Results 41 to 50 of about 704,117 (312)

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Olfactory receptor OR2AT4 regulates human hair growth

Nature Communications, 2018
Increasing evidence suggest that olfactory receptors can carry additional functions besides olfaction. Here, Chéret et al. show that stimulation of the olfactory receptor ORT2A4 by the odorant Sandalore® stimulates growth of human scalp hair follicles ex
Jérémy Chéret, Marta Bertolini, Leslie Ponce, Janin Lehmann, Teresa Tsai, Majid Alam, Hanns Hatt, Ralf Paus   +7 more
doaj   +1 more source

scRNA-Seq reveals distinct stem cell populations that drive hair cell regeneration after loss of Fgf and Notch signaling

eLife, 2019
Loss of sensory hair cells leads to deafness and balance deficiencies. In contrast to mammalian hair cells, zebrafish ear and lateral line hair cells regenerate from poorly characterized support cells.
Mark E. Lush, Daniel C Diaz, Nina Koenecke, Sungmin Baek, H. Boldt, Madeleine St. Peter, Tatiana Gaitán-Escudero, Andrés Romero-Carvajal, E. Busch-Nentwich, Anoja Perera, Kate E. Hall, Allison Peak, J. Haug, T. Piotrowski   +13 more
semanticscholar   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Development of a high-throughput UHPLC–MS/MS multi-method for the analysis of mycotoxins in plant-based milk alternatives as the basis for risk assessment

Frontiers in Nutrition
Plant-based alternatives to animal-based foods represent a rapidly growing market, as more and more consumers are willing to include these products into their daily diets. One particular segment is plant-based milk alternatives (PBMAs). Environmental and
Fabian Dick, Maximilian Schuster, Sarah Schneidemann-Bostelmann, Stefan Asam, Michael Rychlik   +4 more
doaj   +1 more source

Patient Counselling and Medicolegal Aspects of Hair Transplant Surgery

Indian Journal of Plastic Surgery, 2021
Hair transplantation being an elective aesthetic surgery, the importance of informed consent cannot be overstated. Explaining the condition of hair loss, the causes, progress, prognosis, and all available treatment options is a part of this process ...
Sandeep Suresh Sattur, Indu Sandeep Sattur   +1 more
doaj   +1 more source

Generation of inner ear organoids with functional hair cells from human pluripotent stem cells

Nature Biotechnology, 2017
The derivation of human inner ear tissue from pluripotent stem cells would enable in vitro screening of drug candidates for the treatment of hearing and balance dysfunction and may provide a source of cells for cell-based therapies of the inner ear. Here
Karl R. Koehler, J. Nie, Emma Longworth-Mills, Xiao-ping Liu, Jiyoon Lee, J. R. Holt, E. Hashino   +6 more
semanticscholar   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Treatment of wounds after operations on the anal canal and perineum

Амбулаторная хирургия
There are alimited number of publications in both domestic and foreign literature on the treatment of wounds in patients after anal canal and perineal surgery.
M. V. Abritsova, N. R. Torchua
doaj   +1 more source

FAM111B dysregulation promotes malignancy in fibrosarcoma and POIKTMP and a low-cost method for its mutation screening

Cancer Treatment and Research Communications, 2023
Introduction: Mutations in the uncharacterised human FAM111B gene are associated with POIKTMP, a rare multi-organ fibrosing disease. Recent studies also reported the overexpression of FAM111B in specific cancers.
Cenza Rhoda, Falone Sunda, Elvis Kidzeru, Nonhlanhla P. Khumalo, Afolake Arowolo   +4 more
doaj   +1 more source