Results 21 to 30 of about 1,553,868 (271)
Proteogenomic characterization of cholangiocarcinoma
Hepatology, EarlyView., 2022 Proteogenomic characterization of cholangiocarcinoma with therapeutic strategies Abstract Background and Aims
Cholangiocarcinoma (CCA) is a highly heterogeneous cancer with limited understanding and few effective therapeutic approaches. We aimed at providing a proteogenomic CCA characterization to inform biological processes and treatment ...Mengjie Deng, Peng Ran, Lingli Chen, Yunzhi Wang, Zixiang Yu, Ke Cai, Jinwen Feng, Zhaoyu Qin, Yanan Yin, Subei Tan, Yang Liu, Chen Xu, Guoming Shi, Yuan Ji, Jian‐Yuan Zhao, Jian Zhou, Jia Fan, Yingyong Hou, Chen Ding +18 morewiley +1 more sourceMitochondrial stress in advanced fibrosis and cirrhosis associated with chronic hepatitis B, chronic hepatitis C, or nonalcoholic steatohepatitis
Hepatology, EarlyView., 2022 Adaptive mitochondrial mechanisms allow mitochondrial resilience and prevent the worsening of fibrosis, while deregulation of these mechanisms promotes the progression from no/minimal‐mild (F0‐F2) fibrosis to advanced fibrosis and cirrhosis (F3‐F4). Abstract Background and Aims
Hepatitis B virus (HBV) infection causes oxidative stress (OS) and alters ...Dimitri Loureiro, Issam Tout, Stéphanie Narguet, Cheikh Mohamed Bed, Morgane Roinard, Ahmad Sleiman, Nathalie Boyer, Nathalie Pons‐Kerjean, Corinne Castelnau, Nathalie Giuly, Dorothy Tonui, Vassili Soumelis, Jamel El Benna, Patrick Soussan, Richard Moreau, Valérie Paradis, Abdellah Mansouri, Tarik Asselah +17 morewiley +1 more source3D landscape of Hepatitis B virus interactions with human chromatins
Cell Discovery, 2020 Hepatitis B viral (HBV) DNAs, including covalently closed circular DNA (cccDNA) and integrated HBV DNA forms, are considered to be primary contributors to the development and progression of HBV-associated liver diseases.Bo Yang, Boyuan Li, Liyang Jia, Yongpeng Jiang, Xin Wang, Shaodong Jiang, Shunda Du, Xiong Ji, Pengyuan Yang +8 moredoaj +1 more sourceHealth disparities in chronic liver disease
Hepatology, EarlyView., 2022 Abstract
The syndemic of hazardous alcohol consumption, opioid use, and obesity has led to important changes in liver disease epidemiology that have exacerbated health disparities. Health disparities occur when plausibly avoidable health differences are experienced by socially disadvantaged populations.Ani Kardashian, Marina Serper, Norah Terrault, Lauren D. Nephew +3 morewiley +1 more sourceChanges in viral load and HBsAg and HBeAg status with age in HBV chronic carriers in The Gambia. [PDF]
, 2008 BACKGROUND: Little is known about changes in hepatitis B viral load (HBV DNA) in relation to age in Africa. The aim of this study is to determine the natural course of HBV chronic infection, particularly in relation to sequential changes in serum HBV DNA Jeffries, David, Kaye, Steve, Hilton C. Whittle (7946705), David Jeffries, Maimuna E Mendy, Samuel J McConkey, Steve Kaye, Samuel McConkey (7896113), Marianne AB Sande van der (7946780), Kaye Steve, Mendy, Maimuna E, Maimuna E. Mendy (7946657), Hall, Andrew J, Mendy Maimuna E, Andrew J Hall, Crozier, Sarah, McConkey, Samuel J, Sarah Crozier (46005), Sande van der, Marianne AB, Steve Kaye (46006), Whittle, Hilton C, Andrew J. Hall (78002), Whittle Hilton C, Sande van der Marianne AB, Hilton C Whittle, Marianne AB Sande van der, David Jeffries (46007), Sarah Crozier, Jeffries David, McConkey Samuel J, Hall Andrew J, Crozier Sarah +31 morecore +1 more sourceTP53 R249S mutation in hepatic organoids captures the predisposing cancer risk
Hepatology, EarlyView., 2022 The systematic approach in elucidating the gain‐of‐function (GOF) roles of TP53 mutations in early liver carcinogenesis. Unique downstream targets of TP53 L3 mutations were identified from chormatin immunoprecipitation sequencing in HCC cell lines, followed by a series of validation assays to substantiate the exclusive transcriptional regulations ...Yin Kau Lam, Jianqing Yu, Hao Huang, Xiaofan Ding, Alissa M. Wong, Howard H. Leung, Anthony W. Chan, Kelvin K. Ng, Mingjing Xu, Xin Wang, Nathalie Wong +10 morewiley +1 more sourceSuppression of HBV by Tenofovir in HBV/HIV coinfected patients : a systematic review and meta-analysis [PDF]
