Results 131 to 140 of about 91,097 (243)

Disruption of the l‐DOPA Receptor Gpr143/OA1‐Gene in Mice Creates a Unique Mixed Psychosis‐Like Phenotype

Neuropsychopharmacology Reports, Volume 46, Issue 1, March 2026.
We analyzed the behavior of GPR143 gene‐deficient mice. GPR143‐KO mice displayed a mixed psychiatric phenotype. GPR143 may play a role in mesolimbic and mesocortical functions underlying sensory gating, reward, social hierarchy, cognition, and emotional regulation. ABSTRACT GPR143, originally identified as the gene product of ocular albinism 1 (OA1), a
Yoshio Goshima, Haruko Nakamura, Motokazu Koga, Junka Koyama, Yayoi Kimura, Maya N. Vasishth, Evan Y. Snyder, Masashi Asai, Kenta Sakai, Daiki Masukawa   +9 more
wiley   +1 more source

Inhibition of repulsive guidance molecule, RGMa, increases afferent synapse formation with auditory hair cells

Developmental Neurobiology, 2014
A. Brugeaud, M. Tong, Li-Da Luo, A. Edge
semanticscholar   +1 more source

A Novel Missense Variant in LMX1A Leads to Autosomal Dominant Nonsyndromic Hearing Loss

American Journal of Medical Genetics Part A, Volume 200, Issue 2, Page 531-534, February 2026.
ABSTRACT Hereditary nonsyndromic hearing loss (NSHL) is a prevalent entity associated with over 150 known causative genes, including LMX1A, which has fewer than 10 reported pathogenic variants. Here we present a novel missense variant in LMX1A in a family of European descent with hereditary hearing loss. Clinical and family histories were obtained, and
Ryan Chen, Dayna Morel Swols, Guney Bademci, Mustafa Tekin   +3 more
wiley   +1 more source

Electroreceptors with a different kind of buzz. [PDF]

J Physiol
The Journal of Physiology, Volume 604, Issue 1, Page 16-18, 1 January 2026.
Li GL, von Gersdorff H.
europepmc   +2 more sources

No News Is Good News Testing Modality and Redundancy in Immersive Augmented Reality

Journal of Computer Assisted Learning, Volume 42, Issue 1, February 2026.
ABSTRACT Background The modality and redundancy principles are well‐established within the cognitive theory of multimedia learning for their effectiveness in traditional media. However, previous studies applying these principles in virtual reality have shown contradictory results when immersive technologies are involved.
Vito Candido, Franz Lam, Dominik Petko, Alberto Cattaneo   +3 more
wiley   +1 more source

Auditory ganglion source of Sonic hedgehog regulates timing of cell cycle exit and differentiation of mammalian cochlear hair cells

Proceedings of the National Academy of Sciences of the United States of America, 2013
J. Bok, Colleen Zenczak, Chan Ho Hwang, Doris K. Wu   +3 more
semanticscholar   +1 more source

NMNAT1 Activates Autophagy to Delay D‐Galactose‐Induced Aging in Cochlear Hair Cells

Aging Cell, Volume 25, Issue 2, February 2026.
The study presents mechanistic insights into cochlear hair cells aging using cellular and explant models. The assessment into NMNAT1 regulated NAD+ metabolism, autophagy, and aging in ARHL. NMNAT1 overexpression restores autophagic activity and decelerates aging in cochlear hair cells.
Yongjie Wei, Wenqing Yang, Han Wu, Mengdie Kong, Dachuan Fan, Yuhua Zhang, Nan Cheng, Jiawei Du, Lingna Guo, Yuyang Li, Ye Zhang, Qian Dai, Wei Cao, Jianming Yang, Qiaojun Fang   +14 more
wiley   +1 more source

Presynaptic maturation in auditory hair cells requires a critical period of sensory-independent spiking activity

Proceedings of the National Academy of Sciences of the United States of America, 2013
Stuart L. Johnson, Stephanie Kuhn, Christoph Franz, N. Ingham, D. Furness, M. Knipper, K. Steel, J. Adelman, M. Holley, W. Marcotti   +9 more
semanticscholar   +1 more source

Simultaneous encoding of sensory features: the role of multiplexing and noise in tactile perception and neural representation

Biological Reviews, Volume 101, Issue 1, Page 539-553, February 2026.
ABSTRACT The nervous system's capacity to process complex stimuli has long intrigued neuroscientists, with multiplexing now recognized as a fundamental neural coding strategy. Multiplexing refers to the simultaneous encoding of multiple stimulus features via vi distinct components of neuronal responses, such as firing rates and precise temporal spike ...
Mohammad Amin Kamaleddin
wiley   +1 more source

Lis1 mediates planar polarity of auditory hair cells through regulation of microtubule organization

Development, 2013
C. Sipe, Lixia Liu, Jianyi Lee, Cynthia M. Grimsley-Myers, Xiaowei Lu   +4 more
semanticscholar   +1 more source