Results 71 to 80 of about 5,121,563 (149)

Lgr5 marks cycling, yet long-lived, hair follicle stem cells.

, 2008
In mouse hair follicles, a group of quiescent cells in the bulge is believed to have stem cell activity. Lgr5, a marker of intestinal stem cells, is expressed in actively cycling cells in the bulge and secondary germ of telogen hair follicles and in the ...
Clevers, H., Kasper, M., van Es, J.H., Snippert, H.J.G., Jaks, V., Toftgard, R., Barker, N.   +6 more
core   +1 more source

Stem cells cycle in the hair follicle [PDF]

Nature Reports Stem Cells, 2008
An intestinal marker of cycling cells, Lgr5, helps identify surprising activity in the hair follicle ...
openaire   +1 more source

Regenerative potential of CD200- subpopulations of hair follicle bulge

Frontiers in Cell and Developmental Biology
The hair follicle bulge is regarded as a reservoir of epithelial stem cells for hair regeneration. Hair follicle bulge cells are generally characterized by CD200 expression.
Ting Sun, Ting Sun, Sayuri Hamano, Jing Chen, Lichen Ling, Jinran Lin, Lei Yan, Lei Yan, Tatsuto Kageyama, Tatsuto Kageyama, Fuyue Wu, Zheng Lin Tan, Wenyu Wu, Junji Fukuda, Junji Fukuda   +14 more
doaj   +1 more source

Augmenting Peripheral Nerve Regeneration Using Hair Follicle Stem Cells in Rats

Basic and Clinical Neuroscience, 2022
Introduction: Cell therapy is the most advanced treatment of peripheral nerve injury. This study aimed to determine the effects of transplantation of hair follicle stem cells on the regeneration of the sciatic nerve injury in rats.
Leila Beigom Hejazian, Zeinab Akbarnejad, Fatemeh Moghani Ghoroghi, Banafshe Esmaeilzade, Samira Chaibakhsh   +4 more
doaj  

Effects of UV Induced-Photoaging on the Hair Follicle Cycle of C57BL6/J Mice

Clinical, Cosmetic and Investigational Dermatology, 2021
Xu Zhai,1 Meihua Gong,1,2 Yixuan Peng,1 Daping Yang1 1Department of Plastic Surgery, The 2nd Hospital of Harbin Medical University, Harbin, People’s Republic of China; 2Department of Plastic and Cosmetic Surgery, Shenzhen People’s Hospital ...
Zhai X, Gong M, Peng Y, Yang D
doaj  

The effects of overexpression of lamin a and two mutants associated with premature aging on stem cell differentiation and proliferation. [PDF]

, 2007
The nuclear lamina is composed of A and B-type lamins and performs a number of functions within the nucleus. Mutations within lamins give rise to a group of diseases called laminopathies including autosomal dominant Emery-Dreifuss muscular dystrophy and ...
Gibbs-Seymour, Ian
core  

Disrupted cholesterol biosynthesis and hair follicle stem cell impairment in the onset of alopecia.

PLoS ONE
BackgroundHair follicle cycle and the functioning of stem cells in alopecia are influenced by the suppression of cholesterol synthesis and the accumulation of sterol intermediates.ObjectiveThis investigation aims to elucidate the regulatory function of ...
Leemon Nikhila, Suresh Surya, Shahul Hameed Najeeb, Thankachan Mangalathettu Binumon, Aayush Gupta, Sandeep Gopalakrishnan, Mahsa Dabagh, Parameswara Panicker Sreejith   +7 more
doaj   +1 more source

Therapeutic Potential of Patient iPSC-Derived iMelanocytes in Autologous Transplantation

Cell Reports, 2019
Summary: Induced pluripotent stem cells (iPSCs) are a promising melanocyte source as they propagate indefinitely and can be established from patients. However, the in vivo functions of human iPSC-derived melanocytes (hiMels) remain unknown.
Li-Ping Liu, Yu-Mei Li, Ning-Ning Guo, Shu Li, Xiaolong Ma, Yi-Xuan Zhang, Yimeng Gao, Jian-Ling Huang, Dong-Xu Zheng, Lu-Yuan Wang, Hui Xu, Lijian Hui, Yun-Wen Zheng   +12 more
doaj   +1 more source

Use of in vitro human keratinocyte models to study the effect of cooling on chemotherapy drug-induced cytotoxicity [PDF]

, 2014
A highly distressing side-effect of cancer chemotherapy is chemotherapy-induced alopecia (CIA). Scalp cooling remains the only treatment for CIA, yet there is no experimental evidence to support the cytoprotective capacity of cooling. We have established
van den Hurk, Corina J., Komen, Manon M., Hussain, Omar, Dunnill, Christopher, Georgopoulos, Nikolaos T., Al-Tameemi, Wafaa, Collett, Andrew   +6 more
core   +1 more source

Hair Follicle Dermal Cells Support Expansion of Murine and Human Embryonic and Induced Pluripotent Stem Cells and Promote Haematopoiesis in Mouse Cultures

Stem Cells International, 2018
In the hair follicle, the dermal papilla (DP) and dermal sheath (DS) support and maintain proliferation and differentiation of the epithelial stem cells that produce the hair fibre.
Jun Liu, Claire A. Higgins, Jenna C. Whitehouse, Susan J. Harris, Heather Crawford, Angela M. Christiano, Majlinda Lako, Nicholas Hole, Colin A. B. Jahoda   +8 more
doaj   +1 more source