Results 121 to 130 of about 9,710 (220)
Establishment of gene-transfected cell strain L02/HBx and effect of HBx on the cell cycles
World Chinese Journal of Digestology, 2007 Bin Cheng +3 more
openaire +1 more source
HBx suppresses insulin-inhibitory expression of gluconeogenic genes.
, 2013 (A) The promoter activity of PEPCK and G6Pase by HBx and SOCS3. HepG2 cells were transfected with two promoters of PEPCK (left) and G6Pase (right) and expression vectors of HBx, and SOCS3. (B) The inhibition of insulin-mediated promoter activity of PEPCK
JaeHun Cheong (366273) +2 more
core +1 more source
Role of P2X7 receptor in HBx-mediated hepatitis
, 2015 학위논문 (석사)-- 서울대학교 대학원 : 약학과(약물학), 2015. 8. 강건욱.B형 간염을 일으키는 B형 간염 바이러스(Hepatitis B virus)는 여러 경로를 통해 급성 및 만성 간염을 일으키며 그 중 일부 환자군에서 간경변 및 간암으로 진행되는 것이 알려져 있다.
고기훈
core
Base excision repair is inhibited by HBx.
, 2013 The effect of HBx and TDG on BER activity is given as the ratio between the luciferase activity of pG/T (mismatch) and pG/C (positive control) vectors after subtraction of the activity of the pA/T (negative control) vector.
Hans L. Zaaijer (142547) +3 more
core +1 more source
Zhongshan Daxue xuebao. Yixue kexue ban, 2000 【目的】研究转 HBx 基因肝癌细胞增殖与拮抗凋亡特性,探讨肝癌恶性表型的分子基础。【方法】以携 HBx 基因 重组逆转录病毒感染 QGY7701肝癌细胞, G418 筛选,PCR 与 RT-PCR 鉴定; 流式细胞仪( FCM)检测细胞增殖周期; 用阿霉素 诱导细胞凋亡,FCM 定量检测。【结果】QGY7701 肝癌细胞经 HBx 基因转染后,G418 筛选 4～ 6 周获阳性克隆株 QGY/HBx, PCR 与 RT -PCR 分别证实细胞有 HBx 基因整合与 HBx mRNA 表达 ...
闵 军, 刘彦文, 余新炳
doaj
HBx targets centrosomal protein TAX1BP2 to promote genomic instability
, 2015 Centrosome is a major microtubule-organizing centre for regulating spindle assembly and bipolarity.Evidence suggests that cancer is a multi-step accumulation process of genomic instability resulted from centrosome dysfunction.
Tang, HC +4 more
core
Journal of Current Oncology and Medical SciencesDeath from liver cancer spreads wide, mainly fueled by persistent hepatitis B or C infections. Not alike in origin, yet both viruses twist liver cell routines - genetically, operationally - to spark malignancy.
Aida Abbasi, Arefeh Zabeti Touchaei
doaj
Solubilization and purification studies of GST-HBx-6His
, 2010 The Hepatitis B Virus X (HBx) protein is a protein expressed within an organism’s body infected with the Hepatitis B Virus (HBV). Its characterization in depth could develop an improved treatment for both acute and chronic Hepatitis B patients.
Goh, Kester Zhi Hao.
core
[The E3 ubiquitin ligase KLHL8 degrades HBx protein via the ubiquitin-proteasome pathway and inhibits HBV cccDNA transcription]. [PDF]
Zhonghua Gan Zang Bing Za ZhiLiu ZH +6 more
europepmc +1 more source