Results 41 to 50 of about 11,390 (192)

The role of the multifaceted long non-coding RNAs: A nuclear-cytosolic interplay to regulate hyaluronan metabolism

open access: yesMatrix Biology Plus, 2021
In the extracellular matrix (ECM), the glycosaminoglycan (GAG) hyaluronan (HA) has different physiological roles favouring hydration, elasticity and cell survival.
Arianna Parnigoni   +6 more
doaj   +1 more source

Hypoxia promotes redifferentiation and suppresses markers of hypertrophy and degeneration in both healthy and osteoarthritic chondrocytes [PDF]

open access: yes, 2013
INTRODUCTION: Hypoxia is considered to be a positive influence on the healthy chondrocyte phenotype and cartilage matrix formation. However, hypoxia-inducible factors (HIFs) have been implicated in the pathogenesis of osteoarthritis (OA).
Brandon D Markway   +2 more
core   +1 more source

Attenuated Replication-Competent Herpes Simplex Virus Expressing an ECM-Modifying Transgene Hyaluronan Synthase 2 of Naked Mole Rat in Oncolytic Gene Therapy

open access: yesMicroorganisms, 2023
Herpes simplex virus (HSV) has proven successful in treating human cancer. Since the approval of talimogene laherparepvec (T-VEC) in 2015, HSV has been thoroughly researched to discover novel mechanisms to combat cancer and treat other diseases.
Jussi Palomäki   +7 more
doaj   +1 more source

Dynamic interplay between breast cancer cells and normal endothelium mediates the expression of matrix macromolecules, proteasome activity and functional properties of endothelial cells [PDF]

open access: yes, 2014
Background Breast cancer\u2013endothelium interactions provide regulatory signals facilitating tumor progression. The endothelial cells have so far been mainly viewed in the context of tumor perfusion and relatively little is known regarding the effects ...
Barbouri, D.   +5 more
core   +1 more source

Cell density dependent stimulation of PAI-1 and hyaluronan synthesis by TGF-[béta] in orbital fibroblasts [PDF]

open access: yes, 2018
L
Berta, Eszter   +10 more
core   +1 more source

Reducing data processing effort in camera trap density estimation: Extending the REST model by explicitly modelling animal detection processes

open access: yesMethods in Ecology and Evolution, EarlyView.
Abstract Accurate and reliable estimation of wildlife population density is fundamental to effective conservation and management. While camera traps show potential for monitoring ground‐dwelling mammal densities, labour‐intensive data processing remains a significant constraint. Ideally, conservation efforts would benefit from the continuous monitoring
Yoshihiro Nakashima   +2 more
wiley   +1 more source

Value of long non-coding RNA HAS2-AS1 as a diagnostic and prognostic marker of glioma

open access: yesNeurología (English Edition)
Background: Glioma presents high incidence and poor prognosis, and therefore more effective treatments are needed. Studies have confirmed that long non-coding RNAs (lncRNAs) basically regulate various human diseases including glioma.
A. You   +9 more
doaj   +1 more source

The asymptotic behavior of Frobenius direct images of rings of invariants [PDF]

open access: yes, 2015
We define the Frobenius limit of a module over a ring of prime characteristic to be the limit of the normalized Frobenius direct images in a certain Grothendieck group.
Hashimoto, Mitsuyasu, Symonds, Peter
core   +3 more sources

Examining the Effects of Synchronous Written Corrective Feedback During Computer‐Mediated Collaborative Writing: Feedback Type and Learner Perceptions

open access: yesInternational Journal of Applied Linguistics, EarlyView.
ABSTRACT Spurred by the advancement of educational technology, more language instruction has been offered in online environments. Consequently, teaching practices have had to adapt to digital platforms. Accordingly, teachers’ provision of synchronous written corrective feedback (SWCF) on digital texts has received increasing attention.
Sanghee Kang, YouJin Kim, Minkyung Kim
wiley   +1 more source

Hyaluronic acid, HAS1, and HAS2 are significantly upregulated during muscle hypertrophy

open access: yesAmerican Journal of Physiology-Cell Physiology, 2012
Hyaluronic acid (HA) is a component of the extracellular matrix (ECM) in most vertebrate tissues and is thought to play a significant role during development, wound healing, and regeneration. In vitro studies have shown that HA enhances muscle progenitor cell recruitment and inhibits premature myotube fusion, implicating a role for this ...
Sarah, Calve   +3 more
openaire   +3 more sources

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