Results 91 to 100 of about 38,819 (204)

Role of the tomato MARS1/ROUGH gene encoding a LYSINE‐SPECIFIC HISTONE DEMETHYLASE 1 in adventitious root and fruit skin formation

open access: yesJournal of Integrative Plant Biology, EarlyView.
The tomato mars1/rough mutant displays enhanced root regeneration and rough fruits due to ectopic cell proliferation. The causal gene encodes a lysine‐specific histone demethylase that normally maintains gene silencing. Its loss alters histone methylation, upregulating several genes, including those B‐type cyclins involved in tissue‐specific cellular ...
Eduardo Larriba   +14 more
wiley   +1 more source

EZH1 as a key mediator of exercise-induced H3K27me3 and H3K4me3 in mouse skeletal muscle

open access: yesAdvanced Exercise and Health Science
Epigenetic modification is a key mechanism that enhances the response of skeletal muscle to exercise training. Exercise-induced H3K27me3, which is co-modified with H3K4me3, is crucial for gene responses and adaptation in skeletal muscle; however, how ...
Junya Shimizu   +3 more
doaj   +1 more source

Recent advances in the genomics of sugarcane (Saccharum)

open access: yesJournal of Integrative Plant Biology, EarlyView.
This review systematically summarizes advances in sugarcane genomics, evolution, classification, and breeding practices. It identifies key research bottlenecks and proposes an integrated research framework to facilitate predictive sugarcane breeding, which provides valuable references for genetic improvement of other complex polyploid crops.
Tianyou Wang   +5 more
wiley   +1 more source

Chromatin Remodelling Complexes in Plant Adaptation to Abiotic Stress: Mechanisms and Perspectives

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT As sessile organisms, plants have evolved elaborate epigenetic regulatory networks to adapt to a wide range of abiotic stress. Chromatin remodelling is a core epigenetic regulatory mechanism that refers to the process by which chromatin remodelling complexes mediate dynamic changes in chromatin spatial conformation and DNA accessibility ...
Xiuxiu Zhang, Yueran Zhang, Jiang Li
wiley   +1 more source

Alternative silencing states of transposable elements in Arabidopsis associated with H3K27me3

open access: yesGenome Biology
Background The DNA/H3K9 methylation and Polycomb-group proteins (PcG)-H3K27me3 silencing pathways have long been considered mutually exclusive and specific to transposable elements (TEs) and genes, respectively in mammals, plants, and fungi.
Valentin Hure   +7 more
doaj   +1 more source

Born early, age fast: Consequences of premature birth on chronic disease and accelerated ageing

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend ELGANs are exposed to several postnatal pro‐oxidant stressors, including ambient and supplemental oxygen, mechanical ventilation, infections, hyperalimentation, excessive glucocorticoids and intermittent hypoxia. Since endogenous antioxidant defences are underdeveloped, this imbalance promotes oxidative stress and inflammation ...
Estelle B. Gauda   +5 more
wiley   +1 more source

Immune cells in the pathogenesis of abdominal aortic aneurysm: Roles, regulation and targeted interventions

open access: yesClinical and Translational Discovery, Volume 6, Issue 5, October 2026.
This review provides a comprehensive overview of how macrophages, neutrophils, T cells and other immune cells infiltrate the aortic wall, undergo phenotypic shifts and interact with one another in abdominal aortic aneurysm (AAA). Background Abdominal aortic aneurysm (AAA) is a lethal degenerative vascular disease with no approved clinical drugs. Immune
Junqi Peng   +3 more
wiley   +1 more source

Report on the 13th international workshop on the CCN family of genes and inaugural ARBIOCOM conference, Nice, France

open access: yesJournal of Cell Communication and Signaling, Volume 20, Issue 3, September 2026.
Celebration of the 13th ICCNS meeting joint to the 1st ARBIOCOM Conference held on the site of Nice in December 2025. Abstract The 13th International Workshop on the CCN Family of Genes, held in Nice as part of the inaugural ARBIOCOM World Conference, brought together investigators with diverse research backgrounds, disciplines, and expertise. Building
Bernard Perbal   +3 more
wiley   +1 more source

Mechanistic Insights Into the Association Between Gut Microbiota Diversity and Atherosclerosis, Acute Coronary Syndrome, and Peripheral Arterial Disease Progression

open access: yesClinical Cardiology, Volume 49, Issue 9, September 2026.
Proposed gut‐vascular framework linking microbial ecology to atherosclerotic disease. Diet and related exposures shape dysbiosis or microbial resilience; resulting changes in SCFAs, TMAO, bile acids, and LPS may modulate endothelial function, immune activation, and platelet activity, contributing to atherosclerosis, ACS, and PAD.
Amr Ali Mohamed Abdelgawwad El‐Sehrawy   +7 more
wiley   +1 more source

DNA Replication Stress‐Induced Transcriptome of Human Burkitt's Lymphoma Identifies Reciprocal Regulation Between MBD1 and BCL6 During Germinal Center‐Derived B‐Lymphomagenesis

open access: yesHematological Oncology, Volume 44, Issue 5, September 2026.
ABSTRACT BCL6 is a master transcriptional regulator of germinal center (GC) B cells. BCL6 is frequently translocated at the major translocation cluster (MTC) within intron 1 of the BCL6 locus, a hotspot commonly rearranged in diffuse large B cell lymphomas (DLBCLs).
Santosh Kumar Gothwal   +4 more
wiley   +1 more source

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