Results 201 to 210 of about 37,629 (254)

Resolving three GABA induced electrogenic events and GABA‐coupling stoichiometry for Na+ and Cl− in hGAT‐1

open access: yesThe FEBS Journal, EarlyView.
Using solid‐supported membrane electrophysiology, we resolved three electrogenic events during GABA transport by the human GAT‐1 transporter. A rapid occlusion step (E1) is followed by a GABA‐induced Na+ leak current (E2), which becomes prominent under steep Na+ gradients, and a slower current associated with Na+‐coupled GABA transport (E3 ...
Rocco Zerlotti   +8 more
wiley   +1 more source

Framework for headache management in pediatric patients with stroke and cerebrovascular lesions: A narrative review

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective To present a practical, evidence‐based framework for the management of headache disorders in pediatric patients with prior stroke or underlying cerebral vascular lesions, with particular attention to safety and efficacy of pharmacologic and non‐pharmacologic therapies.
Allison C. Hyland   +7 more
wiley   +1 more source

Functional and Histological Analysis of Stem Cell and Amniotic Membrane Implantation After Acute Myocardial Infarction with Left Ventricular Dysfunction: Experimental Study. [PDF]

open access: yesInt J Mol Sci
Rossa ICM   +12 more
europepmc   +1 more source

Life‐stage variation in Sable Shearwater (Ardenna carneipes) physiology assessed using proteomics

open access: yesIbis, EarlyView.
Life‐stage transitions in seabirds involve substantial shifts in physiological demands, yet the molecular mechanisms underpinning these changes remain poorly resolved. Here we applied untargeted data‐independent acquisition mass spectrometry (DIA‐MS) to characterize and compare the plasma proteomes of fledgling and adult Sable Shearwaters Ardenna ...
Alix M. de Jersey   +5 more
wiley   +1 more source

Systemic Lipidomics Identifies Altered Ceramide–Phospholipid Balance Associated With Periodontitis Severity: A Cross‐Sectional Study With 12‐Year Follow‐Up

open access: yesJournal of Clinical Periodontology, EarlyView.
ABSTRACT Aim To investigate whether periodontitis stage and grade are associated with circulating active lipid mediators and whether baseline lipid species predict periodontitis progression. Materials and Methods The study included 473 Finnish participants from the Parogene cohort undergoing coronary angiography, with 12‐year follow‐up data available ...
Minja Tuomivaara   +11 more
wiley   +1 more source

Liraglutide combined with dapagliflozin treatment improves myocardial disease and endothelial dysfunction in T2DM mice

open access: yesJournal of Diabetes Investigation, EarlyView.
Liraglutide combined with Dapagliflozin treatment improves myocardial disease and endothelial dysfunction in T2DM mice. Diabetic cardiomyopathy (DCM) and endothelial dysfunction were established in mice via HFD and STZ injection. The combination therapy of Liraglutide and Dapagliflozin synergistically improved metabolic parameters and attenuated ...
An‐Jun Tan   +5 more
wiley   +1 more source

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