Results 51 to 60 of about 31,793 (202)

Intravenous Haloperidol versus Midazolam in Management of Conversion Disorder; a Randomized Clinical Trial

Emergency, 2018
Introduction: Conversion disorder is a condition in which the patient shows psychological stress in physical ways. This study aimed to compare the effects of haloperidol versus midazolam in patients with conversion disorder.
Mohammadali Jafari, Amir Aliheidari Biuki, Majid Hajimaghsoudi, Mehdi Bagherabadi, Ehsan Zarepur   +4 more
doaj   +3 more sources

What happens after an oral ingestion of haloperidol decanoate? – A case report

Jornal Brasileiro de Psiquiatria, 2019
Haloperidol decanoate is a first generation antipsychotic drug used to treat patients with schizophrenic disorder who require prolonged parenteral antipsychotic therapy.
João Perestrelo, Ana Coutinho, Georgina Lapa   +2 more
doaj   +1 more source

Epileptic–Dyskinetic Encephalopathy Associated with a PPP3CA Variant: Expansion of the Phenotypic Spectrum

Movement Disorders Clinical Practice, EarlyView.
Bruno Antunes Contrucci, Ursula Thomé, Larissa Aparecida Batista, Ana Laura Volpi Martins Lorenzoni, Carla Andrea Cardoso Tanuri Caldas, Americo Ceiki Sakamoto, Israel Gomy, Lisandra Mesquita Batista, Marcela Lopes de Almeida, Ana Paula Andrade Hamad, Guillermo Andrey Ariza Traslaviña   +10 more
wiley   +1 more source

An Electronic Health Record “Nudge” to Reduce Antipsychotic Medication Prescribing for Primary Care Patients With Dementia: A Pragmatic RCT

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background We hypothesized that an electronic health record (EHR) alert grounded in behavioral science could reduce new antipsychotic medication prescriptions for older adults with dementia. Methods We conducted a pragmatic clinical trial at a large academic health system, randomizing providers to receive the alert (intervention) or not ...
Catherine A. Sarkisian, Chad Wes Villaflores, Anne M. Walling, Sitaram S. Vangala, Eric M. Cheng, Suzanne Bliven Shu, Ajaya Pillai, Grace Y. Cheng, Noah Goldstein, John Mafi   +9 more
wiley   +1 more source

Antipsychotics‐Induced Hyposalivation Mediated by Impaired Salivary Ca2+ Signaling

Oral Diseases, EarlyView.
ABSTRACT Objectives Antipsychotic‐induced salivary dysfunction such as hyposalivation is a prevalent clinical challenge that severely compromises oral health and quality of life. Although typical and atypical antipsychotics have their therapeutic target in the central nervous system, their direct molecular mechanisms within the salivary glands remain ...
Chaelin Chung, Soohyun Kim, Yoo‐Bin Kim, Hee‐Kyung Park, Se‐Young Choi   +4 more
wiley   +1 more source

Effect of single doses of droperidol or haloperidol on QTc Interval

INNOVATIONS in Pharmacy
Purpose: Droperidol and haloperidol are nonselective dopamine receptor blockers with clinical indications including postoperative nausea and vomiting and agitation.
Emily Stephens, Rachel Kahle, Lindsey Ferraro, Laura Schulz   +3 more
doaj   +1 more source

Beat‐to‐beat variability of ventricular repolarization reveals sex‐specific instability and proarrhythmic risk

The Journal of Physiology, EarlyView.
Abstract figure legend A mechanistic framework linking sex‐dependent dynamical instability to proarrhythmic risk. Sex‐specific human ventricular models show that upstream modulators, including biological sex, hormones, drugs and heart disease, promote steeper APD restitution in female than male and enhance dynamical instability.
Daisuke Sato, Lorenzo Santini, Raffaele Coppini, Eleonora Grandi   +3 more
wiley   +1 more source

THE HISTOPATHOLOGIC EFFECT OF SHORT-TERM ADMINISTRATION OF HALOPERIDOL ON RABBIT STRIATUM

Psychiatry and Clinical Psychopharmacology, 2021
Objective: Studies related to mechanism of action of antipsychotic drugs are being gone on and still some studies are carried out whether these drugs might lead to structural changes in brain and whether these changes might be associated with ...
Nazan Aydın, Mehmet Dumlu Aydın, Ali Çayköylü, Cemal Gündoğdu, Fazlı Erdoğan   +4 more
doaj  

Analisis Efektivitas Terapi dan Biaya antara Haloperidol Kombinasi dengan Risperidon Kombinasi pada Terapi Skizofrenia Fase Akut

Mutiara Medika, 2015
Skizofrenia merupakan gangguan jiwa berat dengan perjalanan penyakit terdiri dari fase akut, fase stabilisasi dan fase stabil. Pemilihan terapi yang tepat pada fase akut akan mempengaruhi prognosis pasien.
Imaniar Ranti, Andi Fauziyar Octaviany, Sekar Kinanti   +2 more
doaj   +1 more source

Mechanism‐Informed Pharmacotherapy Optimization and Deprescribing: A Redox–Mitochondrial Framework

Pharmacology Research &Perspectives, Volume 14, Issue 5, October 2026.
From cumulative drug burden to mitochondrial stress and functional decline. The graphical abstract summarizes the central concept of the review, illustrating how cumulative pharmacotherapy exposure may contribute to redox–mitochondrial stress and thereby reduce biological and functional resilience.
Boštjan Martinc
wiley   +1 more source