Results 91 to 100 of about 5,738,873 (283)

The Effect of Environmental Contaminants on Hair Cell Regeneration in Larval Zebrafish [PDF]

open access: yes, 2013
Many contaminants, such as industrial pollutants, can be found in aquatic environments and may affect fish and other aquatic life. Some of these contaminants can also be found in trace amounts in water sources that are used for human consumption.
Young, Alex
core   +3 more sources

Functionalized Biomimetic Scaffolds for Human‐Derived Auditory Neural Circuit Construction

open access: yesAdvanced Science, EarlyView.
In Vitro Auditory Circuit Model. ABSTRACT Damage to auditory circuits results in sensorineural hearing loss. However, the scarcity of human inner ear tissue significantly hinders the development of therapies to preserve auditory function, creating a critical need for reliable in vitro models.
Pan Feng   +12 more
wiley   +1 more source

Platelet-derived growth factor signaling modulates adult hair follicle dermal stem cell maintenance and self-renewal

open access: yesnpj Regenerative Medicine, 2017
Hair loss: The protein that signals regeneration Signals from a protein that regulates cell division are essential to maintain the stem cells that regenerate hair follicles.
Raquel González   +7 more
doaj   +1 more source

Functional Sex Reversal in Adult Gonochoristic Teleosts is Mediated by Ovarian Germline Stem Cell Plasticity and Somatic Cell Transdifferentiation

open access: yesAdvanced Science, EarlyView.
Oocytes play crucial roles in maintaining ovarian fate in adult gonochoristic fish. Targeted oocyte ablation with aromatase inhibition triggers the activation of surviving germline stem cells and the transdifferentiation of somatic cells from granoulosa/theca to Sertoli/Leydig lineages, inducing a complete and functional female‐to‐male sex reversal ...
Yang Yang   +6 more
wiley   +1 more source

Re-expression of IGF-II is important for beta cell regeneration in adult mice [PDF]

open access: yes, 2012
Background The key factors which support re-expansion of beta cell numbers after injury are largely unknown. Insulin-like growth factor II (IGF-II) plays a critical role in supporting cell division and differentiation during ontogeny but its role in the
Nattkemper, Tim Wilhelm ; https://orcid.org/   +37 more
core   +2 more sources

Single‐Cell Profiling Reveals a Protective WNT5A‐ATF3‐FOSB Signaling Axis in Hair Follicle Stem Cells During Androgenetic Alopecia

open access: yesAdvanced Science, EarlyView.
Androgenetic alopecia (AGA) is a common form of hair loss with limited treatment options. Silencing of WNT5A signaling, which is widely known as the trigger of the ncWNT signaling pathway, happens in hair follicle stem cells from balding areas. It leads to downregulation of ATF3 and its target FOSB.
Ruiyu Luo   +10 more
wiley   +1 more source

Hair follicle germinative epidermal cells: a molecular study [PDF]

open access: yes, 1999
At the base of the hair follicle epidermal matrix is a population of germinative epidermal (GE) cells that is in close communication with the dermal papilla.
Whitehouse, C.J.   +1 more
core  

Neuromorphic Devices and Computing for Sensing, Memory, and Control

open access: yesAdvanced Science, EarlyView.
This review introduces neuromorphic devices made from diverse materials. These devices mimic neuronal functions and architectures and, when integrated with artificial or biological computing, can form closed loops with neurons for pressure, optical, acoustic, and biochemical sensing and modulation.
Zhengguang Zhu   +2 more
wiley   +1 more source

Dual‐Responsive Hydrogels Integrate Bioelectrical Stimulation and Piezo‐Photocatalysis for Regenerative Treatment of Infected Wounds

open access: yesAdvanced Science, EarlyView.
A wireless, dual‐responsive hydrogel (PVA/(PVDF‐TrFE)/BiOClBr@PDA) is developed to promote efficient regeneration of infected wounds by integrating piezoelectric stimulation with piezo‐photocatalytic pathways. Under simultaneous light and ultrasonic stimulation, the hydrogel generates therapeutic electrical cues and reactive oxygen species, disrupting ...
Baoying Dai   +15 more
wiley   +1 more source

Generation of sensory hair cells by genetic programming with a combination of transcription factors [PDF]

open access: yes, 2015
Mechanosensory hair cells (HCs) are the primary receptors of our senses of hearing and balance. Elucidation of the transcriptional networks regulating HC fate determination and differentiation is crucial not only to understand inner ear development but ...
Juniat, Stephanie   +11 more
core   +1 more source

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