Results 131 to 140 of about 22,677 (167)
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Auditory amplification: outer hair cells pres the issue
Trends in Neurosciences, 2003Active feedback mechanisms in the ears of mammals amplify and tune the auditory response to sound stimuli, allowing these organisms to enjoy both exquisite sensitivity and sharp frequency selectivity. A requisite component of this feedback pathway has recently been identified.
Gwénaëlle S G, Géléoc +1 more
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Bifurcation and Chaos of Spontaneous Oscillations of Hair Bundles in Auditory Hair Cells
International Journal of Bifurcation and Chaos, 2021Various spontaneous oscillations and Hopf bifurcation have been observed in hair bundles of auditory hair cells, which play very important roles in the auditory function. In the present paper, the bifurcations and chaos of spontaneous oscillations of hair bundles are investigated in a theoretical model to explain the experimental observations. Firstly,
Ben Cao +3 more
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Two Components of Transducer Adaptation in Auditory Hair Cells
Journal of Neurophysiology, 1999Mechanoelectrical transducer currents in turtle auditory hair cells adapted to maintained stimuli via a Ca2+-dependent mechanism characterized by two time constants of ∼1 and 15 ms. The time course of adaptation slowed as the stimulus intensity was raised because of an increased prominence of the second component. The fast component of adaptation had a
Y C, Wu, A J, Ricci, R, Fettiplace
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Auditory Hair Cells and Sensory Transduction
2017The organs of the vertebrate inner ear respond to a variety of mechanical stimuli: semicircular canals are sensitive to angular velocity, the saccule and utricle respond to linear acceleration (including gravity), and the cochlea is sensitive to airborne vibration, or sound.
Jeffrey R. Holt +1 more
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Hair cell abnormality and auditory-nerve physiology
The Journal of the Acoustical Society of America, 1978Data are presented from 14 animals: 8 acoustically traumatized animals (with survival times greater than one year) and 6 unexposed animals (born and raised in a low-noise environment [Liberman, J. Acoust. Soc. Am. 61, S27(A) (1977)]). Electrophysiological data include threshold tuning curves and spontaneous discharge rates from several hundred single ...
M. C. Liberman, D. G. Beil
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Sorting of actin isoforms in chicken auditory hair cells
Journal of Cell Science, 1997Most nonmuscle cells of higher vertebrates contain two different actin isoforms, beta- and gamma-cytoplasmic actin. The beta-isoform is with few exceptions the predominant isoform in nonmuscle cells and tissues. Perturbation of the beta:gamma ratio has been shown to affect the organization of bundled actin filaments indicating that the beta- and gamma ...
D, Höfer, W, Ness, D, Drenckhahn
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Hepatocyte growth factor protects auditory hair cells from aminoglycosides
The Laryngoscope, 2009AbstractObjectives/Hypothesis:To examine the effect of hepatocyte growth factor (HGF) for protection of auditory hair cells against aminoglycosides and its molecular mechanisms.Study Design:Experimental study.Methods:We quantitatively assessed protective effects of HGF on mouse cochlear hair cells against neomycin toxicity using explant culture systems.
Yayoi S, Kikkawa +6 more
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Auditory hair cells in human fetuses: Synaptogenesis and ciliogenesis
Journal of Electron Microscopy Technique, 1990AbstractThis paper brings together the most recent findings concerning the development of human fetus cochlear hair cells, as observed using transmission and scanning electron microscopy (TEM and SEM). Specific attention is drawn to the formation of synapses and the growth of stereocilia.
M, Lavigne-Rebillard, R, Pujol
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The sensory and motor roles of auditory hair cells
Nature Reviews Neuroscience, 2006Cochlear hair cells respond with phenomenal speed and sensitivity to sound vibrations that cause submicron deflections of their hair bundle. Outer hair cells are not only detectors, but also generate force to augment auditory sensitivity and frequency selectivity.
Robert, Fettiplace, Carole M, Hackney
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Mechanical and electromotile characteristics of auditory outer hair cells
Medical & Biological Engineering & Computing, 1999The passive and active properties of the cochlear outer hair cell are studied. The outer hair cell is currently considered the major candidate for the active component of mammalian hearing. Understanding of its properties may explain the amplification and sharp frequency selectivity of the ear.
A A, Spector, W E, Brownell, A S, Popel
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