Results 91 to 100 of about 9,284 (223)
Protective and Pathogenic Antibodies to Citrullinated Antigens
ABSTRACT Autoimmune diseases start years before clinical onset. In rheumatoid arthritis (RA), autoantibodies to citrullinated proteins (ACPA) and to modified IgG (rheumatoid factors, RF) can be detected many years before the inflammatory attack on cartilaginous joints. It has been assumed that these antibodies are pathogenic.
Outi Sareila +5 more
wiley +1 more source
Delayed Hypersensitivity to Hapten-Protein Conjugates. III. Saccharides as Haptens.
SummaryConjugates of monosaccharide and disaccharide haptens to protein have been found to function adequately in the induction and elicitation of delayed hypersensitivity reactions in the guinea pig. The characteristics of these delayed responses paralleled those observed with other ionic and nonpolar haptens.
F, BOREK, A M, SILVERSTEIN, P G, GELL
openaire +2 more sources
Recognition of b-ketoalcohol-derived Haptens by Tailor-made antibodies.
Antibodies from mice immunized towards three' different conjugates do not recognize the b-ketoalc. for which they have been elaborated. They however recognize the haptens, which bear the side chain linking them to the carrier proteins.
Letesson, Jean-Jacques +3 more
core
Opioid-Based Haptens: Development of Immunotherapy
Over the past decades, extensive preclinical research has been conducted to develop vaccinations to protect against substance use disorder caused by opioids, nicotine, cocaine, and designer drugs. Morphine or fentanyl derivatives are small molecules, and
Karadi, David A. +11 more
core +1 more source
In vitro analyses of immune responses to metal and organic haptens in humans with contact allergy
Contact allergy is one of the most common skin diseases with great social and economical impact. The origin and nature of contact allergens (haptens) capable of inducing T-cell mediated allergic reactions are diverse, ranging from organic molecules to ...
Masjedi, Khosro
core +1 more source
Germinal Center Selection and Plasma Cell Differentiation
ABSTRACT Germinal centers (GCs) are specialized microenvironments in which B cells undergo affinity maturation through iterative cycles of somatic hypermutation, proliferation and selection, generating antibodies with improved antigen‐binding properties.
Adrien Sprumont, Oliver Bannard
wiley +1 more source
Recognition of β-ketoalcohol-derived haptens by tailor-made antibodies
Antibodies steamed from mice immunized towards three different conjugates do not recognize the β-ketoalcohol for which they have been elaborated. They however recognize the haptens, which bear the side chain linking them to the carrier proteins.
Billen, D. +3 more
core
A rapid method for monitoring DNA labelling reactions with haptens
A rapid and simple method for evaluating the efficiency of DNA labelling reactions with haptens is described. The method, called the Flow-Through Hapten-DNA Assay (FT-HDA), relies on binding of anti-hapten antibodies/alkaline phosphatase conjugates to ...
A. Corti +5 more
core +1 more source
Patch Testing With a Brazilian Propolis Series
Contact Dermatitis, Volume 95, Issue 4, Page 416-418, October 2026.
Anton C. de Groot +3 more
wiley +1 more source
Plasma Cell Selection and Migration in the Establishment of Long‐Lived Antibody Responses
ABSTRACT As B cells are activated and differentiate into plasma cells, they execute migration programs that allow them to traffic within secondary lymphoid tissues and reach the bone marrow, where they can mature as long‐lived plasma cells. Recent studies have revealed mechanisms underlying not only affinity‐driven but also isotype‐driven plasma cell ...
Wataru Ise +2 more
wiley +1 more source

