Rapid quantification of semen hepatitis B virus DNA by real-time polymerase chain reaction [PDF]
, 2005 Aim: To examine the sensitivity and accuracy of real-time polymerase chain reaction (PCR) for the quantification of hepatitis B virus (HBV) DNA in semen.
Chen, Y +9 more
core +1 more source
Viruses, 2023 Background: The prevalence of HBV infection and HBV genotypes varies from country to country, and the role of HBV genotypes in the presence of HBV in the placenta and fetus has never been explored.
Sirinart Sirilert +5 more
doaj +1 more source
Association of mutations in the basal core promoter and pre-core regions of the hepatitis B viral genome and longitudinal changes in HBV level in HBEAG negative individuals: Results from a cohort study in northern Iran [PDF]
, 2015 Background: Although certain HBV mutations are known to affect the expression of Hepatitis e antigen, their association with HBV viral level or clinical outcomes is less clear.
Besharat, S. +7 more
core +1 more source
Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis [PDF]
, 2012 To examine the role of hepatitis B virus (HBV) integration in hepatocarcinogenesis, a systematic comparative study of both tumor and their corresponding non-tumor derived tissue has been conducted in a cohort of 60 HBV associated hepatocellular carcinoma
Chun-Ming Wong +13 more
core +8 more sources
Potential mutations associated with occult hepatitis B virus status [PDF]
, 2014 Context: Occult hepatitis B virus (HBV) status (OHBS) is simply defined as the presence of HBV DNA in the liver (with or without detectable HBV DNA in the serum), in the absence of serum HBV surface antigen (HBsAg). Importance of OHBS is mostly clinical,
Besharat, S. +2 more
core +1 more source
Intrahepatic HBV DNA as a predictor of antivirus treatment efficacy in HBeAg-positive chronic hepatitis B patients [PDF]
, 2007 AIM: To evaluate the effect of antiviral agents on intrahepatic HBV DNA in HBeAg-positive chronic hepatitis B patients. METHODS: Seventy-one patients received treatment with lamivudine, interferon alpha (IFN-alpha 2b) or sequential therapy with ...
Chen, Xin-Yue +10 more
core +1 more source
Nucleic Acid Testing for the Detection of HBV DNA [PDF]
Hepatitis Monthly, 2011 Dear Editor, We read with interest the article by Arababadi et al. [1], which highlights different and important areas of concern in the management of occult hepatitis B (OBI). There are two relevant issues worthy of discussion. First, the authors described the variable prevalence of OBI in different geographical regions worldwide.
Yuen, MF, Lai, CL, Seto, WK
openaire +4 more sources
Maternal HBeAg positivity and viremia associated with umbilical cord blood hepatitis B viremia
Pediatrics and Neonatology, 2019 Background: Hepatitis B (HBV) transmission may result from in utero transmission. We aimed to determine the correlation between maternal serum and umbilical cord blood HBV DNA levels in infants delivered by chronic HBV-infected mothers and to describe ...
Le Ye Lee +4 more
doaj +1 more source
HBV-Integration Studies in the Clinic: Role in the Natural History of Infection
Viruses, 2021 Hepatitis B virus (HBV) infection is a major global health problem causing acute and chronic liver disease that can lead to liver cirrhosis and hepatocellular carcinoma (HCC). HBV covalently closed circular DNA (cccDNA) is essential for viral replication
Teresa Pollicino, Giuseppe Caminiti
doaj +1 more source
HDV can constrain HBV genetic evolution in hbsag: Implications for the identification of innovative pharmacological targets [PDF]
, 2018 Chronic HBV + HDV infection is associated with greater risk of liver fibrosis, earlier hepatic decompensation, and liver cirrhosis hepatocellular carcinoma compared to HBV mono-infection.
Andreoni, Massimo +34 more
core +2 more sources