Advanced Science, Volume 13, Issue 26, 8 May 2026.ABSTRACT Extracellular vesicles (EVs) are nanoscale mediators of intercellular communication with diverse molecular cargoes that reflect their cell of origin. Advances in isolation, detection, and single‐particle analytics have revealed increasing molecular and functional heterogeneity, while exposing limitations in how EV identity and activity are ...
David J. Lundy +8 more
wiley +1 more source
Tuning and Amplification in Gecko Auditory Hair Cells
We developed an isolated auditory papilla of the crested gecko to record from the hair cells and explore the origins of frequency tuning. Low-frequency cells displayed electrical tuning, dependent on Ca2+-activated K+ channels; high-frequency cells, overlain with sallets, showed a variation in hair bundle stiffness which when combined with sallet mass ...
Fettiplace, Robert, Beurg, Maryline
openaire +3 more sources
Advanced Intelligent Systems, Volume 8, Issue 5, May 2026.ResearchConnect is an AI‐powered platform that automates researcher profiling, interdisciplinary team formation, and early‐stage research ideation. By extracting keywords from papers and web sources, it quickly clusters researchers into coherent teams and generates collaborative ideas using large language models. Validation on NSF‐funded projects shows
Akshay Vilas Jadhav +2 more
wiley +1 more source
Hair cell loss - cause or consequence of hearing loss? [PDF]
Front Cell Dev BiolCortada M, Levano S, Bodmer D.
europepmc +1 more source
Non‐verbal dichotic listening: A new cognitive hearing test for dementia
Alzheimer's &Dementia, Volume 22, Issue 5, May 2026.Abstract INTRODUCTION Central hearing difficulties are a feature of Alzheimer's disease (AD) but not well captured by standard speech perception tests. METHODS We developed a non‐verbal dichotic listening test (NVDLT) based on everyday sounds, and compared this with a standard verbal dichotic listening test (VDLT) in 36 people with primary progressive ...
Chris J. D. Hardy +12 more
wiley +1 more source
A Cross-Species Single-Cell Atlas Reveals Conserved Regulatory Networks and Candidate Hearing Loss Genes in the Cochlea. [PDF]
Genes (Basel)Cheng H, Ai F, Hua W, Bu F.
europepmc +1 more source
Metabotropic glutamate receptor 5 is associated with plasma GFAP dependent on age
Alzheimer's &Dementia, Volume 22, Issue 5, May 2026.Abstract INTRODUCTION We investigated the relationship between metabotropic glutamate receptor subtype 5 (mGluR5) availability and plasma biomarkers in individuals with cognitive impairment. METHODS Seventy‐one subjects were included (17 cognitively unimpaired [CU], 10 early‐onset cognitive impairment [EOCI], and 44 late‐onset cognitive impairment ...
Tangyue Hu +9 more
wiley +1 more source
ATG5-FOXA3 Axis Contributes to Lysosomal Biogenesis and Auditory Function in Kölliker's Organ. [PDF]
BiomedicinesChen P, Zhang J, Wang Y, Chen J.
europepmc +1 more source
Interval Timing Is Altered in Male Nrxn1+/− Mice: A Model of Autism Spectrum Disorder
Autism Research, Volume 19, Issue 5, May 2026.ABSTRACT Autism spectrum disorder (ASD) is characterized by impaired social interactions and communication, and increased repetitive and stereotypical behavior. Neuroimaging shows functional abnormalities in brain areas involved in temporal processing in autistic individuals, and they also show deficits in interval timing.
Kyle M. Roddick +3 more
wiley +1 more source
Correction: Kim et al. The Suppression of Ubiquitin C-Terminal Hydrolase L1 Promotes the Transdifferentiation of Auditory Supporting Cells into Hair Cells by Regulating the mTOR Pathway. <i>Cells</i> 2024, <i>13</i>, 737. [PDF]
CellsKim YJ +6 more
europepmc +1 more source