, 2013 Background: Hepatitis B coinfection is common in HIV-positive individuals and as antiretroviral therapy has made death due to AIDS less common, hepatitis has become increasingly important. Several drugs are available to treat hepatitis B. The most potent Thomas Reiberger, Richard Gilson, Noriyoshi Kuzushita, Firouze Bani-Sadr (432319), Nüesch, R, David Dunn (37023), Marina Núñez, Lionel Tan, Stephan Christoph, Peters, M, Tan, L (Lionel), Pillay, Deenan, Huw Price, de Vries-Sluijs, T, Reto Nüesch, Dunn, David, Peters, Marion, Kuzushita, N, Kuzushita Noriyoshi, Firouze Bani-Sadr, Bani-Sadr, Firouze, Mauss Stefan, Reiberger, Thomas, Stefan Mauss, Gilson, Richard, Mauß, Stefan, Mamta K Jain, Theodora de Vries-Sluijs, Tan, Lionel, Gilson, R, Price, H, Gilson Richard, Huw Price (300124), Jain Mamta K., Peters Marion, Reiberger Thomas, Thomas Reiberger (143056), Nüesch Reto, Price, Huw, Richard Gilson (125405), David Dunn, Reto Nüesch (432324), Nüesch, Reto, Marina Núñez (432323), Pillay Deenan, Deenan Pillay (7888), Price Huw, Tan, L, Tan Lionel, Dunn David, Kuzushita, Noriyoshi, Christoph Stephan (283267), Stephan, C, Christoph Stephan, Pillay, D, Núñez Marina, Núñez, M, Stefan Mauss (143062), Bani-Sadr, F, Peters, M (Marjolein), Jain, MK, Bani-Sadr Firouze, de Vries-Sluijs Theodora, Stephan, Christoph, Theodora de Vries-Sluijs (432320), Lionel Tan (124548), Dunn, D, Marion Peters, Reiberger, T, Mamta K. Jain, Noriyoshi Kuzushita (432322), Mamta K. Jain (432321), Marion Peters (403490), Mauss, S, Jain, Mamta K., Núñez, Marina, Deenan Pillay, Nueesch, R, Vries-Sluijs, Theodora de, Peters, M.G. (Marion), Núñez, M.J. (Marina), Pillay, D. (Deenan), Nüesch, E. (Eveline), Tan, L. (Lionel), Price, H. (Huw), Mauss, S. (Stefan), Gilson, E. (Eric), Dunn, D. (David), Jain, A. (Ashok), Vriessluijs, T.E.M.S. (Theodora) de, Bani-Sadr, F. (Firouze), Stephan, C. (Carsten), Kuzushita, N. (Noriyoshi), Reiberger, T. (Thomas) +93 morecore +2 more sourcesRe-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis [PDF]
, 2012 To examine the role of hepatitis B virus (HBV) integration in hepatocarcinogenesis, a systematic comparative study of both tumor and their corresponding non-tumor derived tissue has been conducted in a cohort of 60 HBV associated hepatocellular carcinoma Hui Zhuang (139189), Chen, Xiangmei, Malcolm A McCrae, Pei-Jer Chen, Weijie Li (139178), Pei-Jer Chen (53402), Jiangbo Zhang, Lu, Fengmin, Xu, Chunhui, Suzhen Jiang, Chen Xiangmei, Yang, Ziwei, McCrae Malcolm A., Ziwei Yang (139177), Jinlin Hou, Jiang, Suzhen, Malcolm A. McCrae (139183), Ziwei Yang, Chen, Pei-Jer, Weijie Li, Zhang Jiangbo, Hou Jinlin, Xiaojun Li (138162), Zhuang, Hui, Yang Ziwei, Suzhen Jiang (139176), Li Xiaojun, Hui Zhuang, Lu Fengmin, Wang, Yongfeng, Jinlin Hou (59138), Hou, Jinlin, Xiangmei Chen (139185), Xu Chunhui, Chunhui Xu (139181), Fengmin Lu (139191), Yongfeng Wang, Xiaojun Li, Wang Yongfeng, Li Weijie, Zhang, Jiangbo, Chunhui Xu, Li, Weijie, McCrae, Malcolm A., Xiangmei Chen, Jiangbo Zhang (139180), Jiang Suzhen, Li, Xiaojun, Zhuang Hui, Yongfeng Wang (139179), Chen Pei-Jer, Fengmin Lu +51 morecore +1 more source52-week efficacy and safety of telbivudine with conditional tenofovir intensification at week 24 in HBeAg-positive chronic Hepatitis B [PDF]
, 2013 Background and Aims: The Roadmap concept is a therapeutic framework in chronic hepatitis B for the intensification of nucleoside analogue monotherapy based on early virologic response.Tawesak Tanwandee (279135), Jorge Daruich, Wattana Sukeepaisarnjaroen, Rashidkhan Pathan, Eduardo Fassio, Fernando Bessone (254729), Suzane K Ono, Daruich, Jorge, Pessôa, Mário Guimarães, Yuhong Dong, Tanwandee, Tawesak, Rashidkhan Pathan (279143), Sukeepaisarnjaroen, Wattana, Mário G Pessôa, Ono, Suzane K., Teerha Piratvisuth (279131), Piyawat Komolmit (279133), Chan, Henry L. Y., Henry L Y Chan, Dong, Yuhong, Piratvisuth, Teerha, Pessôa, Mário G., Mário G. Pessôa (279138), Stefan Zeuzem (22856), Hugo Cheinquer (279142), Stefan Zeuzem, Trylesinski, Aldo, Pathan, Rashidkhan, Bessone, Fernando, Suzane K. Ono (279140), Henry L. Y. Chan (279137), Aldo Trylesinski (279145), Fassio, Eduardo, Piyawat Komolmit, Henry L. Y. Chan, Ono, Suzane Kioko, Komolmit, Piyawat, Jorge Daruich (279141), Hugo Cheinquer, Eduardo Fassio (279139), Cheinquer, Hugo, Chan, Henry, Tawesak Tanwandee, Mário G. Pessôa, Aldo Trylesinski, Suzane K. Ono, Teerha Piratvisuth, Fernando Bessone, Wattana Sukeepaisarnjaroen (279136), Yuhong Dong (279144), Zeuzem, Stefan +50 morecore +2 more sources
