Results 141 to 150 of about 60,915 (280)
Primary Cancer Prevention Through Vaccination: Advances, Challenges, and Global Perspectives
ABSTRACT Oncogenic viral and bacterial infections constitute a significant portion of the global cancer burden, accounting for up to 15% of cases, particularly in low‐ and middle‐income countries. Prophylactic vaccination thus appears to be the most effective tool for preventing these preventable cancers, especially those linked to human papillomavirus
Christian Tague +5 more
wiley +1 more source
ABSTRACT Background Hepatitis B virus (HBV) infection is a major occupational hazard among healthcare workers (HCWs), particularly in resource‐limited settings where vaccination coverage remains low. This study aimed to assess hepatitis B vaccination coverage and associated factors among healthcare workers.
Melaku Zewdu Yehualaw +7 more
wiley +1 more source
HBsAg+ and HBsAg- Chronic Active Hepatitis, Liver Cirrhosis and Hepatocellular Carcinoma in Korea:Prevalence and Difference in Age Distribution [PDF]
Korea is one of the endemic areas of hepatitis B virus infection. In clinical practice, we have suspected that HBsAg+ patients with chronic liver disease (CLD) are younger than HBsAg - patient.
Kim, Chung Yong +2 more
core
Primary hepatic cancer (PHC), especially hepatocellular carcinoma (HCC), is still a significant burden worldwide. The efficacy of diagnosis, treatment response monitoring, and prognostication using laboratory biomarkers is still a challenge. This study analyzed multi‐laboratory parameters pre‐ and post‐treatment and their associations with clinical and
Xiaowei Chi +3 more
wiley +1 more source
CMAISE: Establishing the Longitudinal Multi‐Omics Cohort for Sepsis Precision Medicine
ABSTRACT Sepsis remains a leading cause of mortality worldwide due to its profound biological heterogeneity. While multi‐omics approaches offer promise for precision medicine, existing datasets often lack longitudinal granularity or comprehensive clinical integration. We present the Chinese Multi‐omics Advances In Sepsis (CMAISE) cohort, a prospective,
Jie Yang +36 more
wiley +1 more source
Dysregulated Lipid Metabolism in Hepatocellular Carcinoma: Mechanisms and Therapeutic Strategies
Dysregulated lipid metabolism facilitates hepatocellular carcinoma (HCC) development, progression, immunosuppressive tumor microenvironment (TME) formation, and therapeutic resistance. Notably, the patterns of lipid metabolism vary significantly among different types of HCC driven by various etiologies.
Yi Yi +4 more
wiley +1 more source
A Case Report of a Special Type of Multiple Myeloma: Kappa Light Chain‐Only
This case illustrates the clinical course of a patient diagnosed with kappa light chain‐only multiple myeloma, a rare subtype of multiple myeloma. Of note, light chain multiple myeloma is characterized by rapid disease progression and severe target organ damage.
Yanhua Dai +8 more
wiley +1 more source
Amaç: Dünya çapında yaklaşık olarak 350 milyon kişinin hepatitis B virüsü (HBV) ile infekte olduğu düşünülmektedir. Noninfeksiyöz subviral bir partikül olan hepatit B yüzey antijeni (HBsAg) düzeyinin kantitatif analizi HBV infeksiyonlu bireylerde önemli ...
Kılıç, Süleyman
core
From HBV to MASLD Cirrhosis: Mechanistic Insights and Therapeutic Strategies
This review examines the epidemiological shift from hepatitis B virus (HBV) to metabolic dysfunction‐associated steatotic liver disease (MASLD) as the leading cause of cirrhosis globally. It highlights the distinct pathogenic mechanisms between HBV and MASLD cirrhosis and discusses evolving diagnostic tools and therapeutic strategies tailored to the ...
Hanqi Yu +5 more
wiley +1 more source
The Safety of Interferon‐Based Therapies in Chronic Hepatitis B Patients With Compensatory Cirrhosis
While nucleos(t)ide analog (Nuc) therapy is the standard for chronic hepatitis B, pegylated interferon‐alpha (Peg‐IFN‐α) provides unique advantages, including finite treatment duration and long‐term benefits. However, its use in patients with compensated cirrhosis remains limited due to persistent safety concerns about potential decompensation and ...
Qiran Zhang +32 more
wiley +1 more source

