Results 11 to 20 of about 21,916 (222)

Structural Analysis of Anti-Hapten Antibodies to Identify Long-Range Structural Movements Induced by Hapten Binding [PDF]

Frontiers in Molecular Biosciences, 2021
Antibodies are well known for their high specificity that has enabled them to be of significant use in both therapeutic and diagnostic applications. Antibodies can recognize different antigens, including proteins, carbohydrates, peptides, nucleic acids ...
Mohammed M. Al Qaraghuli, Mohammed M. Al Qaraghuli, Karina Kubiak-Ossowska, Karina Kubiak-Ossowska, Valerie A. Ferro, Paul A. Mulheran   +5 more
doaj   +4 more sources

Simple Method for Preparation of Fluor/Hapten-Labeled dUTP

BioTechniques, 2000
Many projects, such as multiplex-fluorescence in situ hybridization (M-FISH) karyotyping, require the use of relatively large amounts of multiple fluor- or hapten-labeled nucleotides for the preparation of DNA probes.
Manjunath Nimmakayalu, Octavian Henegariu, David C. Ward, Patricia Bray-Ward   +3 more
doaj   +2 more sources

Hapten-enhanced overall survival time in advanced hepatocellular carcinoma by ultro-minimum incision personalized intratumoral chemoimmunotherapy

Journal of Hepatocellular Carcinoma, 2015
Feng Gao,2 Peng Jing,2 Jian Liu,2 Yuanfei Lu,1 Peicheng Zhang,2 Wei Han,1 Guoliang Liu,1 Ning Ru,2 Guanghui Cui,2 Chenglin Sun,1 Yebing Che,1 Huaming Zhang,1 Qnglong Hu,3 Huan-you Wang,4 Yingli Wu,2 Changjiang Guan,2 Qiang Fu,1 Zhenlu Ma,2 Baofa Yu1 ...
Gao F, Jing P, Liu J, Lu YF, Zhang PC, Han W, Liu GL, Ru N, Cui GH, Sun CL, Che YB, Zhang HM, Hu QL, Wang HY, Wu YL, Guan CJ, Fu Q, Ma ZL, Yu BF   +18 more
doaj   +1 more source

Hapten-enhanced therapeutic effect in advanced stages of lung cancer by ultra-minimum incision personalized intratumoral chemoimmunotherapy therapy

Lung Cancer: Targets and Therapy, 2015
Baofa Yu,1–3 Yuanfei Lu,1 Feng Gao,2 Peng Jing,2 Han Wei,1 Peicheng Zhang,2 Guoliang Liu,1 Ning Ru,2 Guanghui Cui,2 Xinhai Xu,1 Chenglin Sun,1 Changjiang Guan,2 Yebing Che,1 Yingli Wu,2 Zhenlu Ma,2 Qiang Fu,1 Jian Liu,2 Huan-You Wang4 1Jinan Baofa ...
Yu BF, Lu YF, Gao F, Jing P, Han W, Zhang PC, Liu GL, Ru N, Cui GH, Xu XH, Sun CL, Guan CJ, Che YB, Wu YL, Ma ZL, Fu Q, Liu J, Wang HY   +17 more
doaj   +1 more source

Role of hydrophobic interaction in hapten-antibody binding [PDF]

, 1977
The precipitation reaction of bovine serum albumin coupled with p-azophenylleucine with homologous antibody was inhibited by several structurally related haptens. The isobutyl group substituent on alpha-carbon atom of the leucine residue contributed more
Oda, Takuzo, Tsutsui, Ken, Hayashi, Hideo, Hatase, Osamu, Koide, Noriko, Tomoda, Jun   +5 more
core   +1 more source

Obtaining a Monoclonal Antibody against a Novel Prometryn-Like Hapten and Characterization of Its Selectivity for Triazine Herbicides

Biosensors, 2022
In this study, a previously unreported 3-((4-(isopropylamino)-6-(methylthio)-1,3,5-triazin-2-yl) amino) butyric acid hapten was designed and synthesized.
Lingyuan Xu, A. M. Abd El-Aty, Jing Zhao, Xingmei Lei, Xiuyuan Zhang, Yun Zhao, Xueyan Cui, Yongxin She, Fen Jin, Jing Wang, Maojun Jin, Bruce D. Hammock   +11 more
doaj   +1 more source

Charakterisierung von Immunseren durch Bindung von monovalentem Penicilloylhapten

CHIMIA, 1976
The preparation of tritium-labeled Nβ-benzylpenicilloylalanine and its use as a monovalent hapten in binding studies is described. The binding of 10-8M hapten to antisera of various species is readily performed but insufficient test sensitivity hampers ...
U. Otz, C.H. Schneider, A.L. de Weck
doaj   +1 more source

Synthesis of a psilocin hapten and a protein-hapten conjugate

Journal of Pharmacy and Pharmacology, 2002
Abstract Derivatives of psilocin with ω-functionalized alkyl spacers in position 1 of the indole ring were synthesized as haptens for use in a radioimmunoassay. Whereas the psilocin analogues with a 3-aminopropyl and a 4-aminobutyl moiety at the indole nitrogen decomposed during synthesis, the analogous 3-carboxypropyl psilocin ...
Christian, Albers, Matthias, Lehr, Justus, Beike, Helga, Köhler, Bernd, Brinkmann   +4 more
openaire   +2 more sources

Modulating Linker Composition of Haptens Resulted in Improved Immunoassay for Histamine

Biomolecules, 2019
Histamine (HA) is an important food contaminant generated during food fermentation or spoilage. However, an immunoassay for direct (derivatization free) determination of HA has rarely been reported due to its small size to induce the desired antibodies ...
Lin Luo, Xiao-Qun Wei, Bao-Zhu Jia, Jin-Yi Yang, Yu-Dong Shen, Bruce Hammock, Jie-Xian Dong, Hong Wang, Hong-Tao Lei, Zhen-Lin Xu   +9 more
doaj   +1 more source

On the heterogenetic haptene.

Experimental Biology and Medicine, 1926
Abstract In attempting to purify the specific part of the heterogenetic haptene, present in alcoholic extracts of horse kidneys, fractions were obtained which are distinguished from the common lipoids by their solubility in water. The material of one fraction described recently3 is practically insoluble in alcohol, chloroform and ether ...
K Landsteiner, P A Levene
openaire   +1 more source