Results 81 to 90 of about 68,822 (222)

Recent Saccadic Eye Movement Research Uncovers Patterns of Cognitive Dysfunction in Schizophrenia. [PDF]

open access: yes, 2001
The frontal cortex and the subcortical areas of the brain play a major role in the control of thought and action. Eye movements are increasingly used in neuropsychological research to explore the executive and sensorimotor functions of such neural ...
Broerse, Annelies, Crawford, Trevor J.
core  

Psychiatric manifestations of multiple sclerosis and acute disseminated encephalomyelitis [PDF]

open access: yes, 2006
It is unusual for acute disseminated encephalomyelitis and multiple sclerosis to present as purely psychiatric disorders. We report five patients with such demyelinating diseases and symptoms of psychosis, depression or anxiety.
Brinar, Marko   +3 more
core   +1 more source

Vesicular glutamate transporter VGLUT2 expression emerges in substantia nigra dopamine neurons in mouse models of parkinsonism in the absence of neurodegeneration

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Subsets of midbrain dopamine (DA) neurons express the vesicular glutamate transporter VGLUT2 and can release the excitatory neurotransmitter glutamate. VGLUT2+ DA neurons of the substantia nigra pars compacta (SNc) were shown to be more resistant to neurodegeneration in animal models of Parkinson's disease (PD ...
Sivakumar Srinivasan   +2 more
wiley   +1 more source

Rapid tranquilization in a psychiatric emergency room: A naturalistic cohort study in 12 h

open access: yesPsychiatry Research Communications
The purpose of this study was to conduct a naturalistic assessment of the efficacy of four distinct fast tranquilization techniques (intramuscular haloperidol, midazolam, haloperidol plus promethazine, or haloperidol plus midazolam) over a period of 12 h.
Leonardo Baldaçara   +4 more
doaj   +1 more source

Annual Research Review: Psychosis in children and adolescents: key updates from the past 2 decades on psychotic disorders, psychotic experiences, and psychosis risk

open access: yesJournal of Child Psychology and Psychiatry, Volume 66, Issue 4, Page 460-476, April 2025.
Psychosis in children and adolescents has been studied on a spectrum from (common) psychotic experiences to (rare) early‐onset schizophrenia spectrum disorders. This research review looks at the state‐of‐the‐art for research across the psychosis spectrum, from evidence on psychotic experiences in community and clinical samples of children and ...
Ian Kelleher
wiley   +1 more source

Analisis Efektivitas Terapi dan Biaya antara Haloperidol Kombinasi dengan Risperidon Kombinasi pada Terapi Skizofrenia Fase Akut

open access: yesMutiara Medika, 2015
Skizofrenia merupakan gangguan jiwa berat dengan perjalanan penyakit terdiri dari fase akut, fase stabilisasi dan fase stabil. Pemilihan terapi yang tepat pada fase akut akan mempengaruhi prognosis pasien.
Imaniar Ranti   +2 more
doaj   +1 more source

5-HT2A Receptors Modulate Dopamine D2-mediated Maternal Effects [PDF]

open access: yes, 2020
Serotonin 5-HT2A receptors are expressed throughout the mesolimbic and mesocortical dopamine pathways, and manipulation of this receptor system has a profound impact on dopamine functions and dopamine-mediated behaviors.
Gao, Jun
core   +1 more source

Time perception and its neuropsychological correlates in patients with schizophrenia and in healthy volunteers [PDF]

open access: yes, 2009
Disordered time perception has been reported in schizophrenia. We investigated time perception dysfunction and its neuropsychological correlates in patients with schizophrenia.
Andreasen   +56 more
core   +1 more source

Electromechanical modelling and simulation of human‐induced pluripotent stem cell‐derived cardiomyocytes predict drug‐induced contractility effects

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend A study described in this paper describes a new tool for hiPSC‐CM electromechanical behaviour simulations using mathematical modelling. The model enables in silico assays making drug testing quick, comprehensive and accurate. New hiPSC‐CM models can be used as a platform to integrate in vitro and in silico findings.
Milda Folkmanaite   +9 more
wiley   +1 more source

THE HISTOPATHOLOGIC EFFECT OF SHORT-TERM ADMINISTRATION OF HALOPERIDOL ON RABBIT STRIATUM

open access: yesPsychiatry and Clinical Psychopharmacology, 2021
Objective: Studies related to mechanism of action of antipsychotic drugs are being gone on and still some studies are carried out whether these drugs might lead to structural changes in brain and whether these changes might be associated with ...
Nazan Aydın   +4 more
doaj  

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