Results 21 to 30 of about 21,916 (222)

Synthesis and identification of the antigens for carbofuran

浙江大学学报. 农业与生命科学版, 2002
This study reported that the first compound, 2, 3-dihydro-2, 2-dimethyl-7-benfuranyl chloroformate (DDBC) was synthesized after using 2,3-dihydro-2,2-dimrthyl-7-benzofuranol reacted with CoCl2.
ZHU Guo-nian, WU Ying-liang, CHENG Jin-li   +2 more
doaj   +1 more source

Successful development of methodology for detection of hapten-specific contact hypersensitivity (CHS) memory in swine.

PLoS ONE, 2019
Hapten contact hypersensitivity (CHS) elicits a well-documented inflammation response that can be used to illustrate training of immune cells through hapten-specific CHS memory.
E J Putz, A M Putz, A Boettcher, S Charley, M Sauer, M Palmer, R Phillips, J Hostetter, C L Loving, J E Cunnick, C K Tuggle   +10 more
doaj   +1 more source

Hapten designs based on aldicarb for the development of a colloidal gold immunochromatographic quantitative test strip

Frontiers in Nutrition, 2022
The common carbamate insecticide aldicarb is considered one of the most acutely toxic pesticides. Herein, rational design was used to synthesize two haptens with spacers of different carbon chain lengths. The haptens were then used to immunize mice.
Hong Shen, Yuping Wan, Yuping Wan, Xiaosheng Wu, Xiaosheng Wu, Yu Zhang, Yu Zhang, Jingwen Li, Tingting Cui, Tingting Cui, Han Sun, Haifeng Cui, Haifeng Cui, Kailun He, Guangpeng Hui, Guangpeng Hui, Xu Chen, Xu Chen, Guoqiang Liu, Guoqiang Liu, Meihong Du   +20 more
doaj   +1 more source

Predictable Peptide Conjugation Ratios by Activation of Proteins with Succinimidyl Iodoacetate (SIA)

Methods and Protocols, 2017
The small heterobifunctional linker succinimidyl iodoacetate (SIA) was examined for the preparation of peptide–protein bioconjugates with predicable conjugation ratios.
Ioana M. Abbas, Timm Schwaar, Frank Bienwald, Michael G. Weller   +3 more
doaj   +1 more source

Patch Testing With a Brazilian Propolis Series. [PDF]

Contact Dermatitis
Contact Dermatitis, Volume 95, Issue 4, Page 416-418, October 2026.
de Groot AC, Ipenburg NA, Franken SM, Rustemeyer T.   +3 more
europepmc   +2 more sources

Characterization and Comparison of Ochratoxin A-Ovalbumin (OTA-OVA) Conjugation by Three Methods

Journal of Integrative Agriculture, 2014
In order to generate an antibody against a small hapten molecule, the hapten is cross-linked with carrier protein to make it immunogenic. In this study, the hapten (ochratoxin A, OTA) was coupled to ovalbumin (OVA) by an active ester reaction. To develop
Xi-chun WANG, Ming BAO, Jin-jie WU, Ying LUO, Liang-you MA, Ying WANG, Ai-hua ZHANG, Cheng-hua HE, Hai-bin ZHANG   +8 more
doaj   +1 more source

Rational design of a fluopyram hapten and preparation of bioconjugates and antibodies for immunoanalysis† [PDF]

RSC Advances, 2015
A fluopyram hapten was designed in which insignificant electronic and structural modifications were foreseen and all potentially interacting chemical moieties were maintained.
E. Ceballos-Alcantarilla, C. Agulló, A. Abad-Fuentes, A. Abad-Somovilla, J. V. Mercader   +4 more
doaj   +1 more source

Design, Synthesis, and In Vivo Evaluation of C1-Linked 4,5-Epoxymorphinan Haptens for Heroin Vaccines

Molecules, 2022
In our continuing effort to develop effective anti-heroin vaccines as potential medications for the treatment of opioid use disorder, herein we present the design and synthesis of the haptens: 1-AmidoMorHap (1), 1-AmidoMorHap epimer (2), 1 Amido ...
Agnieszka Sulima, Fuying Li, Jeffrey Brian Morgan, Phong Truong, Joshua F. G. Antoline, Therese Oertel, Rodell C. Barrientos, Oscar B. Torres, Zoltan Beck, Gregory H. Imler, Jeffrey R. Deschamps, Gary R. Matyas, Arthur E. Jacobson, Kenner C. Rice   +13 more
doaj   +1 more source

Synthesis of Polyclonal Antibodies against Aflatoxin B1

Makara Journal of Science, 2015
Polyclonal antibodies of aflatoxin B1 were successfully produced from New Zealand White female rabbits after immunization by the hapten of aflatoxin B1-carboxymethyl hydroxylamine hemihydrochloride (AFB1-CMO) conjugated with bovine serum albumin (BSA) as
Wiyogo Prio Wicaksono, Deni Samsudin Permana, Romsyah Maryam, Yasuaki Einaga   +3 more
doaj   +1 more source

Hapten-Induced Contact Hypersensitivity, Autoimmune Reactions, and Tumor Regression: Plausibility of Mediating Antitumor Immunity

Journal of Immunology Research, 2014
Haptens are small molecule irritants that bind to proteins and elicit an immune response. Haptens have been commonly used to study allergic contact dermatitis (ACD) using animal contact hypersensitivity (CHS) models.
Dan A. Erkes, Senthamil R. Selvan
doaj   +1 more source