Results 81 to 90 of about 5,121,563 (149)

Have Hair Follicle Stem Cells Shed Their Tranquil Image? [PDF]

, 2008
In a recent issue of Nature Genetics, Jaks et al. (2008) demonstrate that hair follicle cells expressing the intestinal stem cell marker Lgr5 are hair follicle epithelial stem cells.
Andersen, Bogi, Lin, Kevin K.
core   +1 more source

Melatonin-Mediated Circadian Rhythm Signaling Exhibits Bidirectional Regulatory Effects on the State of Hair Follicle Stem Cells

Biomolecules
The development and regulation of hair are widely influenced by biological rhythm signals. Melatonin plays a crucial role as a messenger in transmitting biological rhythm signals, and its impact on hair development has been well documented.
Yu Zhang, Xuefei Zhao, Shuqi Li, Yanchun Xu, Suying Bai, Wei Zhang   +5 more
doaj   +1 more source

Inhibition of the Hippo pathway by verteporfin reduces the proliferation and stemness of rat hair follicle neural crest stem cells under hypoxia

FASEB BioAdvances
Hair follicle neural crest stem cells reside in the bulge region of the outer root sheath of hair follicles, originate from the ectoderm, and have multidirectional differentiation potential, making them ideal candidates for tissue engineering ...
Weihai Liu, Suhua Chen, Xin Chen, Lixiang Xue, Yan Wang, Jun Yang   +5 more
doaj   +1 more source

Stem cell-based approaches for alopecia: A narrative review of current and emerging treatment strategies

Cell Transplantation
The natural cycle of hair growth and shedding is continuous. However, an abnormal rate of hair regrowth can signal alopecia, a condition characterized by excessive hair loss and thinning.
Pitsunan Paphawannasri, Tulyapruek Tawonsawatruk, Jitrada Phetfong, Aungkura Supokawej   +3 more
doaj   +1 more source

Differences in Growth Response of Human Hair Follicle Mesenchymal Stem Cells to Herbal Extracts and a Growth Factor

Journal of Medicinal Plants, 2018
Background: One of the key questions in biochemistry is why cell becomes aged and what are the involved factors? Why cell growth is stopped after some divisions and cells become senescent?
HR Ahmadi Ashtiani, F Salehinia, H Rastegar, AA Allameh, Sh Rezazadeh   +4 more
doaj  

Dermal T cell immunity and key regulatory signaling pathways: Implications in immune-mediated alopecia and hair regeneration

Genes and Diseases
Mammalian hair follicles undergo periodic regeneration, with recent research highlighting the immunological niche as a critical regulator of stem cell activity and hair follicle regeneration.
Nana Tao, Qingru Sun, Yuyuan Ying, Yitao Wang, Jianli Gao   +4 more
doaj   +1 more source

Lgr6 marks stem cells in the hair follicle that generate all cell lineages of the skin

, 2010
Mammalian epidermis consists of three self-renewing compartments: the hair follicle, the sebaceous gland, and the interfollicular epidermis. We generated knock-in alleles of murine Lgr6, a close relative of the Lgr5 stem cell gene.
Vries, R.G.J., van de Wetering, M.L., Clevers, H., Stange, D.E., Toftgard, R., Barker, N., van den Born, M.M.W., Kasper, M., Snippert, H.J.G., van Es, J.H., Jaks, V., Haegebarth, A., Begthel, H.L.   +12 more
core   +1 more source

Neural Stem Cells Restore Hair Growth through Activation of the Hair Follicle Niche

Cell Transplantation, 2016
Several types of hair loss result from the inability of hair follicles to initiate the anagen phase of the hair regeneration cycle. Modulating signaling pathways in the hair follicle niche can stimulate entry into the anagen phase.
Insik Hwang, Kyung-Ah Choi, Hang-Soo Park, Hyesun Jeong, Jeong-Ok Kim, Ki-Cheon Seol, Han-Jin Kwon, In-Hyun Park, Sunghoi Hong Ph.D.   +8 more
doaj   +1 more source

Caracterização de populações de células-tronco obtidas de folículos pilosos de camundongos e avaliação do seu potencial para diferenciação em fenótipos epidermais [PDF]

, 2011
TCC(graduação) - Universidade Federal de Santa Catarina. Centro de Ciências Biológicas. Biologia.O folículo piloso é um anexo epidérmico, cujo desenvolvimento tem início no período embrionário.
Marcon, Bruna Hilzendeger
core  

Dissecting the boundary of quiescence and activation of murine melanocyte stem cells in the hair follicle niche

npj Regenerative Medicine
Melanocyte stem cells (McSCs) are a crucial melanocyte reservoir within the hair follicle niche. This review provides an overview of the processes for McSC quiescence and activation.
Tatsuya Ogawa, Min Chen, Soung-Hoon Lee, Denise L. Gay, Mayumi Ito   +4 more
doaj   +1 more source