Results 91 to 100 of about 8,480 (219)

FLUORESCENCE RESONANCE ENERGY-TRANSFER ON SINGLE LIVING CELLS - APPLICATION TO BINDING OF MONOVALENT HAPTENS TO CELL-BOUND IMMUNOGLOBULIN-E [PDF]

open access: yes, 1991
We have determined the specific binding of 2,4-dinitrophenyl (DNP)-haptens to two different monoclonal immunoglobulin (IgE) molecules bound to Fc epsilon-receptors on the cell surface of single, living rat basophilic leukemia cells subclone 2H3 cells ...
Kircheis, M.   +8 more
core   +1 more source

Oral PHGG ameliorates atopic dermatitis‐like dermatitis with concurrent modulation of colonic IgA and cecal microbiota: implications for the gut–skin axis

open access: yesJournal of the Science of Food and Agriculture, Volume 106, Issue 11, Page 6380-6394, 30 August 2026.
Abstract BACKGROUND Atopic dermatitis (AD) is increasingly recognized as a systemic inflammatory disorder linked to intestinal immune and microbiome dysregulation. However, whether dietary galactomannan fibers can mitigate AD through coordinated modulation of the gut–skin axis remains unexplored.
Derrick Kakooza   +6 more
wiley   +1 more source

Contact sensitisers activate keratinocytes and induce cytotoxicity via Transient Receptor Potential Ankyrin 1 in allergic contact dermatitis

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 16, Page 4610-4627, August 2026.
Abstract Background and Purpose Allergic contact dermatitis (ACD) is a frequent inflammatory skin disease with limited therapeutic options. While neuronal Transient Receptor Potential Ankyrin 1 (TRPA1) has been implicated in ACD, the role of keratinocyte TRPA1 remains unclear.
Areej Jaber   +8 more
wiley   +1 more source

Immunoassay Development for the Class-Specific Assay for Types I and II Pyrethroid Insecticides in Water Samples

open access: yesMolecules, 2010
Five generic haptens of pyrethoid insecticides, which were classified as three types, were designed and synthesized: the first (hapten 1) is for type I pyrethroids without a cyano group, the second (hapten 2 and XQ) for type II pyrethroids with a cyano ...
Peiwu Li   +3 more
doaj   +1 more source

Absorption and Effects of Patch Test Preparations of Hydroperoxides of Limonene and Hydroperoxides of Linalool in Human Ex Vivo Skin

open access: yesContact Dermatitis, Volume 95, Issue 2, Page 159-168, August 2026.
This study mimics clinical patch testing for the diagnosis of allergic contact dermatitis, by application of patch test preparations of fragrance terpenes to ex vivo human skin samples. The study investigates the penetration of linalool hydroperoxide and limonene hydroperoxide in skin, alongside an analysis of the lipid‐modifying effects of the patch ...
Aoife Clancy   +3 more
wiley   +1 more source

Delayed Hypersensitivity to Hapten-Protein Conjugates. III. Saccharides as Haptens.

open access: yesExperimental Biology and Medicine, 1963
SummaryConjugates of monosaccharide and disaccharide haptens to protein have been found to function adequately in the induction and elicitation of delayed hypersensitivity reactions in the guinea pig. The characteristics of these delayed responses paralleled those observed with other ionic and nonpolar haptens.
F, BOREK, A M, SILVERSTEIN, P G, GELL
openaire   +2 more sources

J Allergy (Cairo) [PDF]

open access: yes
Low molecular weight chemical (LMW) allergens are commonly referred to as haptens. Haptens must complex with proteins to be recognized by the immune system.

core  

In vitro analyses of immune responses to metal and organic haptens in humans with contact allergy [PDF]

open access: yes, 2008
Contact allergy is one of the most common skin diseases with great social and economical impact. The origin and nature of contact allergens (haptens) capable of inducing T-cell mediated allergic reactions are diverse, ranging from organic molecules to ...
Masjedi, Khosro
core  

The Dual Role of Preexisting Immunity in Influenza: Protective Recall Versus Constraint of Novel Responses

open access: yesImmunological Reviews, Volume 341, Issue 1, August 2026.
ABSTRACT Preexisting immunity to influenza confers rapid protection against antigenically matched viruses but can also constrain responses to drifted variants. This review asks when and why prior infection or vaccination is protective versus detrimental, and which biological mechanisms—epitope masking by circulating antibody, inhibitory FcγRIIb ...
Annette Fox   +2 more
wiley   +1 more source

Reverse design of haptens based on antigen spatial conformation to prepare anti-capsaicinoids&gingerols antibodies for monitoring of gutter cooking oil

open access: yesFood Chemistry: X
Rapid simultaneous detection of multi-component adulteration markers can improve the accuracy of identification of gutter cooking oil in edible oil, which is made possible by broad-spectrum antibody (bs-mAb).
Kunying Nie   +7 more
doaj   +1 more source

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