Results 61 to 70 of about 6,032 (200)

Elevated expression of hyaluronan synthase 2 associates with decreased survival in diffusely infiltrating astrocytomas

BMC Cancer, 2018
Background Diffusely infiltrating astrocytomas originate from astrocytic glial cells or their precursor cells and are the most common type of brain tumors in adults. In this retrospective study, we investigated the content of hyaluronan, its cell surface
Mari Valkonen, Hannu Haapasalo, Kirsi Rilla, Kristiina Tyynelä-Korhonen, Ylermi Soini, Sanna Pasonen-Seppänen   +5 more
doaj   +1 more source

Immunohistochemical stainings of pancreatic cancer tissues with hyaluronan (HA), HAS2, and HYAL1.

, 2013
Stainings of HA, HAS2, and HYAL1 were found in the cytoplasm. (HA) Weak and strong HA staining patterns of tumor and stromal cells in pancreatic cancer. (HAS2) Weak and strong HAS2 staining patterns of tumor cells in pancreatic cancer.
Koji Yamaguchi (93289), Norihiro Sato (243902), Xiao-Bo Cheng (482687), Shiro Kohi (482688)   +3 more
core   +1 more source

Hyaluronic acid: A novel approach in regenerative/reconstructive periodontal therapy?

Periodontology 2000, EarlyView.
Abstract Background Although hyaluronic acid (HA) has long been used for many medical applications, only in recent years has it gained greater popularity in the field of periodontics because of its biological effects during wound healing. Even today, most clinicians are not aware that more than one type of HA exists and that the extent of its ...
Andrea Pilloni, Yoshinori Shirakata, Lorenzo Marini, Darko Božić, Richard J. Miron, Roberto Rotundo, Andreas Stavropoulos, Anton Sculean   +7 more
wiley   +1 more source

Hyaluronic acid, HAS1, and HAS2 are significantly upregulated during muscle hypertrophy

American Journal of Physiology-Cell Physiology, 2012
Hyaluronic acid (HA) is a component of the extracellular matrix (ECM) in most vertebrate tissues and is thought to play a significant role during development, wound healing, and regeneration. In vitro studies have shown that HA enhances muscle progenitor cell recruitment and inhibits premature myotube fusion, implicating a role for this ...
Sarah, Calve, Jahdonna, Isaac, Jonathan P, Gumucio, Christopher L, Mendias   +3 more
openaire   +3 more sources

PFKFB4 Promotes Breast Cancer Metastasis via Induction of Hyaluronan Production in a p38-Dependent Manner

Cellular Physiology and Biochemistry, 2018
Background/Aims: The bi-functional enzyme 6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase-4 (PFKFB4) is highly expressed in many types of cancer and its requirement for tumor survival has been demonstrated in glioma, lung, and prostate cancers ...
Ruifang Gao, Yanhua Liu, Dan Li, Jing Xun, Wei Zhou, Peng Wang, Chen Liu, Xiru Li, Wenzhi Shen, Weijun Su, Huan Qiao, Dwayne G. Stupack, Na Luo   +12 more
doaj   +1 more source

Understanding exosomes in facial esthetics and skin aging

Periodontology 2000, EarlyView.
Abstract Background Skin aging is a multifactorial process mediated by intrinsic (genetic and metabolic) and extrinsic (environmental) factors leading to functional and structural deterioration, including wrinkles, loss of collagen and elastin, as well as various pigmentation disorders.
Richard J. Miron, Catherine Davies, Anton Sculean, Paras Ahmad   +3 more
wiley   +1 more source

Sirtuin 1 reduces hyaluronan synthase 2 expression by inhibiting nuclear translocation of NF-kB and expression of the long-non coding RNA HAS2-AS1 [PDF]

, 2020
Hyaluronan (HA) is one of the most prevalent glycosaminoglycans of the vascular extracellular matrix (ECM). Abnormal HA accumulation within blood vessel walls is associated with tissue inflammation and is prominent in most vascular pathological ...
Vitale, Daiana L, Manuela Viola, Parnigoni, Arianna, Hascall, Vincent C, Passi, Alberto, Daiana L. Vitale, Bartolini, Barbara, Ilaria Caon, Caon, Ilaria, De Luca, Giancarlo, Karousou, Evgenia, Alberto Passi, Vigetti, Davide, Hascall, Vincent C., Elena Caravà, Alaniz, Laura, Barbara Bartolini, Giancarlo De Luca, Arianna Parnigoni, Laura Alaniz, Vincent C. Hascall, Moretto, Paola, Viola, Manuela, Evgenia Karousou, Vitale, Daiana Luján, Paola Moretto, Caravà, Elena, Davide Vigetti, Alaniz, Laura Daniela   +28 more
core   +1 more source

Fertilization influences overyielding through dominance of species with high specific leaf area in young tree mixtures

Functional Ecology, Volume 40, Issue 6, Page 1755-1775, June 2026.
Read the free Plain Language Summary for this article on the Journal blog. Abstract In the context of anthropogenic eutrophication of the biosphere, understanding the impact of nutrient addition on plant diversity–productivity relationships remains a major challenge.
Dai F. Saito, Friderike Beyer, Grégoire T. Freschet, Anja Klingler, Charles A. Nock, Peter B. Reich, Michael Scherer‐Lorenzen, Jürgen Bauhus   +7 more
wiley   +1 more source

Assessing D‐Squame as a Minimally Invasive Technique to Evaluate the Cutaneous Immune Response mRNA in a Dog Model of Canine Atopic Dermatitis

Veterinary Dermatology, Volume 37, Issue 3, Page 353-364, June 2026.
ABSTRACT Background Canine atopic dermatitis (cAD) is a multifactorial, inherited skin disease, estimated to affect ≤ 15% of dogs. Studies of skin messenger mRNA in cAD currently use invasive methods, including blood sampling and biopsy collection, whilst advances in human atopic dermatitis study methodology have demonstrated reliable use of minimally ...
Xavier Langon, Marion Mosca, Nadège Milhau, Mélanie Legain, Adrien Idée, Didier Pin   +5 more
wiley   +1 more source

Growth promoting effect of hyaluronan synthesis promoting substances on Japanese eel leptocephali. [PDF]

PLoS ONE, 2014
Hyaluronans (HAs) are glycosaminoglycans produced in the bodies of Anguilliform and Elopiform leptocephali, and play a role in metabolic energy. In mammals, HA synthesis-promoting substances (HASPS) up-regulate the expression of HA synthase (HAS) and ...
Yutaka Kawakami, Kazuharu Nomura, Hideki Tanaka   +2 more
doaj   +1 more source