Results 91 to 100 of about 89,289 (243)

RNA-seq transcriptomic analysis of adult zebrafish inner ear hair cells

open access: yesScientific Data, 2018
Although hair cells are the sensory receptors of the auditory and vestibular systems in the ears of all vertebrates, hair cell properties are different between non-mammalian vertebrates and mammals.
C. Barta   +7 more
semanticscholar   +1 more source

Rationally Designed TadA‐Derived Cytosine Editors Enable Context‐Independent Zebrafish Genome Editing

open access: yesAdvanced Science, EarlyView.
A next‐generation cytosine base editor (zTadCBE) and other variants are developed by combining the high‐efficiency (TadCBEa) and low‐indel (TadCBEMax) architectures, followed by the introduction of zebrafish‐optimized mutations (V82S, Q154R) in the TadA domain.
Wei Qin   +7 more
wiley   +1 more source

It takes two

open access: yeseLife, 2015
Two forms of an unconventional myosin motor protein have separate functions in the growth and maintenance of hair bundles in auditory hair cells.
Teresa Nicolson
doaj   +1 more source

Artificial Nervous Systems

open access: yesAdvanced Science, EarlyView.
By drawing inspiration from biological neural hierarchies and the working mechanisms of plasticity, researchers have constructed a series of bionic devices, including sensory devices, synapse devices, and artificial neural systems. They committed to simulating and surpassing the biological information processing function, thereby realizing the ...
Lu Yang   +5 more
wiley   +1 more source

Calcium action potentials in hair cells pattern auditory neuron activity before hearing onset

open access: yesNature Neuroscience, 2010
We found rat central auditory neurons to fire action potentials in a precise sequence of mini-bursts before the age of hearing onset. This stereotyped pattern was initiated by hair cells in the cochlea, which trigger brief bursts of action potentials in ...
Nicolas X. Tritsch   +7 more
semanticscholar   +1 more source

Fully Transparent Haptic Interface for High‐Resolution Tactile Feedback on Touchscreens

open access: yesAdvanced Science, EarlyView.
Integrating haptic feedback into touchscreens—enabling users to feel what they see on screen—has been a longstanding goal. In this article, B. Shan et al develop a transparent morphable haptic interface that transforms touchscreens into finely detailed, programmable morphable surfaces, enabling more effective and immersive human‐computer interaction ...
Boxue Shan   +13 more
wiley   +1 more source

Striatin Is Required for Hearing and Affects Inner Hair Cells and Ribbon Synapses

open access: yesFrontiers in Cell and Developmental Biology, 2020
Striatin, a subunit of the serine/threonine phosphatase PP2A, is a core member of the conserved striatin-interacting phosphatase and kinase (STRIPAK) complexes. The protein is expressed in the cell junctions between epithelial cells, which play a role in
Prathamesh T. Nadar-Ponniah   +14 more
doaj   +1 more source

Temporal–Spatial Replication of the Pulse Haptic Sensation Empowered by Multifunctional Piezoelectret

open access: yesAdvanced Intelligent Systems, EarlyView.
Dynamic pressure sensing, static pressure sensing, and haptic vibration are implemented on multifunctional piezoelectret devices with the universal structural design, further combined with the customized pressure device to comprehensively simulate and expand the Traditional Chinese Medicine (TCM) three‐finger palpation.
Liuyang Han   +9 more
wiley   +1 more source

Connexin-Mediated Signaling in Nonsensory Cells Is Crucial for the Development of Sensory Inner Hair Cells in the Mouse Cochlea

open access: yesJournal of Neuroscience, 2017
Mutations in the genes encoding for gap junction proteins connexin 26 (Cx26) and connexin 30 (Cx30) have been linked to syndromic and nonsyndromic hearing loss in mice and humans. The release of ATP from connexin hemichannels in cochlear nonsensory cells
Stuart L. Johnson   +8 more
semanticscholar   +1 more source

Speech Recognition with Cochlea‐Inspired In‐Sensor Computing

open access: yesAdvanced Intelligent Systems, EarlyView.
Traditional speech recognition methods rely on software‐based feature extraction that introduces latency and high energy costs, making them unsuitable for low‐power devices. A proof‐of‐concept demonstration is provided of a bioinspired tonotopic sensor for speech recognition that mimics the human cochlea, using a spiral‐shaped elastic metamaterial. The
Paolo H. Beoletto   +4 more
wiley   +1 more source

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