Results 81 to 90 of about 5,167 (169)

Metastatic tumor growth in steatotic liver is promoted by HAS2-mediated fibrotic tumor microenvironment

The Journal of Clinical Investigation
Steatotic liver enhances liver metastasis of colorectal cancer (CRC), but this process is not fully understood. Steatotic liver induced by a high-fat diet increases cancer-associated fibroblast (CAF) infiltration and collagen and hyaluronic acid (HA ...
Yoon Mee Yang, Jieun Kim, Zhijun Wang, Jina Kim, So Yeon Kim, Gyu Jeong Cho, Jee Hyung Lee, Sun Myoung Kim, Takashi Tsuchiya, Michitaka Matsuda, Vijay Pandyarajan, Stephen J. Pandol, Michael S. Lewis, Alexandra Gangi, Paul W. Noble, Dianhua Jiang, Akil Merchant, Edwin M. Posadas, Neil A. Bhowmick, Shelly C. Lu, Sungyong You, Alexander M. Xu, Ekihiro Seki   +22 more
doaj   +1 more source

Hyaluronan synthase 2 (HAS2) [PDF]

Science-Business eXchange, 2011
openaire   +1 more source

Hyaluronan network remodeling by ZEB1 and ITIH2 enhances the motility and invasiveness of cancer cells

The Journal of Clinical Investigation
Hyaluronan (HA) in the extracellular matrix promotes epithelial-mesenchymal transition (EMT) and metastasis; however, the mechanism by which the HA network constructed by cancer cells regulates cancer progression and metastasis in the tumor ...
Sieun Lee, Jihye Park, Seongran Cho, Eun Ju Kim, Seonyeong Oh, Younseo Lee, Sungsoo Park, Keunsoo Kang, Dong Hoon Shin, Song Yi Ko, Jonathan M. Kurie, Young-Ho Ahn   +11 more
doaj   +1 more source

Epigenetic HAS2 promoter regulation

Report on the experimental results of epigenetic HAS2 promoter regulation.
openaire   +1 more source

Hyaluronan Regulates Vascular Smooth Muscle Cell Osteogenic Differentiation and Vascular Calcification. [PDF]

Biomolecules
Roy S, Kane J, Grigorieva I, Roche-Dugmore D, Moore S, Steadman R, Raby AC, Jakulj L, Schurgers L, Lutgens E, Eringa EC, Vervloet M, Fraser D, Meran S.   +13 more
europepmc   +1 more source

Orcinol glucoside ameliorates pulmonary fibrosis by suppressing hyaluronic acid synthesis and macrophage M2 polarization via targeting hyaluronic acid synthase 2. [PDF]

Int J Mol Med
Li C, Tang X, Luo X, Lai X, Yang J, Xu Z, Muhetaer G, Xie Y, Huang X, Li H.   +9 more
europepmc   +1 more source

Salidroside Ameliorates Polycystic Ovary Syndrome in Mice by Regulating the AKT/NF-κB/NLRP3-HAS2 Axis. [PDF]

Food Sci Nutr
Li JH, Shi SM, Liu LY, He YY, Jia GL, Qu LY, Chi ZC, Leng JH, Xu HJ, Lan T, Yan DL, Kong IK, Yu XF, Zhang MJ, Jin YX.   +14 more
europepmc   +1 more source

Bioinformatics approach to identifying molecular targets of Danlou tablet against atherosclerosis: a machine learning pharmacology study. [PDF]

Naunyn Schmiedebergs Arch Pharmacol
Wang L, Zhang M, Wang H, Peng S, Liang X, Li G, Xu D.   +6 more
europepmc   +1 more source

Extracellular matrix mediates circulating tumor cell clustering in triple-negative breast cancer metastasis. [PDF]

Nat Commun
Bobkov GO, Patel KJ, Lege BM, Zheng R, Shaulsky G, Ellis MJ, Cheng C.   +6 more
europepmc   +1 more source

Epigenetic Regulation of Hyaluronan-Associated Genes in the Brain: Identifying Key Regulatory Sites. [PDF]

Epigenomes
Acevedo RE, Walton E, Mifsud KR.
europepmc   +1 more source