Results 101 to 110 of about 8,960 (210)

Studying the gut virome in the metagenomic era: challenges and perspectives [PDF]

open access: yesBMC Biology, 2019
Abstract The human gut harbors a complex ecosystem of microorganisms, including bacteria and viruses. With the rise of next-generation sequencing technologies, we have seen a quantum leap in the study of human-gut-inhabiting bacteria, yet the viruses that infect these bacteria, known as bacteriophages, remain underexplored. In this review,
Garmaeva, Sanzhima   +5 more
openaire   +4 more sources

Virome Sequencing of the Human Intestinal Mucosal–Luminal Interface

open access: yesFrontiers in Cellular and Infection Microbiology, 2020
While the human gut virome has been increasingly explored in recent years, nearly all studies have been limited to fecal sampling. The mucosal–luminal interface has been established as a viable sample type for profiling the microbial biogeography of the ...
Austin Yan   +4 more
doaj   +1 more source

Viruses as living processes [PDF]

open access: yes, 2016
John Dupre University of Exeter Egenis Byrne House, St German's Road Exeter EX4 4PJ UK Guttinger University of Exeter Egenis Byrne House, St German's Road Exeter EX4 4PJ United KingdomThe view that life is composed of distinct entities with well-defined ...
Dupré, John, Guttinger, S
core   +1 more source

Microbial‐Immune Interplay in CNS Autoimmune Diseases: Lessons from Animal Models and Clinical Studies

open access: yesEuropean Journal of Immunology, Volume 56, Issue 2, February 2026.
Mechanism of action of the intestinal microbiota on CNS autoimmune diseases. Environmental factors shape gut microbiota composition; dysbiosis alters microbial metabolites and antigenic signals. These modulate innate and adaptive immunity, affect barrier integrity, and influence CNS‐resident cells such as microglia and astrocytes, contributing to ...
Matteo Ceccon, Francesca Ronchi
wiley   +1 more source

Clinical metagenomics. [PDF]

open access: yes, 2019
Clinical metagenomic next-generation sequencing (mNGS), the comprehensive analysis of microbial and host genetic material (DNA and RNA) in samples from patients, is rapidly moving from research to clinical laboratories. This emerging approach is changing
Chiu, Charles Y, Miller, Steven A
core  

Microbial metabolites in tumor epigenetic regulation

open access: yesiMeta, Volume 5, Issue 1, February 2026.
The gut microbiome modulates tumor epigenetic regulation through bioactive metabolites derived from dietary substrates. Microbiota‐produced SCFAs, secondary BAs, one‐carbon metabolites, and tryptophan‐derived ligands regulate histone acetylation, DNA methylation, and chromatin remodeling via HDAC, DNMT, AhR, and metabolic cofactor‐dependent pathways ...
Wangzheqi Zhang   +31 more
wiley   +1 more source

Outlook Magazine, Winter 2018 [PDF]

open access: yes, 2018
https://digitalcommons.wustl.edu/outlook/1206/thumbnail ...

core   +1 more source

Gut Microbiome Dysbiosis is Associated With Human T‐Lymphotropic Virus Type 1 (HTLV‐1) Infection and Disease Progression to HTLV‐1‐Associated Myelopathy/Tropical Spastic Paraparesis: A Cross‐Sectional Study

open access: yesSmart Medicine, Volume 5, Issue 1, February 2026.
We provide the first comprehensive analysis of changes in the gut bacteriome at different clinical stages of HTLV‐1 infection. HTLV‐1 infection is associated with a dysbiosis that includes reduced bacterial diversity and an inverted Firmicutes/Bacteroidetes ratio.
Lorena Abreu Fernandes   +8 more
wiley   +1 more source

A Novel Crustavirus as a Candidate Aetiology of Tail Fan Necrosis in New Zealand Red Rock Lobsters, Jasus edwardsii

open access: yesJournal of Fish Diseases, Volume 49, Issue 2, February 2026.
ABSTRACT Tail fan necrosis (TFN) is a shell disease affecting spiny lobsters' outer integument, with significant implications for the health and commercial viability of red rock lobsters (Jasus edwardsii) in New Zealand. Despite its impact, the potential role of a microbial agent in TFN remains poorly understood.
Rebecca M. Grimwood   +6 more
wiley   +1 more source

Commensal Viruses Promote Intestinal Stem Cell Regeneration Following Radiation Damage by Inhibiting Hyperactivation of RIG‐I and Notch Signals

open access: yesAdvanced Science
Radiation‐induced intestinal injury is a common complication of abdominopelvic cancer radiotherapy, often associated with gut bacteriome dysbiosis. However, the involvement of gut virome in this process remains largely underexplored.
Xiaotong Zhao   +17 more
doaj   +1 more source

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