Results 101 to 110 of about 9,284 (223)

Filaggrin deficiency confers a paracellular barrier abnormality that reduces inflammatory thresholds to irritants and haptens.

, 2009
BACKGROUND: Mutations in the human filaggrin gene (FLG) are associated with atopic dermatitis (AD) and are presumed to provoke a barrier abnormality.
Gunathilake, R, Hatano, Y, Mauro, T M, Silva, K A, Man, M Q, Hupe, M, Scharschmidt, T C, Sundberg, J P, Crumrine, D, et, al   +9 more
core   +2 more sources

Imunopatologia da dermatite de contato alérgica Immunopathology of allergic contact dermatitis

Anais Brasileiros de Dermatologia, 2011
A dermatite de contato alérgica é consequência de uma reação imune mediada por células T contra químicos de baixo peso molecular, denominados haptenos. É uma condição frequente que ocorre em todas as raças e faixas etárias e afeta a qualidade de vida de ...
Luis Eduardo Agner Machado Martins, Vitor Manoel Silva dos Reis   +1 more
doaj   +1 more source

Oral PHGG ameliorates atopic dermatitis‐like dermatitis with concurrent modulation of colonic IgA and cecal microbiota: implications for the gut–skin axis

Journal of the Science of Food and Agriculture, Volume 106, Issue 11, Page 6380-6394, 30 August 2026.
Abstract BACKGROUND Atopic dermatitis (AD) is increasingly recognized as a systemic inflammatory disorder linked to intestinal immune and microbiome dysregulation. However, whether dietary galactomannan fibers can mitigate AD through coordinated modulation of the gut–skin axis remains unexplored.
Derrick Kakooza, Hyeonjun Yu, Jonghyun Jeong, Jung Cheul Shin, Woo Jung Kim, Sung‐Kwon Moon, Hoon Kim   +6 more
wiley   +1 more source

Fisiopatologia da dermatite de contato alérgica: papel das células T CD8 efetoras e das células T CD4 regulatórias Update on the pathophysiology with special emphasis on CD8 effector T cells and CD4 regulatory T cells

Anais Brasileiros de Dermatologia, 2005
A dermatite de contato alérgica (DCA), também conhecida como hipersensibilidade de contato (HSC) é uma das dermatoses inflamatórias mais freqüentes, sendo caracterizada por eritema, pápulas e vesículas, seguidas de ressecamento e descamação.
Ana Hennino, Marc Vocanson, Cyril Chavagnac, Pierre Saint-Mezard, Bertrand Dubois, Dominique Kaiserlian, Jean-François Nicolas   +6 more
doaj   +1 more source

An on-line analytical approach for detecting haptens in Shuang-huang-lian powder injection

, 2017
Shuang-huang-lian powder injection (SHLPI) is a traditional Chinese medicine injection (TCMI) frequently used in the clinical treatment of faucitis, bronchitis, and other viral and bacterial infections of upper respiratory tract.
Xiaotian Zhang, Zongtao Lin, Lan, Yuexiang, Daidong Wang, Yuexiang Lan, Chen, Shizhong, Haixiu Jiang, Wang, Daidong, Lin, Zongtao, Wang, Hong, Zhang, Xiaotian, Hong Wang, Sun, Hongyang, Shizhong Chen, Jiang, Haixiu, Hongyang Sun   +15 more
core   +1 more source

Development of broad-spectrum immunoassay with monoclonal antibody to detect five eugenols and study of their molecular recognition mechanism

Food Chemistry: X
In this study, three eugenol fragment-containing haptens were synthesized, and a monoclonal antibody (mAb) selective for five commonly-found eugenol compounds (EUGs, i.e., eugenol, isoeugenol, methyl eugenol, methyl isoeugenol, and acetyl isoeugenol) was
Lin Luo, Rui-Yao Kang, Zhen-Xi He, Bao-Zhu Jia, Zi-Jian Chen, Hao Deng, Zhen-Lin Xu   +6 more
doaj   +1 more source

Structure-immunogenicity relationship of kresoxim-methyl regioisomeric haptens [PDF]

, 2015
Kresoxim-methyl was one of the two first strobilurins to be discovered, and nowadays it is widely used as an antifungal agent in crop protection. Because of its low molecular weight and negligible structural complexity, the generation of antibodies to ...
Agulló, Consuelo, Abad Somovilla, Antonio, Abad Fuentes, Antonio, Mercader Badia, Josep Vicent, López Moreno, Rosario   +4 more
core   +1 more source

J Allergy (Cairo)

Low molecular weight chemical (LMW) allergens are commonly referred to as haptens. Haptens must complex with proteins to be recognized by the immune system.

core  

A Lincomycin-Specific Antibody Was Developed Using Hapten Prediction, and an Immunoassay Was Established to Detect Lincomycin in Pork and Milk

Foods
Prolonged consumption of animal-derived foods containing high levels of lincomycin (LIN) residues can adversely impact human health. Therefore, it is essential to develop specific antibodies and immunoassay methods for LIN.
Yuhan Shang, Dandan Zhang, Yun Shen, Yuanhu Pan, Jing Wang, Yulian Wang   +5 more
doaj   +1 more source

Synthesis of Haptens and Conjugates for ELISAs of Phytoestrogens. Development of the Immunological Tests

, 2000
International audienceSeven carboxylic acid haptens of isoflavonoids were synthesized, with the spacer arm on the oxygen atom at the C7 position for one series, with formononetin, daidzein, equol, biochanin A, and genistein, and at the C8 position for a ...
Le Menn, Françoise, Babin, Pierre, Bennetau, Bernard, Le Houérou, Cyril, Bennetau-Pelissero, Catherine, Lamothe, Valérie   +5 more
core   +1 more source