Results 151 to 160 of about 15,676 (196)
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The efferents interconnecting auditory inner hair cells
Hearing Research, 1994The work describes the system of efferent terminals that interconnect inner hair cells through a chain of direct somatic synapses organized in repetitive patterns. The efferent boutons were discovered in the apical turns of 12-day-old (hearing) mice.
H M, Sobkowicz, S M, Slapnick
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Kainic acid selectively alters auditory dendrites connected with cochlear inner hair cells
Hearing Research, 1985Cochleas of adult guinea pigs and rats, and 6-day-old rat pups, were injected, through the round window, with 2 microliters of artificial classical Konishi perilymph containing 1 nmol kainic acid (KA). 5 min later, they were fixed, removed, and processed for electron microscopy. In all KA-treated cochleas, the injection resulted in a severe swelling of
R, Pujol +4 more
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A revised model of the inner-hair cell and auditory-nerve complex
The Journal of the Acoustical Society of America, 2002A revised computational model of the inner-hair cell (IHC) and auditory-nerve (AN) complex is presented and evaluated. Building on previous models, the algorithm is intended as a component for use in more comprehensive models of the auditory periphery. It combines smaller components that aim to be faithful to physiology in so far as is practicable and ...
Christian J, Sumner +3 more
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The Journal of the Acoustical Society of America, 2023
Sensorineural hearing loss (SNHL) effects on neural coding and perception have been largely associated with outer-hair-cell (OHC) dysfunction (e.g., reduced cochlear gain, reduced compression, broadened tuning). However, both inner-hair-cell (IHC) and OHC dysfunction occur in common hearing-loss etiologies, e.g., noise-induced and age-related ...
Madhurima Patra +3 more
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Sensorineural hearing loss (SNHL) effects on neural coding and perception have been largely associated with outer-hair-cell (OHC) dysfunction (e.g., reduced cochlear gain, reduced compression, broadened tuning). However, both inner-hair-cell (IHC) and OHC dysfunction occur in common hearing-loss etiologies, e.g., noise-induced and age-related ...
Madhurima Patra +3 more
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Simulation of the efficiency of inner hair cell secretion in the auditory pathway
2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2019Sound coding involves several stages of processing along the auditory path. Specifically, the Inner Hair Cells (IHC) act as sensory receptors and transduce acoustic information -frequency, intensity and duration of the stimulus- into neuronal signals. In this work, a stochastic model was implemented to achieve a better understanding of the IHC-auditory
J, Soto +3 more
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The masking level difference in chinchilla auditory cortex. Effects of inner hair cell loss
Hearing Research, 2003The purpose of the present study was to investigate responses from the unanesthetized chinchilla auditory cortex (AC) to conditions producing a masking level difference (MLD) in perceptual studies, both before and after inner hair cell (IHC) loss caused by carboplatin. Tungsten electrodes were chronically implanted in the right AC (active) and anterior
Yuqing, Guo, Robert, Burkard
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Two Modes of Auditory Hair Cell Loss following Acoustic Overstimulation in the Avian Inner Ear
ORL, 1997To determine the type of cell death occurring and how the removal of damaged cells proceeds following overstimulation, we examined chick basilar papillae using an in situ DNA nick end labeling method and transmission electron microscopy. Two distinct modes of hair cell loss were identified.
T, Nakagawa +5 more
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Phase opposition between inner and outer hair cells and auditory sound analysis
International Journal of Audiology, 1975Recordings of single-unit responses in the auditory nerve of normal and kanamycin-treated Mongolian gerbils indicate that inner and outer hair cells of the cochlea interact in phase opposition. After kanamycin treatment, the firing rate in some fibers is increased during the basilar membrane motion toward scala vestibuli, in others, during its motion ...
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Analysis of models for the synapse between the inner hair cell and the auditory nerve
The Journal of the Acoustical Society of America, 2005A general mathematical approach was proposed to study phenomenological models of the inner-hair-cell and auditory-nerve (AN) synapse complex. Two models (Meddis, J. Acoust. Soc. Am. 79(3), 702–711 (1986); Westerman and Smith, J. Acoust. Soc. Am. 83(6), 2266–2276 (1988)) were studied using this unified approach.
Xuedong, Zhang, Laurel H, Carney
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Loss of inner hair cell ribbon synapses and auditory nerve fiber regression in Cldn14 knockout mice
Hearing Research, 2020Proper functioning of the auditory nerve is of critical importance for auditory rehabilitation by cochlear implants. Here we used the Cldn14-/- mouse to study in detail the effects of Claudin 14 loss on auditory synapses and the auditory nerve. Mutations in the tight junction protein Claudin 14 cause autosomal recessive non-syndromic hearing loss ...
Maike, Claußen +2 more
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