Results 81 to 90 of about 8,480 (219)
Recognition of β-ketoalcohol-derived haptens by tailor-made antibodies [PDF]
Antibodies steamed from mice immunized towards three different conjugates do not recognize the β-ketoalcohol for which they have been elaborated. They however recognize the haptens, which bear the side chain linking them to the carrier proteins.
Billen, D. +3 more
core
This study identified multiple areas for improvement in the regulatory risk assessment process. Conclusions based on predictive sensitization data should be made with caution, read‐across data from known sensitizers should be utilized, and epidemiological and patient threshold data should be prioritized in decision‐making.
Mathias Krogh Pedersen +7 more
wiley +1 more source
Hapten-carrier interactions and their role in the production of monoclonal antibodies against hydrophobic haptens [PDF]
The coupling of haptens to carrier proteins is required for the generation of antihapten antibody response, To date, different polypeptides (such as gelatin, albumin, and keyhole limpet hemocyanin) have been used to increase the immune response against ...
Marini, S +6 more
core
Citation: 'hapten' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.H02738 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire +2 more sources
Changing Functionality of Surfaces by Directed Self-Assembly Using Oligonucleotides—The Oligo-Tag
A method is presented to modify surfaces for biotechnological applications. Oligonucleotides have been coupled covalently to a pre-activated surface. Complementary oligonucleotides hybridize to the surface, which are conjugated with functionalities.
Frank F. Bier +3 more
doaj +1 more source
An on-line analytical approach for detecting haptens in Shuang-huang-lian powder injection [PDF]
Shuang-huang-lian powder injection (SHLPI) is a traditional Chinese medicine injection (TCMI) frequently used in the clinical treatment of faucitis, bronchitis, and other viral and bacterial infections of upper respiratory tract.
Xiaotian Zhang +15 more
core +1 more source
A case series of eight patients with allergic otitis externa from contact allergy to hearing aid ear moulds is presented. All were patch test positive to tetrahydrofurfuryl methacrylate and three to isobornyl acrylate. It is postulated that these are likely relevant allergens present in such devices. ABSTRACT Background Allergic contact dermatitis from
Norbertus A. Ipenburg +2 more
wiley +1 more source
Autoimmunity and Periodontitis
In a microbe‐driven inflammatory environment, peptidyl‐arginine deiminase (PAD) enzymes from neutrophils and Porphyromonas gingivalis citrullinate both microbial and self‐antigens. B cell presentation of citrullinated or self‐mimicking epitopes activates T cells that assist B cells in antibody isotype switching, affinity maturation, epitope spreading ...
Massimo Costalonga +2 more
wiley +1 more source
NLRP3 Inflammasome and Allergic Contact Dermatitis: A Connection to Demystify
Allergic contact dermatitis is a common occupational disease that manifests as a cell-mediated hypersensitivity reaction following skin exposure to small reactive chemicals termed haptens.
Ana Isabel Sebastião +5 more
doaj +1 more source
Experts agree that patch test is nowadays the only validated method for the detection of contact allergy to haptens. Facing more than 5200 known haptens, starting with sensitizers most frequent in a given population seems most reasonable. Baseline series
Radosław Śpiewak +3 more
doaj +1 more source

