Results 81 to 90 of about 73,078 (260)
Plants, 2019 Triticale is a relatively new crop which still possesses serious drawbacks that can be significantly improved by breeding. The dwarfing genes proved to be very useful in the development of new lodging resistant and productive cultivars of winter ...
Pavel Kroupin +4 more
doaj +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Interdependence of yield components and harvest index in sunflower [PDF]
, 2001 Using correlation analysis, we studied the interrelationship between several yield components (grain yield, head diameter, plant height, and the dry matter mass of the stem, leaves, head, and vegetative plant parts) and the harvest index in five female sunflower lines, three male lines (testers), and their 15 F1 hybrids.
Joksimović, Jovan +3 more
openaire
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
High-yield factors in the new soybean cultivar ‘Soramizuki’ derived from a US parent cultivar
Plant Production ScienceA new soybean cultivar, ‘Soramizuki,’ was developed by crossing ‘Fukuyutaka A1 gou’ with ‘UA4805’ to integrate the high-yield characteristics of a US cultivar into a Japanese cultivar.
Ryo Yamazaki +8 more
doaj +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
The Other Mechanisms by Which the Rht Genes Improve the Harvest Index of Wheat. [PDF]
Plants (Basel), 2022 Ukozehasi C, Ober ES, Griffiths H.
europepmc +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
PlantsFlax (Linum usitatissimum L.) is a retrovative crop with highly nutritious seeds. The study aimed to assess the effect of plant density and type of fertilizer on crop growth and productivity.
Panteleimon Stavropoulos +7 more
doaj +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source