Electrophysiological properties of vestibular hair cells isolated from human crista. [PDF]
Mohamed N +7 more
europepmc +1 more source
Restoring Iron Homeostasis via Smoothened Inhibition: A Novel Strategy Against Hearing Loss
. ABSTRACT Sensorineural hearing loss (SNHL) induced by noise or aminoglycoside antibiotics is a significant public health concern without any FDA‐approved pharmaceutical therapies. Dysregulation of iron homeostasis and its subsequently induced ferroptosis has increasingly been identified as a key mechanism underlying cochlear hair cell (HC) damage ...
Huanyu Mao +9 more
wiley +1 more source
The Critical Thing about the Ear's Sensory Hair Cells. [PDF]
Hudspeth AJ, Martin P.
europepmc +1 more source
Transient-Evoked Otoacoustic Emissions May Reveal Damage to Outer Hair Cells Caused by Exposure to Recreational Noise: A Narrative Review. [PDF]
Zhou Z +6 more
europepmc +1 more source
AAVR Expression is Essential for AAV Vector Transduction in Sensory Hair Cells. [PDF]
Wu F +8 more
europepmc +1 more source
Single-molecule fluorescence microscopy reveals regulatory mechanisms of MYO7A-driven cargo transport in stereocilia of live inner ear hair cells. [PDF]
Miyoshi T +9 more
europepmc +1 more source
The role of cilia in the development, survival, and regeneration of hair cells. [PDF]
Boldizar H +6 more
europepmc +1 more source
Presynaptic Nrxn3 is essential for ribbon-synapse maturation in hair cells.
Jukic A +9 more
europepmc +1 more source
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Neurobiologists have been challenged by the desire to understand how the highly specialized ultrastructure of the sensory hair cells of the ear develops, how patterns of phenotypically distinct hair cells are formed and regenerate, and how their specific neural connections are formed.
J T, Corwin, M E, Warchol, M W, Kelley
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The increasing use of the hair follicle as a stem cell paradigm is due in part to the complex interplay between epithelial, dermal and other cell types, each with interesting differentiation potential and prospective therapeutic applications. This review focuses on research into the environmental niche, gene expression profiles and plasticity of hair ...
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