Results 81 to 90 of about 9,252,196 (204)
ABSTRACT The present guideline updates the initial ESCD patch testing guideline, summarizing all aspects of patch testing for the diagnosis of contact allergy in patients suspected of suffering, or having been suffering, from allergic contact dermatitis or other delayed‐type hypersensitivity skin and mucosal conditions. Sections with brief descriptions
Wolfgang Uter +23 more
wiley +1 more source
Design Education as a Catalyst for Change
Designers play a role in shaping our world, both literally and figuratively. Human lives are spent interacting with designed artefacts, systems, and processes.
Mulder, Ingrid +9 more
core +1 more source
In the stony coral, Acropora tenuis, embryos and larvae have progenitor/undifferentiated cells. Undifferentiated‐like cells differentiate into the pharyngeal stomodeum at an early larval stage, and nerve progenitors possess the dual potential to differentiate into nerve cells and vacuolated hyaline cells, depending on the oral‐aboral position ...
Kaz Kawamura +2 more
wiley +1 more source
Design and Synthesis of Haptens for Application to the Preparation of Chiral 1,4-Dihydropyridines.
Lipase-catalyzed enzymatic hydrolysis of dimethyl esters of 1, 4-dihydropyridines to the monoester, which is an important intermediate for the synthesis of optically active 1, 4-dihydropyridines, does not proceed directly. This paper describes the design and synthesis of novel haptens having a phosphonate group containing the requisite oxyanionic ...
IKEDA, Kiyoshi +3 more
openaire +2 more sources
Protective and Pathogenic Antibodies to Citrullinated Antigens
ABSTRACT Autoimmune diseases start years before clinical onset. In rheumatoid arthritis (RA), autoantibodies to citrullinated proteins (ACPA) and to modified IgG (rheumatoid factors, RF) can be detected many years before the inflammatory attack on cartilaginous joints. It has been assumed that these antibodies are pathogenic.
Outi Sareila +5 more
wiley +1 more source
Germinal Center Selection and Plasma Cell Differentiation
ABSTRACT Germinal centers (GCs) are specialized microenvironments in which B cells undergo affinity maturation through iterative cycles of somatic hypermutation, proliferation and selection, generating antibodies with improved antigen‐binding properties.
Adrien Sprumont, Oliver Bannard
wiley +1 more source
Lung cancer remains one of today’s most deadly and intractable cancers. Non-small cell lung cancer (NSCLC) accounts for roughly 85% of lung cancers, with an extremely poor survival rate.
Rohan Arora, Venkat Krishnan
doaj +1 more source
Plasma Cell Selection and Migration in the Establishment of Long‐Lived Antibody Responses
ABSTRACT As B cells are activated and differentiate into plasma cells, they execute migration programs that allow them to traffic within secondary lymphoid tissues and reach the bone marrow, where they can mature as long‐lived plasma cells. Recent studies have revealed mechanisms underlying not only affinity‐driven but also isotype‐driven plasma cell ...
Wataru Ise +2 more
wiley +1 more source
Probing the Effects of Hapten Stability on Cocaine Vaccine Immunogenicity
Judicious hapten design has been shown to be of importance when trying to generate a viable vaccine against a drug of abuse. Hapten design has typically been predicated upon faithfully emulating the unique chemical architecture that each drug presents ...
Xiaoqing Cai (288275) +6 more
core +1 more source
Abstract BACKGROUND Atopic dermatitis (AD) is increasingly recognized as a systemic inflammatory disorder linked to intestinal immune and microbiome dysregulation. However, whether dietary galactomannan fibers can mitigate AD through coordinated modulation of the gut–skin axis remains unexplored.
Derrick Kakooza +6 more
wiley +1 more source

