Results 151 to 160 of about 1,956 (188)
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Metabolism of harmaline in rats
Biochemical Pharmacology, 1971Abstract The distribution and metabolic fate of [3H]harmaline-HCl were studied in rats. Thirty min after subcutaneous injection, high radioactivity was found in the small intestine, liver, adrenals, kidneys and lungs. A rapid turnover and elimination was evident after the first hour, as most of the tissues, except the liver, kidneys and intestines ...
B T, Ho +5 more
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The effect of harmaline on intestinal sodium transport and on sodium-dependentd-glucose transport in brush-border membrane vesicles from rabbit jejunum [PDF]
Pflugers Archiv European Journal of Physiology, 1979 Harmaline inhibition of sodium uptake and of sodium-dependentd-glucose transport was investigated using brush-border membrane vesicles from frozen rabbit jejunum.
F Alvarado, Murer Heini
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Exacerbation of harmaline-induced tremor by imipramine
Pharmacology Biochemistry and Behavior, 2005Imipramine is a well-established tricyclic antidepressant which was first approved for the treatment of depression in the late fifties. Antidepressant effect of imipramine is attributed to inhibition of serotonin (5HT) and noradrenaline (NA) reuptake in brain. These monoamines have been implicated in a variety of neurological disorders including tremor.
Mohammed, Arshaduddin +4 more
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Canadian Journal of Chemistry, 1959
The synthesis of 1-methyl-3,4-dihydro-β-carboline (harmalan) and of two of its derivatives by dehydration of the corresponding 1-hydroxymethyl-1,2,3,4-tetrahydro-β-carbolines is described. Harmalan was also obtained by oxidative decarboxylation of 1-methyl-1,2,3,4-tetrahydro-β-carboline-1-carboxylic acid.
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The synthesis of 1-methyl-3,4-dihydro-β-carboline (harmalan) and of two of its derivatives by dehydration of the corresponding 1-hydroxymethyl-1,2,3,4-tetrahydro-β-carbolines is described. Harmalan was also obtained by oxidative decarboxylation of 1-methyl-1,2,3,4-tetrahydro-β-carboline-1-carboxylic acid.
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, 2005 Although tremor is a common sign of neurological disorders, such as Parkinson\u27s disease, Wilson\u27s disease, and hereditary ataxia, most adults with clinically significant tremor have idiopathic or essential tremor (ET).
MARK LeDOUX, LeDoux, Mark
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Effect of harmaline on the cerebello-rubral system
Experientia, 1977Harmaline induces synchronous rhythms in both the cerebellum and the red nucleus of the rabbit. The level of synchronization is lower in the red nucleus than in the cerebellar cortex, probably because the cerebello-rubral pathway and the red nucleus neurons only participate poorly in the harmaline-induced olivo-cerebellar rhythm.
G, Gogolák, R, Jindra, C, Stumpf
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Effects of harmaline on the visual system of the rat
Vision Research, 1971Abstract Harmaline is a potent hallucinogenic drug as demonstrated by clinical studies. The purpose of this work was to study the effect of Harmaline on some electrophysiological responses at various levels of the rat visual system. The intravenous injection of 2 mg/kg provokes typical changes of the ERG in the albino rat.
A, Rojas +3 more
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Facilitating effect of harmaline on the aortic response to dopamine
Pharmacological Research, 1992[No abstract available]
PALMERY, Maura +3 more
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Harmaline, a potent inhibitor of sodium-dependent transport
Biochimica et Biophysica Acta (BBA) - Biomembranes, 1974Abstract Harmaline, a hallucinogenic alkaloid, inhibits sugar and amino acid transport by the guinea-pig intestinal mucosa in vitro during short and long incubations. It affects sodium-dependent transport systems in other tissues such as the dog colonic mucosa and renal cortex slices, but does not influence sodium-independent transport.
F V, Sepúlveda, J W, Robinson
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Baclofen attenuates harmaline induced tremors in rats
Neuroscience Letters, 2001Recent experimental and clinical studies clearly suggest the role of gamma-aminobutyric acid (GABA) in the pathogenesis of tremors. The present study was undertaken to investigate the effect of baclofen, a GABA B receptor agonist on harmaline induced tremors.
M, Tariq +4 more
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