Concordance of copy number abnormality detection using SNP arrays and Multiplex Ligation-dependent Probe Amplification (MLPA) in acute lymphoblastic leukaemia [PDF]
, 2020 In acute lymphoblastic leukaemia, MLPA has been used in research studies to identify clinically relevant copy number abnormality (CNA) profiles. However, in diagnostic settings other techniques are often employed.
Bashton, Matthew +7 more
core +1 more source
The evolution of hermaphroditism by an infectious male-derived cell lineage : an inclusive-fitness analysis [PDF]
, 2014 This work was supported by funding from Balliol College, the Royal Society (A.G.), and the University of Groningen (L.R.).There has been much recent interest in the role for genetic conflicts to drive the evolution of genetic systems.
Gardner, Andy, Ross, Laura
core +1 more source
Haploidy in Tobacco Induced by PsASGR-BBML Transgenes via Parthenogenesis
Genes, 2020 Background: Engineering apomixis in sexually reproducing plants has been long desired because of the potential to fix hybrid vigor. Validating the functionality of genes originated from apomictic species that contribute to apomixis upon transfer to ...
Zhifen Zhang +3 more
semanticscholar +1 more source
Generation of Mouse Haploid Somatic Cells by Small Molecules for Genome-wide Genetic Screening
Cell Reports, 2017 The recent success of derivation of mammalian haploid embryonic stem cells (haESCs) has provided a powerful tool for large-scale functional analysis of the mammalian genome.
Zheng-Quan He +16 more
doaj +1 more source
Ancient evolutionary trade-offs between yeast ploidy states. [PDF]
PLoS Genetics, 2013 The number of chromosome sets contained within the nucleus of eukaryotic organisms is a fundamental yet evolutionarily poorly characterized genetic variable of life.
Enikö Zörgö +8 more
doaj +1 more source
eLife, 2022 Complex mechanisms regulate gene dosage throughout eukaryotic life cycles. Mechanisms controlling gene dosage have been extensively studied in animals, however it is unknown how generalizable these mechanisms are to diverse eukaryotes.
Sean Akira Montgomery +7 more
doaj +1 more source
Evolution Letters, 2019 Haplodiploidy has evolved repeatedly among invertebrates, and appears to be associated with inbreeding. Evolutionary biologists have long debated the possible benefits for females in diplodiploid species to produce haploid sons–beginning their population'
Laura Ross +2 more
doaj +1 more source
Comparative pollination efficiency of freshly harvested pollen of Imperata cylindrica and Zea mays for haploid induction in bread wheat [PDF]
, 2016 Pollen viability is among the critical factors, which determine the success of a doubled haploidy breeding programme, thus the present investigation was undertaken to assess the functional viability and relative longevity of the pollen from Zea mays and ...
Badiyal, A. +3 more
core +1 more source
Exploring potential strategies for haploid induction based on double fertilization in plants. [PDF]
Plant Biotechnol JSummary Haploid induction (HI), an indispensable procedure in doubled haploid breeding, has attracted increasing attention in crop genetic improvement due to its ability to rapidly fix desirable traits in a homozygous state, thereby shortening the breeding cycle.
Li T +14 more
europepmc +2 more sources
Interspecific somatic hybrids between Solanum bulbocastanum and S. tuberosum and their haploidization for potato breeding. [PDF]
, 2012 Protoplast fusion between incongruent Solanum bulbocastanum and S. tuberosum haploids was accomplished to produce hybrids combining elite traits from both parents. We identified 11 somatic hybrids out of 42 regenerants analyzed through ISSR markers. Some
AVERSANO, RICCARDO +7 more
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