Results 1 to 10 of about 16,355 (160)
Hapten-Based Cancer Immunotherapy: From Immune Activation to Antitumor Activity [PDF]
CellsHapten-based immunotherapies represent a promising strategy to enhance the immunogenicity of tumor antigens and promote antitumor immune responses. Chemical conjugation of small haptens to antigens generates novel antigenic determinants that increase ...
Iseulys Richert +6 more
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Alternative Hapten Design for Zearalenone Immunoreagent Generation
Toxins, 2022 Appropriate hapten design and synthesis have been identified as critical steps to generate high-performance immunoreagents and to develop sensitive and selective immunoanalytical methods.
Antonio Abad-Fuentes +2 more
exaly +3 more sources
Development of a Polyclonal Antibody for the Immunoanalysis of Ochratoxin A (OTA) by Employing a Specially Designed Synthetic OTA Derivative as the Immunizing Hapten [PDF]
ToxinsWe report herein the development of a polyclonal antibody against ochratoxin A (OTA) using a specially designed synthetic OTA derivative as the immunizing hapten.
Chrysoula-Evangelia Karachaliou +4 more
doaj +2 more sources
A chemically contiguous hapten approach for a heroin–fentanyl vaccine
Beilstein Journal of Organic Chemistry, 2019 Background: Increased death due to the opioid epidemic in the United States has necessitated the development of new strategies to treat addiction. Monoclonal antibodies and antidrug vaccines provide a tool that both aids addiction management and reduces ...
Bin Zhou, Kim Janda, Lucy Lin
exaly +2 more sources
Walisongo Journal of Chemistry, 2020 Sejak isu kontaminasi melamin pada produk susu diketahui secara luas, diperlukan penelitian terbaru tentang teknik pemantauan yang cepat dan akurat untuk mendeteksi melamin dalam produk susu.
Leni Legasari
doaj +1 more source
Methods and Protocols, 2023 Development of a rapid detection method for deoxycholic acid (DCA) is crucial for its diagnosis in the early stages of inflammation and cancer.
Hiroshi Ueda, Hee-Jin Jeong
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Foods, 2023 Fenvalerate has the advantages of a broad insecticidal spectrum, high efficiency, low toxicity and low cost, and it is widely used in agriculture, especially in tea, resulting in the accumulation of fenvalerate residues in tea and the environment, posing
Kang Wei +5 more
doaj +1 more source
Hapten-conjugated polymeric nanocarriers produced by Flash NanoPrecipitation induce small molecule-specific antibodies in vivo [PDF]
RSC PharmaceuticsVaccines that induce antibodies specific against small molecules are desirable for a range of applications, including as a tool against the opioid epidemic. Many small molecules are not immunogenic due to their low molecular weight, but can be conjugated
Mojhdeh Baghbanbashi +6 more
doaj +1 more source
Molecules, 2010 Five generic haptens of pyrethoid insecticides, which were classified as three types, were designed and synthesized: the first (hapten 1) is for type I pyrethroids without a cyano group, the second (hapten 2 and XQ) for type II pyrethroids with a cyano ...
Peiwu Li +3 more
doaj +1 more source
Frontiers in Immunology, 2021 Neoantigen formation due to the interaction of drug molecules with human leukocyte antigen (HLA)-peptide complexes can lead to severe hypersensitivity reactions.
Montserrat Puig +18 more
doaj +1 more source