Tail fan necrosis (TFN) is a shell disease affecting spiny lobsters' outer integument, with significant implications for the health and commercial viability of red rock lobsters (Jasus edwardsii) in New Zealand. Despite its impact, the potential role of a microbial agent in TFN remains poorly understood.
Rebecca M. Grimwood +6 more
wiley +1 more source
Radiation‐induced intestinal injury is a common complication of abdominopelvic cancer radiotherapy, often associated with gut bacteriome dysbiosis. However, the involvement of gut virome in this process remains largely underexplored.
Xiaotong Zhao +17 more
doaj +1 more source

