Molecular Recognition of Haptens by T Cells: More Than One Way to Tickle the Receptor [PDF]
Haptens as low molecular chemicals compose a major percentage of the universe of allergens, particularly with respect to allergic contact dermatitis (ACD).
Gamerdinger, K. +4 more
core
Reactivity of contact allergenic haptens to amino acid residues in a model carrier peptide, and characterisation of formed peptide-hapten adducts [PDF]
The type of chemical reaction between hapten and carrier protein in the formation of a complete antigen in vivo giving rise to an allergic contact dermatitis (ACD, type IV allergy) is essentially unknown.
Hansson, Christian, +3 more
core +1 more source
An analysis method using simple instrumentation was developed to investigate isothiazolinones in cosmetic and household products in patch test investigations. Analysis showed that concentrations of benzisothiazolinone can be several orders of magnitude higher than those of chloromethylisothiazolinone/methylisothiazolinone in products to which skin ...
Anne Farbrot +8 more
wiley +1 more source
Beyond Starch: Towards a Scalable Potato Platform for Molecular Farming
Re‐engineering potato as a biosafe and host‐optimised platform for plant molecular farming by integrating intrinsic biological traits with targeted engineering strategies. ABSTRACT Thirty‐five years after the first recombinant protein was produced in potato and 30 years after clinical trials of edible vaccines from its tubers, the crop is being ...
Izabela Anna Chincinska +2 more
wiley +1 more source
Relation between structure and specificity of antibodies: nuclear magnetic resonance study of binding fluorine-19 labeled nitrophenyl haptens to myeloma immunoglobulins M315, M460, and X25 [PDF]
The relation between structure and specificity of antibodies has been explored by ^(19)F NMR studies of the binding of trifluoromethyl analogues of nitrophenyl haptens to the three mouse myeloma immunoglobulins M315, M460, and X25.
Hardy, R R +3 more
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In vitro analyses of immune responses to metal and organic haptens in humans with contact allergy [Elektronisk resurs] [PDF]
Contact allergy is one of the most common skin diseases with great social and economical impact. The origin and nature of contact allergens (haptens) capable of inducing T-cell mediated allergic reactions are diverse, ranging from organic molecules to ...
Skov, Lone, +3 more
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Structure-immunogenicity relationship of kresoxim-methyl regioisomeric haptens [PDF]
Kresoxim-methyl was one of the two first strobilurins to be discovered, and nowadays it is widely used as an antifungal agent in crop protection. Because of its low molecular weight and negligible structural complexity, the generation of antibodies to ...
Agulló, Consuelo +4 more
core +1 more source
Phycotoxins haptens synthesis for immunosensor elaboration [PDF]
Ces dernières années, différents épisodes d’intoxication ont touché les coquillages sur le littoral français et tout particulièrement les huîtres dans le Bassin d’Arcachon. Afin de venir en aide à la profession ostréicole, le Conseil Régional d’Aquitaine
Baco, Etienne
core
Evaluation of the Capacity of Dendritic Cells Derived from Cord Blood CD34+ Precursors to Present Haptens to Unsensitized Autologous T Cells In Vitro [PDF]
Langerhans cells play a key role in contact hypersensitivity reactions. The application of haptens on the skin leads to many modifications of these cells, including the increase of major histocompatibility complex II expression, allogeneic stimulation ...
Nathalie Rougier +7 more
core +1 more source
Thermodynamics of solution of haptens and cyclodextrin-hapten complexes in aqueous and non aqueous media. [PDF]
Thermodynamic parameters of solution (DeltaG°s, DeltaH°s, and DeltaS°s) of some haptens [ortho-, meta-, para-, 5-chloro-2-, 6-chloro-2-, 2-chloro-4- and 4-chloro-3- (parahydroxyphenylazo) sodium benzoate] and three cyclodextrins (Delta, Delta
Traboulssi, Rafic.
core +3 more sources

