Results 241 to 250 of about 55,462 (279)
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Auditory illusions and the single hair cell
Nature, 1993Like our other senses, the auditory system can produce illusions. Prominent among these are distortion products: when listening to two tones, one of frequency f1 and the second of a higher frequency f2, an individual may hear not only these primary tones, but also a difference tone of frequency f2 - f1, a sum tone of frequency f2 + f1, and combination ...
F, Jaramillo, V S, Markin, A J, Hudspeth
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Neurofilament proteins in avian auditory hair cells
The Journal of Comparative Neurology, 1997The distribution of middle-weight neurofilament protein (NF-M), an intermediate filament of neurons, was examined in the developing and mature avian inner ear by using immunocytochemical techniques. NF-M was detected in auditory hair cells and VIIIth cranial nerve neurons.
E C, Oesterle, D I, Lurie, E W, Rubel
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Mechanosensitivity of mammalian auditory hair cells in vitro
Nature, 1986Intracellular responses recorded in vitro from the cochleas of anaesthetized mammals have shown that the mechanoreceptive inner and outer hair cells are sharply tuned, accounting for many of the properties of the afferent fibres in the auditory nerve. However, in vivo it has not been possible to measure directly the excitatory mechanical input to these
I J, Russell, G P, Richardson, A R, Cody
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Apical phosphatidylserine externalization in auditory hair cells
Molecular Membrane Biology, 2007In hair cells of the inner ear, phosphatidylserine (PS), detected with fluorescent annexin V labeling, was rapidly exposed on the external leaflet of apical plasma membranes upon dissection of the organ of Corti. PS externalization was unchanged by caspase inhibition, suggesting that externalization did not portend apoptosis or necrosis.
Xiaorui, Shi +2 more
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The sensory and motor roles of auditory hair cells
Nature Reviews Neuroscience, 2006Cochlear hair cells respond with phenomenal speed and sensitivity to sound vibrations that cause submicron deflections of their hair bundle. Outer hair cells are not only detectors, but also generate force to augment auditory sensitivity and frequency selectivity.
Robert, Fettiplace, Carole M, Hackney
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The efferents interconnecting auditory inner hair cells
Hearing Research, 1994The work describes the system of efferent terminals that interconnect inner hair cells through a chain of direct somatic synapses organized in repetitive patterns. The efferent boutons were discovered in the apical turns of 12-day-old (hearing) mice.
H M, Sobkowicz, S M, Slapnick
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Somatostatin and gentamicin‐induced auditory hair cell loss
The Laryngoscope, 2009AbstractObjective/Hypothesis:Hair cells of the mammalian auditory system do not regenerate, and therefore their loss leads to irreversible hearing loss. Aminoglycosides, among other substances, can irreversibly damage hair cells. Somatostatin, a peptide with hormone/neurotransmitter properties, has neuroprotective effects by binding to its receptor. In
Caelers, Antje +3 more
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Aligned Organization of Synapses and Mitochondria in Auditory Hair Cells
Neuroscience Bulletin, 2021Recent studies have revealed great functional and structural heterogeneity in the ribbon-type synapses at the basolateral pole of the isopotential inner hair cell (IHC). This feature is believed to be critical for audition over a wide dynamic range, but whether the spatial gradient of ribbon morphology is fine-tuned in each IHC and how the ...
Jing, Liu +8 more
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Sorting of actin isoforms in chicken auditory hair cells
Journal of Cell Science, 1997Most nonmuscle cells of higher vertebrates contain two different actin isoforms, beta- and gamma-cytoplasmic actin. The beta-isoform is with few exceptions the predominant isoform in nonmuscle cells and tissues. Perturbation of the beta:gamma ratio has been shown to affect the organization of bundled actin filaments indicating that the beta- and gamma ...
D, Höfer, W, Ness, D, Drenckhahn
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Two Components of Transducer Adaptation in Auditory Hair Cells
Journal of Neurophysiology, 1999Mechanoelectrical transducer currents in turtle auditory hair cells adapted to maintained stimuli via a Ca2+-dependent mechanism characterized by two time constants of ∼1 and 15 ms. The time course of adaptation slowed as the stimulus intensity was raised because of an increased prominence of the second component. The fast component of adaptation had a
Y C, Wu, A J, Ricci, R, Fettiplace
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