Results 101 to 110 of about 41,916 (253)

Forecasting Influenza Epidemics and Pandemics in the Age of AI and Machine Learning

open access: yesReviews in Medical Virology, Volume 36, Issue 1, January 2026.
ABSTRACT Influenza's rapid evolution, driven by its segmented RNA genome, high mutation rate, and extensive animal reservoirs, underpins its capacity to cause recurring epidemics and unpredictable pandemics. Recent advances in artificial intelligence (AI) and machine learning (ML) are transforming influenza forecasting by enabling the prediction of ...
Oleksandr Kamyshnyi   +5 more
wiley   +1 more source

Sequence Characterization of matrix protein (M1) in influenza A viruses (H1, H3 and H5)

open access: yesMicrobiology Research, 2011
This study brings the analysis of amino acid sequences of matrix protein (M1) from the influenza virus A (H1N1, H3N2 and H5N1) during 2007-2208. 741 sequences of M1 were compared, of them, H1N1 388; H3N2 251 and H5N1 102.
Jun Zhang   +4 more
doaj   +1 more source

Bridging Genomics and Clinical Medicine: RSVrecon Enhances RSV Surveillance With Automated Genotyping and Clinically Important Mutation Reporting

open access: yesInfluenza and Other Respiratory Viruses, Volume 20, Issue 1, January 2026.
ABSTRACT Background Respiratory Syncytial Virus (RSV) causes significant respiratory infections, particularly in young children and elderly adults. Genetic variations in the fusion (F) protein can reduce the efficacy of vaccination and monoclonal antibody treatments, emphasizing the need for genomic surveillance of this virus.
Lei Li   +6 more
wiley   +1 more source

Spread of Canine Influenza A(H3N2) Virus, United States [PDF]

open access: yesEmerging Infectious Diseases, 2017
A canine influenza A(H3N2) virus emerged in the United States in February-March 2015, causing respiratory disease in dogs. The virus had previously been circulating among dogs in Asia, where it originated through the transfer of an avian-origin influenza virus around 2005 and continues to circulate.
Ian E.H. Voorhees   +12 more
openaire   +3 more sources

The V223I substitution in hemagglutinin reduces the binding affinity to human-type receptors while enhancing the thermal stability of the H3N2 canine influenza virus

open access: yesFrontiers in Microbiology
Given the intimate relationship between humans and dogs, the H3N2 canine influenza viruses (CIVs) pose a threat to public health. In our study, we isolated four H3N2 CIVs from 3,758 dog nasal swabs in China between 2018 and 2020, followed by genetic and ...
Liling Liu   +11 more
doaj   +1 more source

Predicting Antigenic Variants of Influenza A/H3N2 Viruses

open access: yesEmerging Infectious Diseases, 2004
Current inactivated influenza vaccines provide protection when vaccine antigens and circulating viruses share a high degree of similarity in hemagglutinin protein. Five antigenic sites in the hemagglutinin protein have been proposed, and 131 amino acid positions have been identified in the five antigenic sites.
Min-Shi Lee, Jack Si-En Chen
openaire   +3 more sources

Insights into the antigenic advancement of influenza A(H3N2) viruses, 2011–2018

open access: yesScientific Reports, 2019
Influenza A(H3N2) viruses evade human immunity primarily by acquiring antigenic changes in the haemagglutinin (HA). HA receptor-binding features of contemporary A(H3N2) viruses hinder traditional antigenic characterization using haemagglutination ...
Patricia A Jorquera   +12 more
semanticscholar   +1 more source

Low influenza vaccine effectiveness against A(H3N2) associated hospitalizations in the 2016-2017 and 2017-2018 seasons of the Hospitalized Adult Influenza Vaccine Effectiveness Network (HAIVEN).

open access: yesJournal of Infectious Diseases, 2020
INTRODUCTION The 2016-2017 and 2017-2018 influenza seasons were notable for high number of hospitalizations for influenza A(H3N2) despite vaccine and circulating strain match.
E. Martin   +44 more
semanticscholar   +1 more source

Efficacy and Safety of Anti‐Influenza Drugs in 160 Chinese Children With Influenza A: A Retrospective Study

open access: yesJournal of Paediatrics and Child Health, Volume 62, Issue 1, Page 51-60, January 2026.
ABSTRACT Aim In this study, we aimed to provide a comprehensive analysis of real‐world implications for the therapeutic efficacy and safety of baloxavir marboxil, oseltamivir phosphate capsules and oseltamivir phosphate granules in the treatment of 160 Chinese children with influenza A. Methods This retrospective study included children aged 10–16 with
Wei Li   +8 more
wiley   +1 more source

How virus migration and meteorological elements shape the seasonality of influenza a/H3N2: A case study in China

open access: yesOne Health
Recent global influenza resurgences, escalating to pandemics, emphasize the urgency for effective vaccinations. Despite their efficacy, vaccines offer limited protection against A/H3N2 variants.
Yilan Liao   +12 more
doaj   +1 more source

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